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pro vyhledávání: '"Dany Desjardins"'
Autor:
Jacques Jean-François, Benoît Métayer, Luc H. Boudreau, Dany Desjardins, Natalie A. Levesque, Samuel J. Poirier, Jérémie A. Doiron, Mohamed Touaibia, Marc E. Surette, Ryan Richard
Publikováno v:
International Journal of Medicinal Chemistry, Vol 2014 (2014)
International Journal of Medicinal Chemistry
International Journal of Medicinal Chemistry
5-Lipoxygenase (5-LO) is the key enzyme responsible for the conversion of arachidonic acid to leukotrienes, a class of lipid mediators implicated in inflammatory disorders. In this paper, we describe the design, synthesis, and preliminary activity st