Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Daoqi You"'
Autor:
Heathcliff Dorado García, Fabian Pusch, Yi Bei, Jennifer von Stebut, Glorymar Ibáñez, Kristina Guillan, Koshi Imami, Dennis Gürgen, Jana Rolff, Konstantin Helmsauer, Stephanie Meyer-Liesener, Natalie Timme, Victor Bardinet, Rocío Chamorro González, Ian C. MacArthur, Celine Y. Chen, Joachim Schulz, Antje M. Wengner, Christian Furth, Birgit Lala, Angelika Eggert, Georg Seifert, Patrick Hundsoerfer, Marieluise Kirchner, Philipp Mertins, Matthias Selbach, Andrej Lissat, Frank Dubois, David Horst, Johannes H. Schulte, Simone Spuler, Daoqi You, Filemon Dela Cruz, Andrew L. Kung, Kerstin Haase, Michela DiVirgilio, Monika Scheer, Michael V. Ortiz, Anton G. Henssen
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Alveolar rhabdomyosarcoma is a clinically challenging disease due to the lack of druggable targets. Here the authors show preclinical evidence for ATR inhibitors as a therapeutic option for alveolar rhabdomyosarcoma.
Externí odkaz:
https://doaj.org/article/7544d8ec795c4dae8babbe7a0a303edd
Autor:
Prabhjot S. Mundi, Filemon S. Dela Cruz, Adina Grunn, Daniel Diolaiti, Audrey Mauguen, Allison R. Rainey, Kristina Guillan, Armaan Siddiquee, Daoqi You, Ronald Realubit, Charles Karan, Michael V. Ortiz, Eugene F. Douglass, Melissa Accordino, Suzanne Mistretta, Frances Brogan, Jeffrey N. Bruce, Cristina I. Caescu, Richard D. Carvajal, Katherine D. Crew, Guarionex Decastro, Mark Heaney, Brian S. Henick, Dawn L. Hershman, June Y. Hou, Fabio M. Iwamoto, Joseph G. Jurcic, Ravi P. Kiran, Michael D. Kluger, Teri Kreisl, Nicole Lamanna, Andrew B. Lassman, Emerson A. Lim, Gulam A. Manji, Guy M. McKhann, James M. McKiernan, Alfred I. Neugut, Kenneth P. Olive, Todd Rosenblat, Gary K. Schwartz, Catherine A. Shu, Michael B. Sisti, Ana Tergas, Reena M. Vattakalam, Mary Welch, Sven Wenske, Jason D. Wright, Peter Canoll, Hanina Hibshoosh, Kevin Kalinsky, Mahalaxmi Aburi, Peter A. Sims, Mariano J. Alvarez, Andrew L. Kung, Andrea Califano
Publikováno v:
Cancer Discovery. :OF1-OF22
Predicting in vivo response to antineoplastics remains an elusive challenge. We performed a first-of-kind evaluation of two transcriptome-based precision cancer medicine methodologies to predict tumor sensitivity to a comprehensive repertoire of clin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2372be69c8c6242e5877bc9ce0d6bdc4
https://doi.org/10.1158/2159-8290.cd-22-1020
https://doi.org/10.1158/2159-8290.cd-22-1020
Supplementary Figure 1 from Comprehensive Molecular Profiling of Desmoplastic Small Round Cell Tumor
Autor:
Neerav Shukla, Marc Ladanyi, Ahmet Zehir, Elli Papaemmanuil, Andrew L. Kung, Paul A. Meyers, Leonard H. Wexler, Michael P. LaQuaglia, Todd E. Heaton, Justin T. Gerstle, Gunes Gundem, Daoqi You, Nancy Bouvier, Katherine A. Thornton, Mrinal M. Gounder, William D. Tap, Shakeel Modak, Nestor Rosales, Glorymar I. Sanchez, Diego F. Coutinho, Filemon Dela Cruz, Max F. Levine, Anita S. Bowman, Emily K. Slotkin
Supplementary Figure 1 depicts copy number alterations in the described cohort
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8092c0a779e8af5f72ce9dfe30cdf632
https://doi.org/10.1158/1541-7786.22525995.v1
https://doi.org/10.1158/1541-7786.22525995.v1
Autor:
Stephen S. Roberts, David M. Hyman, Andrew L. Kung, Elli Papaemmanuil, Marc Ladanyi, Andrea Califano, Robert Darnell, Lee Spraggon, Hongxu Ding, Irena Gushterova, Audrey Mauguen, Lillian M. Smyth, Achim A. Jungbluth, Ryma Benayed, Glorymar Ibanez Sanchez, Sagarika Pachhal, Peilin Ma, Daoqi You, Max F. Levine, Venkata D. Yellapantula, Gunes Gundem, Jennifer J. Clark, Filemon S. Dela Cruz, Neerav N. Shukla, Daniel Diolaiti, Emily K. Slotkin
Supplementary Table 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d95d232cde81ddfe4e3b8eeff74692ca
https://doi.org/10.1158/2159-8290.22532650.v1
https://doi.org/10.1158/2159-8290.22532650.v1
Autor:
