Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Dao-Yu Zhang"'
Autor:
Xiao-Qing Yuan, Peng Chen, Yin-Xiao Du, Ke-Wei Zhu, Dao-Yu Zhang, Han Yan, Han Liu, Yan-Ling Liu, Shan Cao, Gan Zhou, Hui Zeng, Shu-Ping Chen, Xie-Lan Zhao, Jing Yang, Wen-Jing Zeng, Xiao-Ping Chen
Publikováno v:
Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-10 (2019)
Abstract Background The influence of DNMT3A R882 mutations on adult acute myeloid leukemia (AML) prognosis is still controversial presently. The influence of R882 allele ratio on drug response and prognosis of AML is unknown yet. Besides, it is obscu
Externí odkaz:
https://doaj.org/article/3526266a67a24d8897cd1de1478dac51
Autor:
Peng Chen, Ke-Wei Zhu, Dao-Yu Zhang, Han Yan, Han Liu, Yan-Ling Liu, Shan Cao, Gan Zhou, Hui Zeng, Shu-Ping Chen, Xie-Lan Zhao, Jing Yang, Xiao-Ping Chen
Publikováno v:
Journal of Translational Medicine, Vol 16, Iss 1, Pp 1-9 (2018)
Abstract Backgrounds UDP-glucuronosyltransferase 1A subfamily (UGT1A) enzymes can inactivate cytarabine (Ara-C) by glucuronidation, and thus serves as candidate genes for interindividual difference in Ara-C response. UGT1A1 is a major UGT1A isoform e
Externí odkaz:
https://doaj.org/article/4b2eead0902645aa85b844bbb8464ac9
Autor:
Ke-Wei Zhu, Peng Chen, Dao-Yu Zhang, Han Yan, Han Liu, Li-Na Cen, Yan-Ling Liu, Shan Cao, Gan Zhou, Hui Zeng, Shu-Ping Chen, Xie-Lan Zhao, Xiao-Ping Chen
Publikováno v:
Journal of Translational Medicine, Vol 16, Iss 1, Pp 1-14 (2018)
Abstract Background Cytarabine arabinoside (Ara-C) has been the core of chemotherapy for adult acute myeloid leukemia (AML). Ara-C undergoes a three-step phosphorylation into the active metabolite Ara-C triphosphosphate (ara-CTP). Several enzymes are
Externí odkaz:
https://doaj.org/article/f3c3f19e92ce40e2838cdefa1ca1f409
Autor:
Gan Zhou, Shu-Ping Chen, Dao-Yu Zhang, Shan Cao, Ke-Wei Zhu, Peng Chen, Yan-Ling Liu, Xie-Lan Zhao, Xiao-Ping Chen, Hui Zeng, Han Yan, Li-Na Cen, Han Liu
Publikováno v:
Journal of Translational Medicine, Vol 16, Iss 1, Pp 1-14 (2018)
Journal of Translational Medicine
Journal of Translational Medicine
Background Cytarabine arabinoside (Ara-C) has been the core of chemotherapy for adult acute myeloid leukemia (AML). Ara-C undergoes a three-step phosphorylation into the active metabolite Ara-C triphosphosphate (ara-CTP). Several enzymes are involved
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f803d98343f31952e162e38b56d1331
http://link.springer.com/article/10.1186/s12967-018-1463-1
http://link.springer.com/article/10.1186/s12967-018-1463-1
Autor:
Xie-Lan Zhao, Gan Zhou, Shu-Ping Chen, Ke-Wei Zhu, Peng Chen, Shan Cao, Jing Yang, Dao-Yu Zhang, Xiao-Ping Chen, Hui Zeng, Xiao-Qing Yuan, Yan-Ling Liu, Han Liu, Yin-Xiao Du, Han Yan, Wen-Jing Zeng
Publikováno v:
Journal of Translational Medicine
Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-10 (2019)
Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-10 (2019)
