Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Danthasinghe Waduge Badrajee Piyarathna"'
Autor:
Chandra Sekhar Amara, Karthik Reddy Kami Reddy, Yang Yuntao, Yuen San Chan, Danthasinghe Waduge Badrajee Piyarathna, Lacey Elizabeth Dobrolecki, David J. H. Shih, Zhongcheng Shi, Jun Xu, Shixia Huang, Matthew J. Ellis, Andrea B. Apolo, Leomar Y. Ballester, Jianjun Gao, Donna E. Hansel, Yair Lotan, H. Courtney Hodges, Seth P. Lerner, Chad J. Creighton, Arun Sreekumar, W. Jim Zheng, Pavlos Msaouel, Shyam M. Kavuri, Nagireddy Putluri
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract SMARCB1 loss has long been observed in many solid tumors. However, there is a need to elucidate targetable pathways driving growth and metastasis in SMARCB1-deficient tumors. Here, we demonstrate that SMARCB1 deficiency, defined as genomic S
Externí odkaz:
https://doaj.org/article/92dacc4a9b18472087b40b7343faadf4
Autor:
Anindita Ravindran, Kimiko L. Krieger, Akash K. Kaushik, Hélène Hovington, Sadia Mehdi, Danthasinghe Waduge Badrajee Piyarathna, Vasanta Putluri, Paul Basil, Uttam Rasaily, Franklin Gu, Truong Dang, Jong Min Choi, Rajni Sonavane, Sung Yun Jung, Lisha Wang, Rohit Mehra, Nancy L. Weigel, Nagireddy Putluri, David R. Rowley, Ganesh S. Palapattu, Chantal Guillemette, Louis Lacombe, Éric Lévesque, Arun Sreekumar
Publikováno v:
Cells, Vol 11, Iss 15, p 2329 (2022)
Prostate cancer (PCa) is the second most diagnosed cancer in the United States and is associated with metabolic reprogramming and significant disparities in clinical outcomes among African American (AA) men. While the cause is likely multi-factorial,
Externí odkaz:
https://doaj.org/article/21fa31e76e474fb6b719fbe7d3615cfd
Autor:
Karthik Reddy Kami Reddy, Danthasinghe Waduge Badrajee Piyarathna, Abu Hena Mostafa Kamal, Vasanta Putluri, Shiva Shankar Ravi, Roni J. Bollag, Martha K. Terris, Yair Lotan, Nagireddy Putluri
Publikováno v:
Metabolites, Vol 12, Iss 6, p 544 (2022)
Bladder Cancer (BLCA) is the ninth most frequently diagnosed cancer globally and the sixth most common cancer in the US. African Americans (AA) exhibit half the BLCA incidence compared to European Americans (EA), but they have a 70% higher risk of ca
Externí odkaz:
https://doaj.org/article/0c93db65d7db47a98c341ca9cc875da8
Autor:
Anindita Ravindran, Danthasinghe Waduge Badrajee Piyarathna, Jie Gohlke, Vasanta Putluri, Tanu Soni, Stacy Lloyd, Patricia Castro, Subramaniam Pennathur, Jeffrey A. Jones, Michael Ittmann, Nagireddy Putluri, George Michailidis, Thekkelnaycke M. Rajendiran, Arun Sreekumar
Publikováno v:
Metabolites, Vol 12, Iss 1, p 8 (2021)
African-American (AA) men are more than twice as likely to die of prostate cancer (PCa) than European American (EA) men. Previous in silico analysis revealed enrichment of altered lipid metabolic pathways in pan-cancer AA tumors. Here, we performed g
Externí odkaz:
https://doaj.org/article/d4b748a2eb2141c9a7c51357cc6c18e7
Autor:
Preeti Purwaha, Franklin Gu, Danthasinghe Waduge Badrajee Piyarathna, Theckelnaycke Rajendiran, Anindita Ravindran, Angela R. Omilian, Sao Jiralerspong, Gokul Das, Carl Morrison, Christine Ambrosone, Cristian Coarfa, Nagireddy Putluri, Arun Sreekumar
Publikováno v:
Metabolites, Vol 8, Iss 3, p 41 (2018)
The reprogramming of lipid metabolism is a hallmark of many cancers that has been shown to promote breast cancer progression. While several lipid signatures associated with breast cancer aggressiveness have been identified, a comprehensive lipidomic
