Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Daojiang Yan"'
Autor:
Qian Wei, Jian Bai, Daojiang Yan, Xiuqi Bao, Wenting Li, Bingyu Liu, Dan Zhang, Xiangbing Qi, Dequan Yu, Youcai Hu
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 2, Pp 572-587 (2021)
Endophytic fungi are promising producers of bioactive small molecules. Bioinformatic analysis of the genome of an endophytic fungus Penicillium dangeardii revealed 43 biosynthetic gene clusters, exhibited its strong ability to produce numbers of seco
Externí odkaz:
https://doaj.org/article/2c3a43fcb7034fea8a92f6c76f8037bd
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 8, Iss 4, Pp 687-697 (2018)
Epigenetic modifications have been proved to be a powerful way to activate silent gene clusters and lead to diverse secondary metabolites in fungi. Previously, inactivation of a histone H3 deacetylase in Calcarisporium arbuscula had led to pleiotropi
Externí odkaz:
https://doaj.org/article/ce0e2c4d0234496bb38a0a48c1d3cde7
Autor:
Yilan Liu, Maohua Yang, Jinjin Chen, Daojiang Yan, Wanwan Cheng, Yanyan Wang, Anders Thygesen, Ruonan Chen, Jianmin Xing, Qinhong Wang, Yanhe Ma
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0149762 (2016)
Efficiency and fidelity are the key obstacles for genome editing toolboxes. In the present study, a PCR-based tandem repeat assisted genome editing (TRAGE) method with high efficiency and fidelity was developed. The design of TRAGE is based on the me
Externí odkaz:
https://doaj.org/article/f65a816b10834f739f7cd77216f3ea60
Publikováno v:
Journal of the American Chemical Society. 144:4269-4276
Autor:
Xiangbing Qi, Daojiang Yan, Jian Bai, Qian Wei, Wenting Li, Dan Zhang, Bingyu Liu, Youcai Hu, De-Quan Yu, Xiuqi Bao
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 2, Pp 572-587 (2021)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Endophytic fungi are promising producers of bioactive small molecules. Bioinformatic analysis of the genome of an endophytic fungus Penicillium dangeardii revealed 43 biosynthetic gene clusters, exhibited its strong ability to produce numbers of seco
Autor:
Youcai Hu, Yalong Zhang, Yan-hua Mou, Jiawang Liu, Daojiang Yan, Jian Bai, Chen Zhang, Bingyu Liu
Publikováno v:
Chinese Herbal Medicines. 13:98-104
Objective Peptidyl alkaloids, a series of important natural products can be assembled by fungal non-ribosomal peptide synthetases (NRPSs). However, many of the NRPSs associated gene clusters are silent under laboratory conditions, and the traditional
Autor:
Youcai Hu, Ya-Nan Wang, Jian Bai, Li-Hua Zhang, Le Zhang, Daojiang Yan, Chen Zhang, Bingyu Liu
Publikováno v:
Organic Chemistry Frontiers. 8:5926-5933
Three phomoidride-type dimeric anhydrides, phomoidrides E–G (1–3), were isolated from the fungus Pleosporales sp. Their structures were elucidated by comprehensive spectroscopic analyses. Phomoidride E (1) possesses a totally new caged tricyclo[5
Autor:
Youcai Hu, Yan-hua Mou, Yalong Zhang, Daojiang Yan, Bingyu Liu, Chen Zhang, Le Zhang, Minghua Chen, Jian Bai
Publikováno v:
Journal of Natural Products. 83:3262-3269
Seven new β-caryophyllene derivatives, pestalotiphains A-G (1-7), along with six known analogues (8-13), were isolated from the plant-associated Pestalotiopsis hainanensis. Compound 1 represents the first example of a caryophyllene-adenine hybrid, a
Publikováno v:
Chinese Journal of Natural Medicines. 17:394-400
Six novel monacolin analogs, monacolins V1-V6 (1-6), together with seven known ones (7-13), were isolated from the ethyl acetate extract of red yeast rice. Their structures and absolute configurations were determined by spectroscopic methods, especia
Autor:
Youcai Hu, Chen Qibin, Bingyu Liu, Yalong Zhang, Le Zhang, Jian Bai, Daojiang Yan, Chen Zhang, Jie Gao, Yi Zou
Publikováno v:
Organic Letters. 21:1475-1479
Fumiquinazolines are multicyclic peptidyl alkaloids where FAD-dependent oxidases are main tailing redox enzymes in their biosynthesis. Here, we characterized the use of an α-KG/Fe(II)-dependent dioxygenase (α-KGD) as a new strategy in Nature to inc