Andrew M. Intlekofer, Eytan M. Stein, Ghassan K. Abou-Alfa, Ross L. Levine, Luis A. Diaz, Ingo K. Mellinghoff, Yelena Y. Janjigian, Bin Wu, Sung Choe, Bin Fan, Guowen Liu, Kyle J. MacBeth, Mark G. Frattini, Alessandra Tosolini, Elli Papaemmanuil, Lydia W.S. Finley, Ed Reznik, David M. Hyman, Martin S. Tallman, Agnes Viale, S. Duygu Selcuklu, Daoqi You, Ahmet Zehir, Richard K. Do, Mikhail Roshal, Minal Patel, Christopher Famulare, Shengqi Hou, Juan M. Schvartzman, Alan H. Shih, Maeve A. Lowery, James J. Harding
Next-generation sequencing and droplet digital PCR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e6b1f6e925859e5fdfef81d0c5d8e54
https://doi.org/10.1158/2159-8290.22533422
https://doi.org/10.1158/2159-8290.22533422
Autor:
Stephen S. Roberts, David M. Hyman, Andrew L. Kung, Elli Papaemmanuil, Marc Ladanyi, Andrea Califano, Robert Darnell, Lee Spraggon, Hongxu Ding, Irena Gushterova, Audrey Mauguen, Lillian M. Smyth, Achim A. Jungbluth, Ryma Benayed, Glorymar Ibanez Sanchez, Sagarika Pachhal, Peilin Ma, Daoqi You, Max F. Levine, Venkata D. Yellapantula, Gunes Gundem, Jennifer J. Clark, Filemon S. Dela Cruz, Neerav N. Shukla, Daniel Diolaiti, Emily K. Slotkin
Supplementary Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1eb9a2340f776281a6eeb3087724be20
https://doi.org/10.1158/2159-8290.22532656.v1
https://doi.org/10.1158/2159-8290.22532656.v1
Autor:
Stephen S. Roberts, David M. Hyman, Andrew L. Kung, Elli Papaemmanuil, Marc Ladanyi, Andrea Califano, Robert Darnell, Lee Spraggon, Hongxu Ding, Irena Gushterova, Audrey Mauguen, Lillian M. Smyth, Achim A. Jungbluth, Ryma Benayed, Glorymar Ibanez Sanchez, Sagarika Pachhal, Peilin Ma, Daoqi You, Max F. Levine, Venkata D. Yellapantula, Gunes Gundem, Jennifer J. Clark, Filemon S. Dela Cruz, Neerav N. Shukla, Daniel Diolaiti, Emily K. Slotkin
Supplementary Table 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c512d48d59d9f8c1814d997c82303fa
https://doi.org/10.1158/2159-8290.22532647.v1
https://doi.org/10.1158/2159-8290.22532647.v1
Autor:
Stephen S. Roberts, David M. Hyman, Andrew L. Kung, Elli Papaemmanuil, Marc Ladanyi, Andrea Califano, Robert Darnell, Lee Spraggon, Hongxu Ding, Irena Gushterova, Audrey Mauguen, Lillian M. Smyth, Achim A. Jungbluth, Ryma Benayed, Glorymar Ibanez Sanchez, Sagarika Pachhal, Peilin Ma, Daoqi You, Max F. Levine, Venkata D. Yellapantula, Gunes Gundem, Jennifer J. Clark, Filemon S. Dela Cruz, Neerav N. Shukla, Daniel Diolaiti, Emily K. Slotkin
Supplementary Figures and Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::458fe65f33ce15c1f438256aea2575e3
https://doi.org/10.1158/2159-8290.22532659
https://doi.org/10.1158/2159-8290.22532659
Autor:
Neerav Shukla, Marc Ladanyi, Ahmet Zehir, Elli Papaemmanuil, Andrew L. Kung, Paul A. Meyers, Leonard H. Wexler, Michael P. LaQuaglia, Todd E. Heaton, Justin T. Gerstle, Gunes Gundem, Daoqi You, Nancy Bouvier, Katherine A. Thornton, Mrinal M. Gounder, William D. Tap, Shakeel Modak, Nestor Rosales, Glorymar I. Sanchez, Diego F. Coutinho, Filemon Dela Cruz, Max F. Levine, Anita S. Bowman, Emily K. Slotkin
Supplementary Table 1 shows point mutations found in DSRCT samples
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18101e727b13883957a6aa77461d9c6b
https://doi.org/10.1158/1541-7786.22525983
https://doi.org/10.1158/1541-7786.22525983
Supplementary Figure 3 from Comprehensive Molecular Profiling of Desmoplastic Small Round Cell Tumor
Autor:
Neerav Shukla, Marc Ladanyi, Ahmet Zehir, Elli Papaemmanuil, Andrew L. Kung, Paul A. Meyers, Leonard H. Wexler, Michael P. LaQuaglia, Todd E. Heaton, Justin T. Gerstle, Gunes Gundem, Daoqi You, Nancy Bouvier, Katherine A. Thornton, Mrinal M. Gounder, William D. Tap, Shakeel Modak, Nestor Rosales, Glorymar I. Sanchez, Diego F. Coutinho, Filemon Dela Cruz, Max F. Levine, Anita S. Bowman, Emily K. Slotkin
Supplementary Figure 3 provides a breakdown of the structural variant types found via whole genome sequencing in DSRCT samples
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::418c34cb259455575b8d45bb37c7fa9d
https://doi.org/10.1158/1541-7786.22525989
https://doi.org/10.1158/1541-7786.22525989