Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Danuta Pawlak"'
Autor:
Marco Crisma, Jacek Pelka, Danuta Pawlak, Giovanni Valle, Claudio Toniolo, Conrad H. Schneider, V. Moretto, Gian Maria Bonora, Jan Izdebski
Publikováno v:
International Journal of Peptide and Protein Research. 31:77-85
An X-ray diffraction study has been carried out on single crystals of two symmetrical ureines (N,N′-diiopropylurea and the familiar N,N′-dicyclohexylurea) and one unsymmetrical ureine (N-tert.-butyl.N′-methylurea). The presence/absence of inter
Autor:
Agnieszka Parcińska, Marta Oleszczuk, Katarzyna Filip, Jan Izdebski, Nga N. Chung, Jacek Wójcik, Danuta Pawlak, Agnieszka Zieleniak, Ewa Witkowska, Peter W. Schiller
Publikováno v:
Journal of Peptide Science. 11:347-352
Four cyclic enkephalin analogues and four cyclic dermorphin analogues have been synthesized. Cyclization of linear peptides containing basic amino acid residues of various side chain length in position 2 and 5 (enkephalin analogues) or 2 and 4 (dermo
Publikováno v:
European Journal of Pharmacology. 496:167-174
Investigation of the acute cardiovascular and renal effects of cyclo[Nepsilon,Nbeta-carbonyl-D-Lys2,Dap5]enkephalinamide (cUENK6), the most potent mu-opioid receptor agonist, revealed dose-related effects, but most pronounced during the first hour po
Autor:
Nga N. Chung, Danuta Pawlak, Marta Oleszczuk, Peter W. Schiller, Jan Izdebski, Jacek Wójcik, Katarzyna Filip
Publikováno v:
Journal of Peptide Science. 9:649-657
A new family of cyclic opioid peptide analogues related to the 1-4 sequence of dermor- phin/deltorphin (Tyr-D-Aaa 2 -Phe-Aaa 4 -NH2) has been synthesized. The synthesis of the linear precursor peptides was accomplished by the solid-phase method and r
Autor:
Jacek Wójcik, Nga N. Chung, Jan Izdebski, Maria Pachulska, Danuta Pawlak, Peter W. Schiller, Marta Oleszczuk
Publikováno v:
Journal of Peptide Science. 7:128-140
Six novel cyclic enkephalin analogues have been synthesized. Cyclization of the linear peptides containing basic amino acid residues in position 2 and 5 was achieved by treatment with bis(4-nitrophenyl)carbonate. It was found that some of the compoun
Publikováno v:
ResearcherID
Conformational space of a novel cyclic enkephalin analogue, cyclo(N(epsilon),N(epsilon')-carbonyl-D-Lys2,Lys5)enkephalin amide, was exhaustively examined. A large number of conformations was selected and clustered into families on the basis of their
Publikováno v:
Journal of Peptide Science. 3:277-281
A novel type of cyclic opioid peptide analogue, cyclo[N epsilon,N epsilon'-carbonyl-D-Lys2,Lys5]enkephalinamide, was prepared from a linear precursor peptide. The peptide was synthesized on the Merrified resin and also by a combination of the solid-p
Autor:
Katarzyna, Filip, Marta, Oleszczuk, Danuta, Pawlak, Jacek, Wojcik, Nga N, Chung, Peter W, Schillerc, Jan, Izdebski
Publikováno v:
Journal of peptide science : an official publication of the European Peptide Society. 9(10)
A new family of cyclic opioid peptide analogues related to the 1-4 sequence of dermorphin/deltorphin (Tyr-D-Aaa2-Phe-Aaa4-NH2) has been synthesized. The synthesis of the linear precursor peptides was accomplished by the solid-phase method and ring fo
Autor:
Slavomir Filipek, Danuta Pawlak
Publikováno v:
Molecular Modeling and Prediction of Bioactivity ISBN: 9781461368571
Our ability to use rational design for the generation of useful peptides is depends on our ability to determine the specific relationships of molecular structure to biological activity. Opiates and opioid peptides display a large spectrum of biologic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f528dfec4d6c2585fe73d0fa3aee987d
https://doi.org/10.1007/978-1-4615-4141-7_22
https://doi.org/10.1007/978-1-4615-4141-7_22
Autor:
Jan lzdebski, Danuta Pawlak
Publikováno v:
Synthesis. 1989:423-425