Background The influence of DNMT3A R882 mutations on adult acute myeloid leukemia (AML) prognosis is still controversial presently. The influence of R882 allele ratio on drug response and prognosis of AML is unknown yet. Besides, it is obscure whethe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cce52f68c51f8c37f6c6e5a969659a3
https://pubmed.ncbi.nlm.nih.gov/31291961
https://pubmed.ncbi.nlm.nih.gov/31291961
Autor:
Yuan, Xiao-Qing, Chen, Peng, Yin-Xiao Du, Zhu, Ke-Wei, Dao-Yu Zhang, Yan, Han, Liu, Han, Liu, Yan-Ling, Cao, Shan, Zhou, Gan, Zeng, Hui, Chen, Shu-Ping, Xie-Lan Zhao, Yang, Jing, Zeng, Wen-Jing, Chen, Xiao-Ping
Additional file 1: Table S1. Primer sequences used for detection of somatic mutation in AML. Table S2. Clinical features of AML patients according to DNMT3A R882 mutation status (supplementary). Table S3. DNMT3A R882 mutations and clinical factors of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::208bbd985736927dbe9a23a7005828cd
Autor:
Wei Zhang, Dao-Yu Zhang, Xiao-Ping Chen, Shan Cao, Hui Zeng, Xiao-Qing Yuan, Han Yan, Xiao-Lin Li
Publikováno v:
Pharmacogenomics. 17:1519-1531
Aim: DCK is a rate-limiting enzyme in cytarabine activation. rs4643786 and rs67437265 (P122S) variants are reported to affect DCK activity. Patients & methods: A total of 282 newly diagnosed acute myeloid leukemia (AML) patients were treated with cyt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e1f61486b5fa8df59f98ac98068f2d4
https://doi.org/10.2217/pgs-2016-0084
https://doi.org/10.2217/pgs-2016-0084
Autor:
Xi Li, Xiao-Ping Chen, Ji-Ye Yin, Xiao-Qing Yuan, Ke-Wei Zhu, Hui Zeng, Xiao-Lin Li, Dao-Yu Zhang, Yong-Long Yang, Yan-Hong Chen, Han Yan
Publikováno v:
Oncotarget
// Xiao-Qing Yuan 1, 2 , Dao-Yu Zhang 1, 2 , Han Yan 1, 2 , Yong-Long Yang 3 , Ke-Wei Zhu 1, 2 , Yan-Hong Chen 1, 2 , Xi Li 1, 2 , Ji-Ye Yin 1, 2 , Xiao-Lin Li 4 , Hui Zeng 4 , Xiao-Ping Chen 1, 2, 5 1 Department of Clinical Pharmacology, Xiangya Hos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56365d4c2b25a80f2121d9e8c84ba351
http://europepmc.org/articles/PMC5312402
http://europepmc.org/articles/PMC5312402
Autor:
Dao-Yu Zhang, Shu-Ping Chen, Shan Cao, Yan-Ling Liu, Han Yan, Gan Zhou, Jing Yang, Xiao-Ping Chen, Han Liu, Xie-Lan Zhao, Hui Zeng, Peng Chen, Ke-Wei Zhu
Publikováno v:
Journal of Translational Medicine
Journal of Translational Medicine, Vol 16, Iss 1, Pp 1-9 (2018)
Journal of Translational Medicine, Vol 16, Iss 1, Pp 1-9 (2018)
Backgrounds UDP-glucuronosyltransferase 1A subfamily (UGT1A) enzymes can inactivate cytarabine (Ara-C) by glucuronidation, and thus serves as candidate genes for interindividual difference in Ara-C response. UGT1A1 is a major UGT1A isoform expressed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bac1248ccdeb5666b3e81a197b7a12c8
https://pubmed.ncbi.nlm.nih.gov/30016963
https://pubmed.ncbi.nlm.nih.gov/30016963
Autor:
Chen, Peng, Zhu, Ke-Wei, Dao-Yu Zhang, Yan, Han, Liu, Han, Liu, Yan-Ling, Cao, Shan, Zhou, Gan, Zeng, Hui, Chen, Shu-Ping, Xie-Lan Zhao, Yang, Jing, Chen, Xiao-Ping
Additional file 1: Table S1. Primer sequences used to genotype UGT1A1*28 and *6.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b47880648c788b836ed72d5ccbe0c55