Externí odkaz:
https://doaj.org/article/e28337a9714c471f8b98afc7bea72620
Autor:
Saroj Chakraborty, Anju Lulla, Xi Cheng, Ji-Youn Yeo, Juthika Mandal, Tao Yang, Xue Mei, Piu Saha, Rachel M. Golonka, Beng San Yeoh, Blair Mell, Wei Jia, Vasanta Putluri, Danthasinghe Waduge Badrajee Piyarathna, Nagireddy Putluri, Arun Sreekumar, Katie Meyer, Matam Vijay-Kumar, Bina Joe
Publikováno v:
Journal of Hypertension. 41:979-994
Autor:
Nagireddy Putluri, Cristian Coarfa, Arun Sreekumar, Yair Lotan, Andrew G. Sikora, MinJae Lee, Hugo Villanueva, Andrea B. Apolo, Seth P. Lerner, Roni J. Bollag, Martha K. Terris, Leomar Y. Ballester, Balasubramanyam Karanam, Friedrich-Carl von Rundstedt, Mariana Villanueva, Danthasinghe Waduge Badrajee Piyarathna, Matthew J. Robertson, Shiva Shankar Ravi, Vasanta Putluri, Chandra Sekhar Amara, Sri Ramya Donepudi, Dimuthu Perera, Chandrashekar R. Ambati, Jianrong Dong, Venkatrao Vantaku
Supplementary Table S8. Patient characteristics of bladder specimens used for figure 4B, 4C, and 4G.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecc721a6096be34bfb2eff9645a2c35e
https://doi.org/10.1158/1078-0432.22469423
https://doi.org/10.1158/1078-0432.22469423
Autor:
Nagireddy Putluri, Cristian Coarfa, Arun Sreekumar, Yair Lotan, Andrew G. Sikora, MinJae Lee, Hugo Villanueva, Andrea B. Apolo, Seth P. Lerner, Roni J. Bollag, Martha K. Terris, Leomar Y. Ballester, Balasubramanyam Karanam, Friedrich-Carl von Rundstedt, Mariana Villanueva, Danthasinghe Waduge Badrajee Piyarathna, Matthew J. Robertson, Shiva Shankar Ravi, Vasanta Putluri, Chandra Sekhar Amara, Sri Ramya Donepudi, Dimuthu Perera, Chandrashekar R. Ambati, Jianrong Dong, Venkatrao Vantaku
Supplementary Figure S6. Survival analysis of individual downregulated genes showed poor prognosis associated with CPT1B and PIGB in the Lindgren and Sjodahl cohorts; PLA2G4A in the Lindgren cohort; PIGV in the Kim and Sjodahl cohorts; ATP8B1 in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a6d63341d9f94f8fb08f06e17e94098
https://doi.org/10.1158/1078-0432.22469450.v1
https://doi.org/10.1158/1078-0432.22469450.v1
Autor:
Nagireddy Putluri, Cristian Coarfa, Arun Sreekumar, Yair Lotan, Andrew G. Sikora, MinJae Lee, Hugo Villanueva, Andrea B. Apolo, Seth P. Lerner, Roni J. Bollag, Martha K. Terris, Leomar Y. Ballester, Balasubramanyam Karanam, Friedrich-Carl von Rundstedt, Mariana Villanueva, Danthasinghe Waduge Badrajee Piyarathna, Matthew J. Robertson, Shiva Shankar Ravi, Vasanta Putluri, Chandra Sekhar Amara, Sri Ramya Donepudi, Dimuthu Perera, Chandrashekar R. Ambati, Jianrong Dong, Venkatrao Vantaku
Supplemental legend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::701cd47ec26357ac1929fd7c26689ef3
https://doi.org/10.1158/1078-0432.22469468
https://doi.org/10.1158/1078-0432.22469468
Autor:
Khoa Nguyen, Stanley Ly, Appalaraju Jaggupilli, Danthasinghe Waduge Badrajee Piyarathna, Henry C. Manning, Helen Piwnica-Worms, Bin Yuan, V. Lokesh Battula, Vivek Anand, Michael Andreeff, Fouad El-Dana, Zoe Arvanitis, Yuanqing Yan, Nagireddy Putluri
Publikováno v:
British Journal of Cancer. 126:615-627
BACKGROUND Metabolic stress resulting from nutrient deficiency is one of the hallmarks of a growing tumour. Here, we tested the hypothesis that metabolic stress induces breast cancer stem-like cell (BCSC) phenotype in triple-negative breast cancer (T