Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Daojun Diao"'
Autor:
Kai Zhang, Dingdong Liu, Yafei Li, Zhencan Shi, Jun Guo, Chengjiang Gao, Hu Wang, Zhenyu Ju, Daojun Diao
Publikováno v:
Haematologica, Vol 108, Iss 8 (2023)
Hematopoietic stem cells (HSC) are kept in a quiescent state to maintain their self-renewal capacity. Proper regulation of cyclin-dependent kinases (CDK) and cyclin proteins is critical for the maintenance of HSC homeostasis. Here, we found that the
Externí odkaz:
https://doaj.org/article/a963ad8c505a4ea6a744ed4b058ac6b7
Autor:
Kai Zhang, Dingdong Liu, Yafei Li, Zhencan Shi, Jun Guo, Chengjiang Gao, Hu Wang, Zhenyu Ju, Daojun Diao
Publikováno v:
Haematologica.
Hematopoietic stem cells (HSCs) are kept in a quiescent state to maintain their self-renewal capacity. Proper regulation of cyclin-dependent kinases (CDKs) and cyclin proteins is critical for the maintenance of HSC homeostasis. Here, we found the E3
Autor:
Dingdong Liu, Li Yu, Zhencan Shi, Yugang Qiu, Yafei Li, Kai Zhang, Zhangfa Song, Zhenyu Ju, Ying Luo, Daojun Diao, Yanan Zhao
Publikováno v:
Aging Cell
Hematopoietic stem cells (HSCs) reside in a quiescent niche to reserve their capacity of self‐renewal. Upon hematopoietic injuries, HSCs enter the cell cycle and encounter protein homeostasis problems caused by accumulation of misfolded proteins. H
Autor:
Joseph Loscalzo, Hu Wang, Zeping Hu, Daojun Diao, Xudong Zhu, Yuzheng Zhao, Bo Liu, Tangliang Li, Lijuan Song, Weiyan Shen, Johan Auwerx, Chengtao Li, Hongbo Zhang, Genxiang Mao, Zhenyu Ju, Yugang Qiu, Yejun Zou, Wengong Wang, Ke Yao, Ping Huang, Yi Yang, Yong Zhou
Publikováno v:
Circ Res
Rationale: PGC1α (peroxisome proliferator-activated receptor gamma coactivator 1α) represents an attractive target interfering bioenergetics and mitochondrial homeostasis, yet multiple attempts have failed to upregulate PGC1α expression as a thera
Autor:
Ye Feng, Li Chen, Daojun Diao, Weiyan Shen, Zhenyu Ju, Lingling Zhang, Tangliang Li, Xudong Zhu, Chaohui Yu, Peihao Liu, Leiming Liu, Hu Wang, Fan Yang, Weihua Zhou, Xingyong Wan, Jian Ren, Qi Zhao, Jing Li, Sheng Yan
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental BiologyREFERENCES. 34(8)
Inflammatory responses are pivotal incidences in hepatic metabolic derangements. However, the underlying mechanism remains elusive. The present study aimed to evaluate the role of peroxisome proliferator-activated receptor-gamma, coactivator 1 alpha
Autor:
Xudong Zhu, You Wu, K. Lenhard Rudolph, Zhencan Shi, Shaorong Gao, Guang-Hui Liu, Tangliang Li, Daojun Diao, Yawei Gao, Xiaoyu Liu, Hu Wang, Zhenyu Ju
Publikováno v:
Cell Stem Cell. 18:495-507
Proper regulation of Wnt signaling is critical for the maintenance of hematopoietic stem cell (HSC) homeostasis. The epigenetic regulation of Wnt signaling in HSCs remains largely unknown. Here, we report that the histone deacetylase SIRT6 regulates
Autor:
Zhangfa Song, Zhencan Shi, Xudong Zhu, Daojun Diao, Xiaoqing Jin, Fan Yang, Jing Yan, Yu-Sheng Cong, Tangliang Li, Hu Wang, Tobias Sperka, Zhenyu Ju, Meimei Zhang, Li Shen, Qimin Zhan
Publikováno v:
EMBO reports. 19
Progressive attrition of telomeres triggers DNA damage response (DDR) and limits the regenerative capacity of adult stem cells during mammalian aging. Intriguingly, telomere integrity is not only determined by telomere length but also by the epigenet
Publikováno v:
Journal of Biological Chemistry
The structure and mode of binding of the endoplasmic reticulum protein disulfide isomerase-related proteins to their substrates is currently a focus of intensive research. We have recently determined the crystal structure of the Drosophila melanogast