Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Danyi, Wang"'
Autor:
Danyi Wang, Deqiao Sun, Xiaoyan Wang, Xia Peng, Yinchun Ji, Lu Tang, Qichang He, Danqi Chen, Ye Yang, Xuan Zhou, Bing Xiong, Jing Ai
Publikováno v:
MedComm, Vol 5, Iss 7, Pp n/a-n/a (2024)
Abstract Mitogen‐activated protein kinase‐activated protein kinase 2 (MK2) emerges as a pivotal target in developing anti‐cancer therapies. The limitations of ATP‐competitive inhibitors, due to insufficient potency and selectivity, underscore
Externí odkaz:
https://doaj.org/article/625b4ce35fc9407796898ac8892c510c
Autor:
Jason Gorman, Crystal Sao-Fong Cheung, Zhijian Duan, Li Ou, Maple Wang, Xuejun Chen, Cheng Cheng, Andrea Biju, Yaping Sun, Pengfei Wang, Yongping Yang, Baoshan Zhang, Jeffrey C. Boyington, Tatsiana Bylund, Sam Charaf, Steven J. Chen, Haijuan Du, Amy R. Henry, Tracy Liu, Edward K. Sarfo, Chaim A. Schramm, Chen-Hsiang Shen, Tyler Stephens, I-Ting Teng, John-Paul Todd, Yaroslav Tsybovsky, Raffaello Verardi, Danyi Wang, Shuishu Wang, Zhantong Wang, Cheng-Yan Zheng, Tongqing Zhou, Daniel C. Douek, John R. Mascola, David D. Ho, Mitchell Ho, Peter D. Kwong
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Lassa virus (LASV) infection is expanding outside its traditionally endemic areas in West Africa, posing a pandemic biothreat. LASV-neutralizing antibodies, moreover, have proven difficult to elicit. To gain insight into LASV neutralization,
Externí odkaz:
https://doaj.org/article/83f13599c74f445ebfcd24f0985fef96
Autor:
Danyi Wang, Xuesong Bo
Publikováno v:
Sport TK, Vol 13 (2024)
Article accepted. The article will be published here soon. Pending final quality checks.
Externí odkaz:
https://doaj.org/article/d6d2b3313f744f99979f7b5c1f628450
Autor:
Feifei Fang, Yang Dai, Hao Wang, Yinchun Ji, Xuewu Liang, Xia Peng, Jiyuan Li, Yangrong Zhao, Chunpu Li, Danyi Wang, Yazhou Li, Dong Zhang, Dan Zhang, Meiyu Geng, Hong Liu, Jing Ai, Yu Zhou
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 13, Iss 12, Pp 4918-4933 (2023)
As a novel and promising antitumor target, AXL plays an important role in tumor growth, metastasis, immunosuppression and drug resistance of various malignancies, which has attracted extensive research interest in recent years. In this study, by empl
Externí odkaz:
https://doaj.org/article/d516c2f765514631b7bf774badc1f3ce
Autor:
Danyi Wang, Brian Elenbaas, Karthikeyan Murugesan, Kunal Shah, Meagan Montesion, Ioannis Gounaris, Juergen Scheuenpflug, Giuseppe Locatelli, Zheng Feng
Publikováno v:
npj Precision Oncology, Vol 7, Iss 1, Pp 1-14 (2023)
Abstract The DNA damage response (DDR) pathway regulates DNA repair and cell survival, and inactivating mutations in DDR genes can increase tumour mutational burden (TMB), a predictive biomarker of treatment benefit from anti-PD-1/PD-L1 immunotherapi
Externí odkaz:
https://doaj.org/article/2ded5998f24843ed9b46f8053f3b125a
Autor:
Danyi Wang, Javaan Chahl
Publikováno v:
Frontiers in Robotics and AI, Vol 10 (2024)
Introduction: Image-based heart rate estimation technology offers a contactless approach to healthcare monitoring that could improve the lives of millions of people. In order to comprehensively test or optimize image-based heart rate extraction metho
Externí odkaz:
https://doaj.org/article/83ce4314943740f8a3fbef3e6cc600ae
Autor:
Shuishu Wang, Flavio Matassoli, Baoshan Zhang, Tracy Liu, Chen-Hsiang Shen, Tatsiana Bylund, Timothy Johnston, Amy R. Henry, I-Ting Teng, Prabhanshu Tripathi, Jordan E. Becker, Anita Changela, Ridhi Chaudhary, Cheng Cheng, Martin Gaudinski, Jason Gorman, Darcy R. Harris, Myungjin Lee, Nicholas C. Morano, Laura Novik, Sijy O’Dell, Adam S. Olia, Danealle K. Parchment, Reda Rawi, Jesmine Roberts-Torres, Tyler Stephens, Yaroslav Tsybovsky, Danyi Wang, David J. Van Wazer, Tongqing Zhou, Nicole A. Doria-Rose, Richard A. Koup, Lawrence Shapiro, Daniel C. Douek, Adrian B. McDermott, Peter D. Kwong
Publikováno v:
Cell Reports, Vol 42, Iss 7, Pp 112755- (2023)
Summary: Elicitation of antibodies that neutralize the tier-2 neutralization-resistant isolates that typify HIV-1 transmission has been a long-sought goal. Success with prefusion-stabilized envelope trimers eliciting autologous neutralizing antibodie
Externí odkaz:
https://doaj.org/article/bb8a5ffea19d425c87466117bf7a3b5c
Autor:
Zhantong Wang, Baoshan Zhang, Li Ou, Qi Qiu, Lingshu Wang, Tatsiana Bylund, Wing-Pui Kong, Wei Shi, Yaroslav Tsybovsky, Lingyuan Wu, Qiong Zhou, Ridhi Chaudhary, Misook Choe, Thayne H. Dickey, Mohammed El Anbari, Adam S. Olia, Reda Rawi, I-Ting Teng, Danyi Wang, Shuishu Wang, Niraj H. Tolia, Tongqing Zhou, Peter D. Kwong
Publikováno v:
Vaccines, Vol 12, Iss 1, p 37 (2023)
The receptor-binding domain (RBD) of the SARS-CoV-2 spike is a primary target of neutralizing antibodies and a key component of licensed vaccines. Substantial mutations in RBD, however, enable current variants to escape immunogenicity generated by va
Externí odkaz:
https://doaj.org/article/5a6e533b068544d5a92eea9c86896ad3
Autor:
Danyi Wang, Dennis O’Rourke, Jorge F. Sanchez-Garcia, Ti Cai, Juergen Scheuenpflug, Zheng Feng
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-10 (2021)
Abstract Background MutL Homolog 1 (MLH1) promotor methylation is associated with microsatellite instability high colorectal cancer (CRC). The strong correlation between methylation status and cancer development and progression has led to a growing i
Externí odkaz:
https://doaj.org/article/cdcef17b668c499fa74247605b92d156
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Multimodality therapy including surgical resection is the current paradigm in treating malignant pleural mesothelioma (MPM), a thoracic surface cancer without cure. The main limitation of all surgical approaches is the lack of long-term durability be
Externí odkaz:
https://doaj.org/article/bd35d1f7b3c746d0897d30c15b6ff4c0