Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Danuta Lisiecka"'
Minocycline for negative symptoms of schizophrenia and possible mechanistic actions: the BeneMin RCT
Autor:
Bill Deakin, John Suckling, Paola Dazzan, Eileen Joyce, Stephen M Lawrie, Rachel Upthegrove, Nusrat Husain, Imran B Chaudhry, Graham Dunn, Peter B Jones, Danuta Lisiecka-Ford, Shôn Lewis, Thomas RE Barnes, Steven CR Williams, Carmine M Pariante, Emma Knox, Richard J Drake, Richard Smallman, Nicholas M Barnes
Publikováno v:
Efficacy and Mechanism Evaluation, Vol 6, Iss 7 (2019)
Background: In a previous trial we reported that the neuroprotective, anti-inflammatory antibiotic minocycline lessened the negative symptoms of schizophrenia compared with placebo over 1 year. The BeneMin study aimed to replicate this benefit and to
Externí odkaz:
https://doaj.org/article/0626a27c0f1a4871b10da8417d20fe55
Autor:
Thomas Frodl, Angela Carballedo, Danuta Lisiecka, Derek W. Morris, John Suckling, Andrew J. Fagan, Erik O'Hanlon
Publikováno v:
Journal of Affective Disorders. 184:239-244
Background Rs6265 single nucleotide polymorphism, which influences brain-derived neurotrophic factor (BDNF) levels in the cortical and subcortical brain structures, may result in distinguished patterns of neural activation during a major depressive d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18f8a9650081d0c81d90f80cd461e854
https://doi.org/10.1016/j.jad.2015.06.002
https://doi.org/10.1016/j.jad.2015.06.002
Autor:
Yolande Ferguson, Angella Carballedo, Danuta Lisiecka, Thomas Frodl, James F. Meaney, Andrew J. Fagan
Publikováno v:
Journal of Psychiatry & Neuroscience. 38:117-128
Background: Family history of major depressive disorder (MDD) increases individuals’ vulnerability to depression and alters the way de pression manifests itself. Emotion processing and attention shifting are functions altered by MDD and family hist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14f448fd65e908dbe76d8d53359a0b2c
https://doi.org/10.1503/jpn.110188
https://doi.org/10.1503/jpn.110188
Autor:
Angela Carballedo, Thomas Frodl, Derek W. Morris, Michael Gill, Danuta Lisiecka, James F. Meaney, Ciara Fahey, Gary Donohoe, Rachel Bermingham, Andrew J. Fagan
Publikováno v:
Neuropsychopharmacology. 37:2855-2862
Genes and early-life adversity (ELA) interactively increase the risk of developing major depressive disorder (MDD). A recent genome-wide association study suggests that the minor T-allele of single-nucleotide polymorphisms in the bicaudal C homolog 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d49cf607782e079125d92f56436db859
https://doi.org/10.1038/npp.2012.158
https://doi.org/10.1038/npp.2012.158
Autor:
Andrew J. Fagan, Thomas Frodl, Angela Carballedo, James F. Meaney, Gerald Connolly, Danuta Lisiecka
Publikováno v:
Journal of Psychiatric Research. 46:181-188
Unaffected 1st degree relatives of patients with major depressive disorder (MDD) are more likely to develop MDD than healthy controls. The aim of our study was to establish neuronal correlates of familial susceptibility in the process of inhibition o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b02041e17fe7958c3e5835ce0d41bf8
https://doi.org/10.1016/j.jpsychires.2011.10.010
https://doi.org/10.1016/j.jpsychires.2011.10.010
Autor:
Thomas Frodl, Yolande Ferguson, Angela Carballedo, James F. Meaney, Andrew J. Fagan, Danuta Lisiecka
Publikováno v:
Journal of Psychiatry and Neuroscience. 37:37-45
Background: Relatives of patients with major depressive disorder (MDD) and people who experienced early-life adversity are at risk for MDD. The aim of our study was to investigate whether unaffected first-degree healthy relatives (UHRs) of patients w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddc667f5c218512d8f9bcaa78dbe1e8f
https://doi.org/10.1503/jpn.110028
https://doi.org/10.1503/jpn.110028
Publikováno v:
Perception. 41:757-773
Auditory stimuli are known to improve visual target recognition and detection when both are presented in the same spatial location. However, most studies have focused on crossmodal spatial congruency along the horizontal plane and the effects of audi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50be55baee0f857dae6d02c63963dfbd
https://doi.org/10.1068/p7230
https://doi.org/10.1068/p7230
Autor:
Richard Drake, Emma Knox, Shôn Lewis, Richard Smallman, Stephen R. Williams, Andrew J. Watson, Thomas R. E. Barnes, Graham Dunn, Eileen M. Joyce, John Suckling, Rachel Upthegrove, Stephen M. Lawrie, Paola Dazzan, Danuta Lisiecka, Bill Deakin, Peter G. Jones, Stephen J. Hopkins, Imran B Chaudhry, Kelly Byrne, Nusrat Husain
Publikováno v:
Schizophrenia Bulletin
Background Variable outcomes following a first-episode of psychosis are partly attributable to heterogeneity in cognitive functioning. Previous work in first episode psychosis has identified clinically meaningful cognitive sub-types based on pre-spec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b8cb00663d4dae110303881b4cef2ca
http://europepmc.org/articles/PMC5888601
http://europepmc.org/articles/PMC5888601
Autor:
Annalisa Giordano, Graham Dunn, Shôn Lewis, Rachel Upthegrove, Nusrat Husain, Thomas R. E. Barnes, Richard Drake, Stephen M. Lawrie, John Suckling, Carl R Krynicki, Stephen R. Williams, Peter G. Jones, Imran B Chaudhry, Carmine M. Pariante, Paola Dazzan, Stephen J. Hopkins, Danuta Lisiecka, Bill Deakin, Eileen M. Joyce, Richard Smallman
Publikováno v:
Schizophrenia Bulletin
Background Negative symptoms consist of impaired quality of life, social isolation, reduced emotional responsiveness, self-neglect and anhedonia, which have been categorised into avolition-apathy and expressive deficits sub-domains. The treatment of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9c247e11bd934a5700bcbb64cf10666
https://doi.org/10.1093/schbul/sby016.322
https://doi.org/10.1093/schbul/sby016.322
Functional Connectivity Bias of the Orbitofrontal Cortex in Drug-Free Patients with Major Depression
Autor:
Harald Hampel, Eva M. Meisenzahl, Martin Wiesmann, Hartmut Brückmann, Johanna Scheuerecker, Veronika Schoepf, Hans-Jürgen Möller, Thomas Frodl, Arun L.W. Bokde, Danuta Lisiecka
Publikováno v:
Biological Psychiatry. 67:161-167
Background The orbitofrontal cortex (OFC) plays a crucial role in emotion-processing circuits and should therefore also be included in models of the pathophysiology of major depression. The aim of this study was to compare the functional connectivity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50cb259dbf72e19ca3972c3d91eb6193
https://doi.org/10.1016/j.biopsych.2009.08.022
https://doi.org/10.1016/j.biopsych.2009.08.022