Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Danuta Kunce"'
Autor:
Jan Izdebski, Ewa Gibula-Bruzda, Peter W. Schiller, Agnieszka Pachuta, Danuta Kunce, Nga N. Chung, Ewa Witkowska, Jolanta Kotlinska
Publikováno v:
Behavioural Pharmacology. 21:638-648
The aim of this study was to investigate whether the δ-opioid receptors are involved in the rewarding and reinstatement effect of cocaine in the conditioned place preference (CPP) test. Male Wistar rats were conditioned with cocaine (5 mg/kg) or sal
Publikováno v:
Synthesis. 2004:37-42
Two new guanidinylation reagents, N,N'-bis(ortho-chloro-Cbz)-S-methylisothiourea and N,N'-bis(ortho-bromo-Cbz)-S-methylisothiourea, were compared with the already known N,N'-bis(Boc)-S-methylisothiourea and N,N'-bis(Cbz)-S-methylisothiourea. The new
Publikováno v:
Letters in Peptide Science. 10:33-39
Publikováno v:
Letters in Peptide Science. 10:33-39
The application of p-nitrophenyl carbamate of Boc-ethylenediamine forthe solid-phase synthesis of peptidomimetics was examined. The per step yield of coupling was estimated using mass spectrometry, based on the repeated coupling of the same monomer i
Autor:
Jan Izdebski, Danuta Kunce
Publikováno v:
Journal of Peptide Science. 3:141-144
A competitive reaction of activated Boc-Ala-OH and Boc-Phe-OH with H-Leu-resin has been developed for assessing the relative efficiencies of different carbodiimides. This allowed a comparison of the efficiency of the carbodiimides N,N;′-dicyclohexy
Publikováno v:
ChemInform. 25
Autor:
Jan, Izdebski, Danuta, Kunce, Ewa, Witkowska, Ewa, Wolińska-Witort, Magdalena, Chmielowska, Bogusława, Baranowska
Publikováno v:
Neuro endocrinology letters. 28(4)
It has been found that hGH-RH analogues with increased resistance to enzymatic degradation have a much higher potency than the native hGH-RH (1-29)-NH2 and have an ability to partially reverse growth hormone deficiencies.The aim of these studies was
Autor:
Tomasz Gers, Monika Zelman, Monika Grabek, Nga N. Chung, Peter W. Schiller, Jan Izdebski, Danuta Kunce
Publikováno v:
Journal of peptide science : an official publication of the European Peptide Society. 13(1)
Two tris-alkoxycarbonyl homoarginine derivatives, Boc-Har{omega,omega'-[Z(2Br)]2}-OH and Boc-Har{omega,omega'-[Z(2Cl)]2}-OH, were prepared by guanidinylation of Boc-Lys-OH, and used for the synthesis of neo-endorphins and dynorphins. The results were
Publikováno v:
Journal of peptide science : an official publication of the European Peptide Society. 11(9)
The synthesis of p-nitrophenoxycarbonyl derivatives of 1-Boc-1,2-diaminoethane, 1-Boc-1,3-diaminopropane and 1-Boc-1,4-diaminobutane is described. These derivatives were used to synthesize five peptidomimetics, analogues of enkephalin, containing alk
Publikováno v:
Journal of peptide science : an official publication of the European Peptide Society. 11(1)
α-Alkoxycarbonyl protected ornithines were treated with N,N′-[Z(2Cl)]2-S-methylisothiourea and N,N′-[Z(2Br)]2-S-methylisothiourea, N,N′-Z2-S-methylisothiourea and N,N′-Boc2-S-methylisothiourea to form Nα, ω, ω′-tris-alkoxycarbonyl argin