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Akademický článek

Hyperactivation of ATF4/TGF-β1 signaling contributes to the progressive cardiac fibrosis in Arrhythmogenic cardiomyopathy caused by DSG2 Variant

Autor: Baowei Zhang, Yizhang Wu, Chunjiang Zhou, Jiaxi Xie, Youming Zhang, Xingbo Yang, Jing Xiao, Dao Wu Wang, Congjia Shan, Xiujuan Zhou, Yaozu Xiang, Bing Yang

Publikováno v: BMC Medicine, Vol 22, Iss 1, Pp 1-23 (2024)

Abstract Background Arrhythmogenic cardiomyopathy (ACM) is an inherited cardiomyopathy characterized with progressive cardiac fibrosis and heart failure. However, the exact mechanism driving the progression of cardiac fibrosis and heart failure in AC

Externí odkaz: https://doaj.org/article/d7914032d6aa4b56bc12cd2bfab1e3a7

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Akademický článek

Clinical characteristics and therapeutic strategy of frequent accelerated idioventricular rhythm

Autor: Lan Wang, Hailei Liu, Chao Zhu, Kai Gu, Gang Yang, Hongwu Chen, Weizhu Ju, Mingfang Li, Fengxiang Zhang, Bing Yang, Dao Wu Wang, Minglong Chen

Publikováno v: BMC Cardiovascular Disorders, Vol 21, Iss 1, Pp 1-9 (2021)

Abstract Background Accelerated idioventricular rhythm (AIVR) is often transient, considered benign and requires no treatment. This observational study aims to investigate the clinical manifestations, treatment, and prognosis of frequent AIVR. Method

Externí odkaz: https://doaj.org/article/8f5952bc137241dfbff871efe02f167c

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Akademický článek

2020 APHRS/HRS expert consensus statement on the investigation of decedents with sudden unexplained death and patients with sudden cardiac arrest, and of their families

Publikováno v: Journal of Arrhythmia, Vol 37, Iss 3, Pp 481-534 (2021)

Abstract This international multidisciplinary document intends to provide clinicians with evidence‐based practical patient‐centered recommendations for evaluating patients and decedents with (aborted) sudden cardiac arrest and their families. The

Externí odkaz: https://doaj.org/article/c178f64f2c6147188a7773debe130bba

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Akademický článek

Whole-exome sequencing identifies a de novo PDE3A variant causing autosomal dominant hypertension with brachydactyly type E syndrome: a case report

Autor: Xianqing Li, Zongzhe Li, Peng Chen, Yan Wang, Dao Wen Wang, Dao Wu Wang

Publikováno v: BMC Medical Genetics, Vol 21, Iss 1, Pp 1-6 (2020)

Abstract Background Autosomal dominant hypertension with brachydactyly type E syndrome caused by pathogenic variants in the PDE3A gene was first reported in 2015. To date, there are only a few reports of this kind of syndrome. Other patients still la

Externí odkaz: https://doaj.org/article/df520cb3ca85499db112c9f7acffc710

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Akademický článek

Association of the Number of Embryos Transferred with Ectopic Pregnancy after Embryo Transfer in Patients with Salpingectomy or Proximal Tubal Occlusion

Autor: Caihe Wen, Yuan Zhang, Xinru Xia, Xiang Ma, Yundong Mao, Dao Wu Wang, Jiayin Liu

Publikováno v: Clinical and Experimental Obstetrics & Gynecology, Vol 49, Iss 9, p 196 (2022)

Background: With the prevalence of assisted reproductive technology (ART), the incidence of ectopic pregnancy (EP) is increasing, especially in patients with salpingectomy or proximal tubal occlusion. Methods: A total of 11,609 women who were undergo

Externí odkaz: https://doaj.org/article/da2ca787410c451ca6871359edba6ae7

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Akademický článek

Knockout of SORBS2 Protein Disrupts the Structural Integrity of Intercalated Disc and Manifests Features of Arrhythmogenic Cardiomyopathy

Autor: Yonghe Ding, Jingchun Yang, Peng Chen, Tong Lu, Kunli Jiao, David J. Tester, John R. Giudicessi, Kai Jiang, Michael J. Ackerman, Yigang Li, Dao Wu Wang, HoN‐chi Lee, Dao Wen Wang, Xiaolei Xu

Publikováno v: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 17 (2020)

Background Sorbs2b (sorbin and SH3 domain‐containing 2b) was recently identified as a cardiomyopathy gene from a zebrafish mutagenesis screen. However, cardiac functions of its mammalian ortholog remain elusive. Methods and Results We conducted a d

Externí odkaz: https://doaj.org/article/af816d412d974fd3a6b29b8743241fc1

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2020 APHRS/HRS expert consensus statement on the investigation of decedents with sudden unexplained death and patients with sudden cardiac arrest, and of their families

