Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Dany Arsenault"'
Publikováno v:
Biology of Sex Differences, Vol 11, Iss 1, Pp 1-19 (2020)
Abstract While the higher prevalence of Alzheimer’s disease (AD) in women is clear, studies suggest that biological sex may also influence AD pathogenesis. However, mechanisms behind these differences are not clear. To investigate physiological dif
Externí odkaz:
https://doaj.org/article/6942848ad44648d49e14473b8bb15037
Autor:
Dany Arsenault, Katherine Coulombe, Aijun Zhu, Chunyu Gong, Kun-Eek Kil, Ji-Kyung Choi, Pekka Poutiainen, Anna-Liisa Brownell
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0142093 (2015)
Parental microglial induced neuroinflammation, triggered by bacterial- or viral infections, can induce neuropsychiatric disorders like schizophrenia and autism to offspring in animal models. Recent investigations suggest that microglia, the resident
Externí odkaz:
https://doaj.org/article/fdbccad48b534a6bb5844e49177ec34a
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e17397 (2011)
Defects in neuronal activity of the entorhinal cortex (EC) are suspected to underlie the symptoms of Alzheimer's disease (AD). Whereas neuroprotective effects of docosahexaenoic acid (DHA) have been described, the effects of DHA on the physiology of
Externí odkaz:
https://doaj.org/article/6703e8716ee7403c941f35570ea0597f
Autor:
Jasna Kriz, Marilyn Dubois, Dany Arsenault, Antonio Cicchetti, Martine Saint-Pierre, Francesca Cicchetti, Benoit Aubé, Melanie Alpaugh
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Deep brain stimulation (DBS) has been used in clinical settings for many years despite a paucity of knowledge related to the anatomical and functional substrates that lead to benefits and/or side-effects in various disease contexts. In order to maxim
Autor:
Janelle Drouin-Ouellet, Jasna Kriz, Antonio Cicchetti, Francesca Cicchetti, Marilyn Dubois, Martine Saint-Pierre, Roger A. Barker, Dany Arsenault, Petros Petrou
Publikováno v:
The Journal of Physiology. 593:2257-2278
Deep brain stimulation (DBS) is used to treat a number of neurological conditions and is currently being tested to intervene in neuropsychiatric conditions. However, a better understanding of how it works would ensure that side effects could be minim
Autor:
Frédéric Calon, Cyril Bories, Yves De Koninck, Cyntia Tremblay, Dany Arsenault, Myriam Lemire
Publikováno v:
Aging (Albany NY)
Defects in p21-activated kinase (PAK) lead to dendritic spine abnormalities and are sufficient to cause cognition impairment. The decrease in PAK in the brain of Alzheimer's disease (AD) patients is suspected to underlie synaptic and dendritic distur
Autor:
Anna-Liisa Brownell, Kun-Eek Kil, Sreekanth Kura, Dany Arsenault, Ji-Kyung Choi, Chunyu Gong, Aijun Zhu
Publikováno v:
Open Journal of Medical Psychology. :202-211
Many studies have reported long-term modulation of metabotropic glutamate receptor 5 (mGluR5) by inflammatory processes and a pharmacological modulation of mGluR5 is known to regulate anxiety level. However, it is not known if non-pharmacological mod
Publikováno v:
Journal of Neurochemistry. 122:427-443
Dietary lipids modify brain fatty acid profile, but evidence of their direct effect on neuronal function is sparse. The enthorinal cortex (EC) neurons connecting to the hippocampus play a critical role in learning and memory. Here, we have exposed mi
Autor:
Zhong-wei Zhang, Dany Arsenault
Publikováno v:
The Journal of Physiology. 573:121-132
Synapse elimination occurs throughout the nervous system during development, and is essential for the formation of neural circuits. The mechanisms underlying synapse elimination in the brain, however, remain largely unknown. Using whole-cell patch-cl
Autor:
Zhong-wei Zhang, Dany Arsenault
Publikováno v:
The Journal of Physiology. 566:379-394
Serotonin (5-HT) is widely implicated in brain functions and diseases. The vertebrate brain is extensively innervated by 5-HT fibres originating from the brain stem, and 5-HT axon terminals interact with other neurones in complex ways. The cellular m