Sirtuin 2 inhibition modulates chromatin landscapes genome-wide to induce senescence in ATRX-deficient malignant glioma.

Autor: Malgulwar PB; Department of Translational Molecular Pathology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Danussi C; Sanofi, Research and Development, Cambridge, Massachusetts, USA., Dharmaiah S; Department of Translational Molecular Pathology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Johnson W; Department of Translational Molecular Pathology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Singh A; Department of Genomic Medicine, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Rai K; Department of Genomic Medicine, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Rao A; Departments of Biostatistics, Computational Medicine and Bioinformatics, and Radiation Oncology, University of Michigan, Ann Arbor, Michigan, USA., Huse JT; Department of Translational Molecular Pathology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.; Department of Pathology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.

Publikováno v: Neuro-oncology [Neuro Oncol] 2024 Jan 05; Vol. 26 (1), pp. 55-67.

ATRX loss in glioma results in dysregulation of cell-cycle phase transition and ATM inhibitor radio-sensitization.

Autor: Qin T; Department of Computational Medicine and Bioinformatics, University of Michigan Medical School, Ann Arbor, MI 48109, USA; Rogel Comprehensive Cancer Center, University of Michigan Medical School, Ann Arbor, MI 48109, USA., Mullan B; Department of Pediatrics, Division of Pediatric Hematology-Oncology, University of Michigan Medical School, 3520D MSRB 1, 1150 W Medical Center Drive, Ann Arbor, MI 48109, USA., Ravindran R; Department of Pediatrics, Division of Pediatric Hematology-Oncology, University of Michigan Medical School, 3520D MSRB 1, 1150 W Medical Center Drive, Ann Arbor, MI 48109, USA., Messinger D; Department of Pediatrics, Division of Pediatric Hematology-Oncology, University of Michigan Medical School, 3520D MSRB 1, 1150 W Medical Center Drive, Ann Arbor, MI 48109, USA., Siada R; Department of Pediatrics, Division of Pediatric Hematology-Oncology, University of Michigan Medical School, 3520D MSRB 1, 1150 W Medical Center Drive, Ann Arbor, MI 48109, USA., Cummings JR; Department of Pediatrics, Division of Pediatric Hematology-Oncology, University of Michigan Medical School, 3520D MSRB 1, 1150 W Medical Center Drive, Ann Arbor, MI 48109, USA., Harris M; Department of Pediatrics, Division of Pediatric Hematology-Oncology, University of Michigan Medical School, 3520D MSRB 1, 1150 W Medical Center Drive, Ann Arbor, MI 48109, USA., Muruganand A; Department of Pediatrics, Division of Pediatric Hematology-Oncology, University of Michigan Medical School, 3520D MSRB 1, 1150 W Medical Center Drive, Ann Arbor, MI 48109, USA., Pyaram K; Division of Biology, Kansas State University, Manhattan, KS 66506, USA., Miklja Z; Department of Pediatrics, Division of Pediatric Hematology-Oncology, University of Michigan Medical School, 3520D MSRB 1, 1150 W Medical Center Drive, Ann Arbor, MI 48109, USA., Reiber M; Department of Pediatrics, Division of Pediatric Hematology-Oncology, University of Michigan Medical School, 3520D MSRB 1, 1150 W Medical Center Drive, Ann Arbor, MI 48109, USA., Garcia T; Department of Pediatrics, Division of Pediatric Hematology-Oncology, University of Michigan Medical School, 3520D MSRB 1, 1150 W Medical Center Drive, Ann Arbor, MI 48109, USA., Tran D; Department of Pediatrics, Division of Pediatric Hematology-Oncology, University of Michigan Medical School, 3520D MSRB 1, 1150 W Medical Center Drive, Ann Arbor, MI 48109, USA., Danussi C; Department of Translational Molecular Pathology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA., Brosnan-Cashman J; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Pratt D; Department of Pathology, University of Michigan Medical School, Ann Arbor, MI 48109, USA., Zhao X; Department of Radiation Oncology, University of Michigan Medical School, Ann Arbor, MI 48109, USA., Rehemtulla A; Department of Radiation Oncology, University of Michigan Medical School, Ann Arbor, MI 48109, USA., Sartor MA; Department of Computational Medicine and Bioinformatics, University of Michigan Medical School, Ann Arbor, MI 48109, USA., Venneti S; Department of Pathology, University of Michigan Medical School, Ann Arbor, MI 48109, USA., Meeker AK; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Huse JT; Department of Translational Molecular Pathology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA., Morgan MA; Department of Radiation Oncology, University of Michigan Medical School, Ann Arbor, MI 48109, USA., Lowenstein PR; Departments of Neurosurgery and Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, MI 48109, USA., Castro MG; Departments of Neurosurgery and Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, MI 48109, USA., Yadav VN; Department of Pediatrics, Division of Pediatric Hematology-Oncology, University of Michigan Medical School, 3520D MSRB 1, 1150 W Medical Center Drive, Ann Arbor, MI 48109, USA., Koschmann C; Department of Pediatrics, Division of Pediatric Hematology-Oncology, University of Michigan Medical School, 3520D MSRB 1, 1150 W Medical Center Drive, Ann Arbor, MI 48109, USA. Electronic address: ckoschma@med.umich.edu.

Publikováno v: Cell reports [Cell Rep] 2022 Jan 11; Vol. 38 (2), pp. 110216.

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New insights into the structural role of EMILINs within the human skin microenvironment.

Autor: Schiavinato, Alvise^1,2,3 (AUTHOR), Marcous, Fady^1,2 (AUTHOR), Zuk, Alexandra V.² (AUTHOR), Keene, Douglas R.⁴ (AUTHOR), Tufa, Sara F.⁴ (AUTHOR), Mosquera, Laura M.^5,6,7 (AUTHOR), Zigrino, Paola⁸ (AUTHOR), Mauch, Cornelia⁸ (AUTHOR), Eckes, Beate⁹ (AUTHOR), Francois, Katrien¹⁰ (AUTHOR), De Backer, Julie^5,7,11 (AUTHOR), Hunzelmann, Nicolas⁸ (AUTHOR), Moinzadeh, Pia⁸ (AUTHOR), Krieg, Thomas^3,9,12 (AUTHOR), Callewaert, Bert^5,13 (AUTHOR), Sengle, Gerhard^1,2,3,14 (AUTHOR) gsengle@uni-koeln.de

Publikováno v: Scientific Reports. 12/5/2024, Vol. 14 Issue 1, p1-15. 15p.

METHOD FOR THE PREPARATION OF SPECIFIC ANTIBODIES AGAINST SACCHARIDIC ANTIGENS

Autor: UGGERI F., CAMPA C., COSLOVI A., COLOMBATTI A., DANUSSI C., PAOLETTI, SERGIO

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::074086f4794f4f8d2f525d467ae23769
http://hdl.handle.net/11368/1959003