Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Danuta Gutowska-Owsiak"'
Autor:
Adrian Kobiela, Weronika Hewelt-Belka, Joanna E. Frąckowiak, Natalia Kordulewska, Lilit Hovhannisyan, Aleksandra Bogucka, Rachel Etherington, Artur Piróg, Irena Dapic, Susanne Gabrielsson, Sara J. Brown, Graham S. Ogg, Danuta Gutowska-Owsiak
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionExosome-enriched small extracellular vesicles (sEVs) are nanosized organelles known to participate in long distance communication between cells, including in the skin. Atopic dermatitis (AD) is a chronic inflammatory skin disease for whic
Externí odkaz:
https://doaj.org/article/593e29e6575c497eac22c075c0ba127e
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Externí odkaz:
https://doaj.org/article/c8753e7aab2f48c28be79a737675287e
Autor:
Adrian Kobiela, Lilit Hovhannisyan, Paulina Jurkowska, Jorge Bernardino dela Serna, Aleksandra Bogucka, Milena Deptuła, Argho Aninda Paul, Kinga Panek, Ewa Czechowska, Michał Rychłowski, Aleksandra Królicka, Jacek Zieliński, Susanne Gabrielsson, Michał Pikuła, Magdalena Trzeciak, Graham S Ogg, Danuta Gutowska‐Owsiak
Publikováno v:
Journal of Extracellular Vesicles, Vol 12, Iss 6, Pp n/a-n/a (2023)
Abstract Filaggrin (FLG) protein is indispensable for multiple aspects of the epidermal barrier function but its accumulation in a monomeric filaggrin form may initiate premature keratinocytes death; it is unclear how filaggrin levels are controlled
Externí odkaz:
https://doaj.org/article/6bd1b44816ab49bbb6f551686c15c215
Autor:
Argho Aninda Paul, Natalia A. Szulc, Adrian Kobiela, Sara J. Brown, Wojciech Pokrzywa, Danuta Gutowska-Owsiak
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Background: Loss of function mutation in FLG is the major genetic risk factor for atopic dermatitis (AD) and other allergic manifestations. Presently, little is known about the cellular turnover and stability of profilaggrin, the protein encoded by F
Externí odkaz:
https://doaj.org/article/ae85490f1e744dfe9463f6a41ecd8718
Autor:
Ewa Izabela Podobas, Danuta Gutowska-Owsiak, Sébastien Moretti, Jarosław Poznański, Mariusz Kulińczak, Marcin Grynberg, Aleksandra Gruca, Arkadiusz Bonna, Dawid Płonka, Tomasz Frączyk, Graham Ogg, Wojciech Bal
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Externí odkaz:
https://doaj.org/article/88379c01f53e46378aa503f715e817c7
Autor:
Adrian Kobiela, Joanna E. Frackowiak, Anna Biernacka, Lilit Hovhannisyan, Aleksandra E. Bogucka, Kinga Panek, Argho Aninda Paul, Joanna Lukomska, Xinwen Wang, Eleni Giannoulatou, Aleksandra Krolicka, Jacek Zielinski, Milena Deptula, Michal Pikula, Susanne Gabrielsson, Graham S. Ogg, Danuta Gutowska-Owsiak
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Candida albicans (C. albicans) infection is a potential complication in the individuals with atopic dermatitis (AD) and can affect clinical course of the disease. Here, using primary keratinocytes we determined that atopic milieu promotes changes in
Externí odkaz:
https://doaj.org/article/d36aa09bc7a2411983ea2d29f0890996
Autor:
Ewa Izabela Podobas, Danuta Gutowska-Owsiak, Sébastien Moretti, Jarosław Poznański, Mariusz Kulińczak, Marcin Grynberg, Aleksandra Gruca, Arkadiusz Bonna, Dawid Płonka, Tomasz Frączyk, Graham Ogg, Wojciech Bal
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Deficiency in a principal epidermal barrier protein, filaggrin (FLG), is associated with multiple allergic manifestations, including atopic dermatitis and contact allergy to nickel. Toxicity caused by dermal and respiratory exposures of the general p
Externí odkaz:
https://doaj.org/article/feb5a556afd8461fa842804cbd90dfd6
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Extracellular vesicles (EVs), and especially exosomes, have been shown to mediate information exchange between distant cells; this process directly affects the biological characteristics and functionality of the recipient cell. As such, EVs significa
Externí odkaz:
https://doaj.org/article/464eed2367c54901bb226a98f45f2690
Autor:
Danuta Gutowska-Owsiak, Ewa I. Podobas, Christian Eggeling, Graham S. Ogg, Jorge Bernardino de la Serna
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Differentiation of keratinocytes is critical for epidermal stratification and formation of a protective stratum corneum. It involves a series of complex processes leading through gradual changes in characteristics and functions of keratinocytes up to
Externí odkaz:
https://doaj.org/article/ab229220a26242aab04c3d75474ceb9a
Autor:
Danuta Gutowska-Owsiak, Graham S. Ogg
Publikováno v:
npj Vaccines, Vol 2, Iss 1, Pp 1-10 (2017)
Abstract Allergic diseases are highly prevalent worldwide and affect all age groups, contributing to a high personal and socioeconomic burden. Treatment with an “allergy vaccine” or allergen immunotherapy aims to provide long-lasting benefits by
Externí odkaz:
https://doaj.org/article/94a5bc1adc39429493086bc6f92391b2