High-content multimodal analysis supports the IL-7/IL-7 receptor axis as a relevant therapeutic target in primary Sjögren's syndrome.

Autor: Desvaux E; LBAI, UMR1227, University of Brest, Inserm, Brest, France; Institut de Recherches Internationales Servier, Research and Development, Suresnes, France., Hemon P; LBAI, UMR1227, University of Brest, Inserm, Brest, France., Soret P; Institut de Recherches Internationales Servier, Research and Development, Suresnes, France., Le Dantec C; LBAI, UMR1227, University of Brest, Inserm, Brest, France., Chatzis L; LBAI, UMR1227, University of Brest, Inserm, Brest, France; Department of Pathophysiology, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece., Cornec D; LBAI, UMR1227, University of Brest, Inserm, Brest, France; CHU de Brest, Brest, France., Devauchelle-Pensec V; LBAI, UMR1227, University of Brest, Inserm, Brest, France; CHU de Brest, Brest, France., Elouej S; Institut de Recherches Internationales Servier, Research and Development, Suresnes, France., Duguet F; Institut de Recherches Internationales Servier, Research and Development, Suresnes, France., Laigle L; Institut de Recherches Internationales Servier, Research and Development, Suresnes, France., Poirier N; OSE Immunotherapeutics, Nantes, France., Moingeon P; Institut de Recherches Internationales Servier, Research and Development, Suresnes, France., Bretin S; Institut de Recherches Internationales Servier, Research and Development, Suresnes, France., Pers JO; LBAI, UMR1227, University of Brest, Inserm, Brest, France; CHU de Brest, Brest, France. Electronic address: pers@univ-brest.fr.

Publikováno v: Journal of autoimmunity [J Autoimmun] 2024 Dec; Vol. 149, pp. 103147. Date of Electronic Publication: 2023 Dec 18.

Stratification according to autoantibody status in systemic sclerosis reveals distinct molecular signatures.

Autor: Rouvière B; U1227, LBAI, Univ Brest, Inserm, and CHU Brest, Brest, France, Brest, France., Le Dantec C; U1227, LBAI, Univ Brest, Inserm, and CHU Brest, Brest, France, Brest, France., Bettacchioli E; U1227, LBAI, Univ Brest, Inserm, and CHU Brest, Brest, France, Brest, France., Beretta L; Referral Center for Systemic Autoimmune Diseases, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico di Milano, Milan, Italy., Foulquier N; U1227, LBAI, Univ Brest, Inserm, and CHU Brest, Brest, France, Brest, France., Cao C; U1227, LBAI, Univ Brest, Inserm, and CHU Brest, Brest, France, Brest, France., Jamin C; U1227, LBAI, Univ Brest, Inserm, and CHU Brest, Brest, France, Brest, France., Pers JO; U1227, LBAI, Univ Brest, Inserm, and CHU Brest, Brest, France, Brest, France., Kerick M; Instituto de Parasitologia y Biomedicina Lopez-Neyra, Granada, Granada, Spain., Martin J; Institute of Parasitology and Biomedicine López-Neyra, CSIC, Granada, Spain, Granada, Spain., Alarcón-Riquelme ME; Centre for Genomics and Oncological Research (GENYO), Pfizer-University of Granada-Andalusian Regional Government, Granada, Spain.; Institute for Environmental Medicine, Karolinska Institutet, Stockholm, Sweden., de Moreuil C; Médecine interne et pneumologie, CHU de Brest, Brest, France., Cornec D; U1227, LBAI, Univ Brest, Inserm, and CHU Brest, Brest, France, Brest, France., Hillion S; U1227, LBAI, Univ Brest, Inserm, and CHU Brest, Brest, France, Brest, France sophie.hillion@univ-brest.fr.

Publikováno v: Annals of the rheumatic diseases [Ann Rheum Dis] 2024 Oct 22. Date of Electronic Publication: 2024 Oct 22.

Épigénome et syndrome de Gougerot-Sjögren

Autor: Bordron, A., Charras, A., Le Dantec, C., Renaudineau, Y.

Publikováno v: In La Revue de médecine interne May 2018 39(5):346-351

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Deciphering the maturation of tertiary lymphoid structures in cancer and inflammatory diseases of the digestive tract using imaging mass cytometry.

Autor: Le Rochais M; Lymphocytes B, Autoimmunité et Immunothérapies (LBAI), Unité Mixte de Recherche (UMR)51227, Univ Brest, Inserm, Brest, France., Hémon P; Lymphocytes B, Autoimmunité et Immunothérapies (LBAI), Unité Mixte de Recherche (UMR)51227, Univ Brest, Inserm, Brest, France., Ben-Guigui D; Lymphocytes B, Autoimmunité et Immunothérapies (LBAI), Unité Mixte de Recherche (UMR)51227, Univ Brest, Inserm, Brest, France., Garaud S; Lymphocytes B, Autoimmunité et Immunothérapies (LBAI), Unité Mixte de Recherche (UMR)51227, Univ Brest, Inserm, Brest, France., Le Dantec C; Lymphocytes B, Autoimmunité et Immunothérapies (LBAI), Unité Mixte de Recherche (UMR)51227, Univ Brest, Inserm, Brest, France., Pers JO; Lymphocytes B, Autoimmunité et Immunothérapies (LBAI), Unité Mixte de Recherche (UMR)51227, Univ Brest, Inserm, Brest, France.; Centre Hospitalo-Universitaire (CHU) de Brest, Brest, France., Cornec D; Lymphocytes B, Autoimmunité et Immunothérapies (LBAI), Unité Mixte de Recherche (UMR)51227, Univ Brest, Inserm, Brest, France.; Centre Hospitalo-Universitaire (CHU) de Brest, Brest, France., Uguen A; Lymphocytes B, Autoimmunité et Immunothérapies (LBAI), Unité Mixte de Recherche (UMR)51227, Univ Brest, Inserm, Brest, France.; Centre Hospitalo-Universitaire (CHU) de Brest, Brest, France.

Publikováno v: Frontiers in immunology [Front Immunol] 2023 Apr 18; Vol. 14, pp. 1147480. Date of Electronic Publication: 2023 Apr 18 (Print Publication: 2023).