Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Daochun Luo"'
Autor:
Olivia Goltsis, Claudia Bilodeau, Jinxia Wang, Daochun Luo, Meisam Asgari, Laurent Bozec, Ante Pettersson, Sandra L. Leibel, Martin Post
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Background Chronic lung disease of prematurity, called bronchopulmonary dysplasia (BPD), lacks effective therapies, stressing the need for preclinical testing systems that reflect human pathology for identifying causal pathways and testing n
Externí odkaz:
https://doaj.org/article/45f4836b8b3d47b6a96bf312114b0597
Autor:
Claudia Bilodeau, Sharareh Shojaie, Olivia Goltsis, Jinxia Wang, Daochun Luo, Cameron Ackerley, Ian M Rogers, Brian Cox, Martin Post
Publikováno v:
npj Regenerative Medicine, Vol 6, Iss 1, Pp 1-12 (2021)
Abstract The use of decellularized whole-organ scaffolds for bioengineering of organs is a promising avenue to circumvent the shortage of donor organs for transplantation. However, recellularization of acellular scaffolds from multicellular organs li
Externí odkaz:
https://doaj.org/article/8588797879864052b1564c0cf5b704ba
Autor:
Evan Y. Snyder, Jinxia Wang, Alicia M. Winquist, Irene Tseu, Sharareh Shojaie, Daochun Luo, Neal H. Nathan, Martin Post, Sandra L Leibel
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-15 (2019)
Scientific Reports
Scientific Reports
Surfactant protein B (SFTPB) deficiency is a fatal disease affecting newborn infants. Surfactant is produced by alveolar type II cells which can be differentiated in vitro from patient specific induced pluripotent stem cell (iPSC)-derived lung organo
Autor:
Brian J. Cox, Sharareh Shojaie, Claudia Bilodeau, Daochun Luo, Martin Post, Ian M. Rogers, Cameron Ackerley, Jinxia Wang, Olivia Goltsis
Publikováno v:
npj Regenerative Medicine, Vol 6, Iss 1, Pp 1-12 (2021)
NPJ Regenerative Medicine
NPJ Regenerative Medicine
The use of decellularized whole-organ scaffolds for bioengineering of organs is a promising avenue to circumvent the shortage of donor organs for transplantation. However, recellularization of acellular scaffolds from multicellular organs like the lu
Autor:
Johan C. de Jongste, Minke van Tuyl, Jeroen Tibboel, Cameron Ackerley, Jinxia Wang, Freek Groenman, Daochun Luo, Irene Tseu, Dick Tibboel, Johanna Selvaratnam, Zhen Huang, Isabella Caniggia, Martin Post
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology, 52(4), 448-458. American Thoracic Society
Tibboel, J, Groenman, F A, Selvaratnam, J, Wang, J, Tseu, I, Huang, Z, Caniggia, I, Luo, D, Tuyl, M V, Ackerley, C, Jongste, J C D, Tibboel, D & Post, M 2015, ' Hypoxia-inducible factor-1 stimulates postnatal lung development but does not prevent o2-induced alveolar injury ', American Journal of Respiratory Cell and Molecular Biology, vol. 52, no. 4, pp. 448-458 . https://doi.org/10.1165/rcmb.2014-0037OC
American Journal of Respiratory Cell and Molecular Biology
Tibboel, J, Groenman, F A, Selvaratnam, J, Wang, J, Tseu, I, Huang, Z, Caniggia, I, Luo, D, Tuyl, M V, Ackerley, C, Jongste, J C D, Tibboel, D & Post, M 2015, ' Hypoxia-inducible factor-1 stimulates postnatal lung development but does not prevent o2-induced alveolar injury ', American Journal of Respiratory Cell and Molecular Biology, vol. 52, no. 4, pp. 448-458 . https://doi.org/10.1165/rcmb.2014-0037OC
American Journal of Respiratory Cell and Molecular Biology
This study investigated whether hypoxia-inducible factor (HIF)-1 influences postnatal vascularization and alveologenesis in mice and whether stable (constitutive-active) HIF could prevent hyperoxia-induced lung injury. We assessed postnatal vessel an
Publikováno v:
Molecular Cancer Research. 9:234-245
The transcriptional inhibitor Snail is a critical regulator for epithelial–mesenchymal transition (EMT). Although low oxygen induces Snail transcription, thereby stimulating EMT, a direct role of hypoxia-inducible factor (HIF) in this process remai
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 174:581-589
Fibroblast growth factor receptor-1alpha(IIIc) [FGF-R1alpha(IIIc)] regulates recovery of neonatal rat lung growth, after 95% oxygen-mediated growth arrest. Its role in normal postnatal alveologenesis is unknown.To determine if FGF-R1alpha(IIIc) regul
Publikováno v:
The Biochemical journal. 461(3)
BOK (BCL-2-related ovarian killer) is a member of the pro-apoptotic BCL-2 family that is highly expressed in the human placenta. BOK excess causes increased trophoblast autophagy and apoptosis in pre-eclampsia, a pathological condition of hypoxia and
Autor:
Paul Basset, Marie-Gabrielle Ludwig, Isabelle Stoll, Daochun Luo, Eric Guérin, Patrick Anglard
Publikováno v:
Journal of Biological Chemistry. 274:37177-37185
Stromelysin-3 (ST3) is a matrix metalloproteinase whose synthesis is markedly increased in stromal fibroblasts of most invasive human carcinomas. In the present study, we have investigated the molecular mechanisms by which high levels of ST3 expressi
Publikováno v:
American journal of physiology. Lung cellular and molecular physiology. 296(5)
Maternal bacterial infections adversely affect lung development by crossing the placental barrier and infecting the developing fetus. The underlying mechanism negatively affecting pulmonary development remains unknown. Herein, we investigated whether