Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Danuta Tracz"'
Autor:
Leonid Beigelman, Alexander Karpeisky, James McSwiggen, Varykina G. Thackray, Kristi Jensen, Francine E. Wincott, Nassim Usman, Jasenka Matulic-Adamic, Kenneth G. Draper, Danuta Tracz, David Sweedler, Anil S. Modak, Carolyn Gonzalez, Susan Grimm, Peter Haeberli, Anthony DiRenzo
Publikováno v:
Journal of Biological Chemistry. 270:25702-25708
A systematic study of selectively modified, 36-mer hammerhead ribozymes has resulted in the identification of a generic, catalytically active and nuclease stable ribozyme motif containing 5 ribose residues, 29-30 2'-O-Me nucleotides, 1-2 other 2'-mod
Autor:
Francine Wincott, Anthony DiRenzo, Chris Shaffer, Susan Grimm, Danuta Tracz, Christopher Workman, David Sweedler, Carolyn Gonzalez, Stephen Scaringe, Nassim Usman
Publikováno v:
Nucleic Acids Research. 23:2677-2684
Improvements in the synthesis, deprotection and purification of oligoribonucleotides are described. These advances allow for reduced synthesis and deprotection times, while improving product yield. Coupling times are reduced by half using 5-ethylthio