Publikováno v: Journal of Arrhythmia
Stiles, M K, Wilde, A A M, Abrams, D J, Ackerman, M J, Albert, C M, Behr, E R, Chugh, S S, Cornel, M C, Gardner, K, Ingles, J, James, C A, Juang, J-M J, Kääb, S, Kaufman, E S, Krahn, A D, Lubitz, S A, MacLeod, H, Morillo, C A, Nademanee, K, Probst, V, Saarel, E V, Sacilotto, L, Semsarian, C, Sheppard, M N, Shimizu, W, Skinner, J R, Tfelt-Hansen, J & Wang, D W 2021, ' 2020 APHRS/HRS expert consensus statement on the investigation of decedents with sudden unexplained death and patients with sudden cardiac arrest, and of their families ', Journal of Arrhythmia, vol. 37, no. 3, pp. 481-534 . https://doi.org/10.1002/joa3.12449
Journal of Arrhythmia, Vol 37, Iss 3, Pp 481-534 (2021)
Heart rhythm, 18(1), e1-e50. Elsevier
Journal of arrhythmia, 37(3), 481-534. John Wiley & Sons Inc.
Stiles, M K, Wilde, A A M, Abrams, D J, Ackerman, M J, Albert, C M, Behr, E R, Chugh, S S, Cornel, M C, Gardner, K, Ingles, J, James, C A, Juang, J-M J, Kääb, S, Kaufman, E S, Krahn, A D, Lubitz, S A, MacLeod, H, Morillo, C A, Nademanee, K, Probst, V, Saarel, E V, Sacilotto, L, Semsarian, C, Sheppard, M N, Shimizu, W, Skinner, J R, Tfelt-Hansen, J & Wang, D W 2021, ' 2020 APHRS/HRS expert consensus statement on the investigation of decedents with sudden unexplained death and patients with sudden cardiac arrest, and of their families ', Journal of arrhythmia, vol. 37, no. 3, pp. 481-534 . https://doi.org/10.1002/joa3.12449
Heart Rhythm, 18(1), e1-e50. Elsevier
Heart rhythm
Stiles, M K, Wilde, A A M, Abrams, D J, Ackerman, M J, Albert, C M, Behr, E R, Chugh, S S, Cornel, M C, Gardner, K, Grad, J I, James, C A, Jimmy Juang, J-M, Kääb, S, Kaufman, E S, Krahn, A D, Lubitz, S A, MacLeod, H, Morillo, C A, Nademanee, K, Probst, V, Saarel, E V, Sacilotto, L, Semsarian, C, Sheppard, M N, Shimizu, W, Skinner, J R, Tfelt-Hansen, J, Wang, D W & Document Reviewers 2021, ' 2020 APHRS/HRS expert consensus statement on the investigation of decedents with sudden unexplained death and patients with sudden cardiac arrest, and of their families ', Heart Rhythm, vol. 18, no. 1, pp. e1-e50 . https://doi.org/10.1016/j.hrthm.2020.10.010
Journal of arrhythmia, 37(3), 481-534. Elsevier BV
Document Reviewers 2021, ' 2020 APHRS/HRS Expert Consensus Statement on the Investigation of Decedents with Sudden Unexplained Death and Patients with Sudden Cardiac Arrest, and of Their Families ', Heart Rhythm, vol. 18, no. 1 . https://doi.org/10.1016/j.hrthm.2020.10.010

This international multidisciplinary document intends to provide clinicians with evidence‐based practical patient‐centered recommendations for evaluating patients and decedents with (aborted) sudden cardiac arrest and their families. The document

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e4e45982c15bad1f41589e18e4a24d1
http://europepmc.org/articles/PMC8207384

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Majority of transferred mosaic embryos developed healthy live births revealed by a preclinical study using embryonic morphology assessment and noninvasive PGT-A on cell-free DNA in blastocoel fluid

Autor: Lingbo Cai, Qiao Zeng, Chao Gao, Wei Wu, Jiandong Shen, Bai-Lin Wu, Dao Wu Wang, Yugui Cui, Jiayin Liu

Publikováno v: Journal of assisted reproduction and genetics. 39(11)

This preclinical study aimed to evaluate whether using transferred mosaic embryos (primarily selected by embryonic morphology assessment (EMA) and compared by the noninvasive preimplantation genetic testing for aneuploidy (niPGT-A) on cell-free DNA i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c493b1c2858c8c8070e9e45c9c509b22
https://pubmed.ncbi.nlm.nih.gov/36422765

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Genetic arrhythmias complicating patients with dilated cardiomyopathy

Autor: Dao Wu Wang, Chenze Li, Dao Wen Wang, Arthur A.M. Wilde, Yan Wang, Peng Chen, Jinchao Xu, Lun Tan, Mark S. Link, Chunxia Zhao, Hong Wang, Zongzhe Li, Yang Sun

Publikováno v: Heart rhythm, 17(2), 305-312. Elsevier

Background Sudden cardiac death due to malignant arrhythmias is a common cause of death in dilated cardiomyopathy (DCM). Whether genetic variants increase the risk of arrhythmias in DCM is unknown. Objective The purpose of this study was to investiga

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55eae75c86e519ca97d1bf39cb06b773
https://doi.org/10.1016/j.hrthm.2019.09.012

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