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Akademický článek

The influence of pterygium on corneal densitometry evaluated using the Oculus Pentacam system

Autor: Jing Zhang, Liyun Zhang, Huiling Hu, Liangnan Sun, Wenling He, Zhe Zhang, Jiantao Wang, Danyao Nie, Xinhua Liu

Publikováno v: Frontiers in Medicine, Vol 10 (2023)

PurposeTo assess the effect of pterygium on corneal densitometry (CD) values.MethodsOne hundred and nine patients (155 eyes) with primary pterygium were divided into a severe pterygium group (79 eyes) and a mild-to-moderate pterygium group (76 eyes)

Externí odkaz: https://doaj.org/article/f92f081346f0408eb5ec227879ab18b1

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Akademický článek

In vivo confocal microscopy qualitative investigation of the relationships between lattice corneal dystrophy deposition and corneal nerves

Autor: Fengjiao Zhu, Ming Li, Chun Zhang, Chan Chen, Fangwei Ying, Danyao Nie

Publikováno v: BMC Ophthalmology, Vol 21, Iss 1, Pp 1-10 (2021)

Abstract Background To investigate the corneal neurotropic phenomenon in patients with lattice corneal dystrophy (LCD) with in vivo laser scanning confocal microscopy (IVCM). Methods IVCM was performed on a total of 15 patients (28 eyes) with LCD ann

Externí odkaz: https://doaj.org/article/88f038669f024f4b97229e3381617712

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Akademický článek

Case report: Biochemical and clinical phenotypes caused by cysteine substitutions in the epidermal growth factor-like domains of fibrillin-1

Autor: Xin Liu, Kaiqing Liu, Danyao Nie, Jing Zhang, Liyun Zhang, Xinhua Liu, Jiantao Wang

Publikováno v: Frontiers in Genetics, Vol 13 (2022)

Marfan syndrome, an autosomal dominant disorder of connective tissue, is primarily caused by mutations in the fibrillin-1 (FBN1) gene, which encodes the protein fibrillin-1. The protein is composed of epidermal growth factor-like (EGF-like) domains,

Externí odkaz: https://doaj.org/article/71d8b649b033408a875a006ef45efb2e

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Akademický článek

RNA-seq analysis reveals differentially expressed inflammatory chemokines in a rat retinal degeneration model induced by sodium iodate

Autor: Sheng Chen, Guo Liu, Xin Liu, Yun Wang, Fen He, Danyao Nie, Xinhua Liu, Xuyang Liu

Publikováno v: Journal of International Medical Research, Vol 50 (2022)

Objective Retinal degeneration (RD) is a group of serious blinding eye diseases characterized by photoreceptor cell apoptosis and progressive degeneration of retinal neurons. However, the underlying mechanism of its pathogenesis remains unclear. Meth

Externí odkaz: https://doaj.org/article/e34b3561fc42440c839b55c74350bfeb

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Akademický článek

Deep learning from 'passive feeding' to 'selective eating' of real-world data

Autor: Zhongwen Li, Chong Guo, Danyao Nie, Duoru Lin, Yi Zhu, Chuan Chen, Lanqin Zhao, Xiaohang Wu, Meimei Dongye, Fabao Xu, Chenjin Jin, Ping Zhang, Yu Han, Pisong Yan, Haotian Lin

Publikováno v: npj Digital Medicine, Vol 3, Iss 1, Pp 1-9 (2020)

Abstract Artificial intelligence (AI) based on deep learning has shown excellent diagnostic performance in detecting various diseases with good-quality clinical images. Recently, AI diagnostic systems developed from ultra-widefield fundus (UWF) image

Externí odkaz: https://doaj.org/article/055ceb8e611d4d64b7457405ba2cacfa

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Akademický článek

Comparative Transcriptomic Analysis to Identify the Important Coding and Non-coding RNAs Involved in the Pathogenesis of Pterygium

Autor: Xin Liu, Jing Zhang, Danyao Nie, Kun Zeng, Huiling Hu, Jinjun Tie, Liangnan Sun, Ling Peng, Xinhua Liu, Jiantao Wang

Publikováno v: Frontiers in Genetics, Vol 12 (2021)

Pterygium is a common ocular surface disease characterized by abnormal fibrovascular proliferation and invasion, similar to tumorigenesis. The formation of tumors is related to a change in the expression of various RNAs; however, whether they are inv

Externí odkaz: https://doaj.org/article/f61ce37b36dc4fd9af6071d56b548373

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Akademický článek

Polymorphisms and Circulating Plasma Protein Levels of Immune Checkpoints (CTLA-4 and PD-1) Are Associated With Posner-Schlossman Syndrome in Southern Chinese

Autor: Xiaosheng Huang, Xinhua Liu, Ye Ye, Tong Zhang, Shaoyi Mei, Tianhui Zhu, Shiming Peng, Jiamin Cai, Zonghui Yan, Kun Zeng, Danyao Nie, Liangnan Sun, Xiaofeng Hou, Jun Zhao

Publikováno v: Frontiers in Immunology, Vol 12 (2021)

Cytotoxic T-lymphocyte associated protein 4 (CTLA-4) and programmed cell death 1 (PD-1) are well-known key immune checkpoints that play a crucial dampening effect on regulating T-cell homeostasis and self-tolerance. In this study, we aimed to evaluat

Externí odkaz: https://doaj.org/article/f33cd66da19643739981a8a83e91b52a

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Akademický článek

Knockdown of MALAT1 attenuates high-glucose-induced angiogenesis and inflammation via endoplasmic reticulum stress in human retinal vascular endothelial cells

Autor: Yuan Wang, Ling Wang, Hui Guo, Yun Peng, Danyao Nie, Jinsong Mo, Lin Ye

Publikováno v: Biomedicine & Pharmacotherapy, Vol 124, Iss , Pp 109699- (2020)

Diabetic retinopathy (DR) is one of the most severe complications of diabetes mellitus, and retinal endoplasmic reticulum stress (ERS) plays an important role in the pathogenesis of DR. However, the exact mechanisms by which ERS mediates DR remain un

Externí odkaz: https://doaj.org/article/c75e7f22951148218c77e71de9859239

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