Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Dante W. Romanini"'
Publikováno v:
ACS Synthetic Biology. 1:602-609
Genetic recombination is central to the generation of molecular diversity and enhancement of evolutionary fitness in living systems. Methods such as DNA shuffling that recapitulate this diversity mechanism in vitro are powerful tools for engineering
Autor:
Kenneth N. Raymond, Ankona Datta, Dante W. Romanini, Praveena D. Garimella, Matthew B. Francis
Publikováno v:
Journal of the American Chemical Society. 133:14704-14709
MRI contrast agents providing very high relaxivity values can be obtained through the attachment of multiple gadolinium(III) complexes to the interior surfaces of genome-free viral capsids. In previous studies, the contrast enhancement was predicted
Engineering triterpene production in Saccharomyces cerevisiae-β-amyrin synthase from Artemisia annua
Publikováno v:
FEBS Journal. 275:1852-1859
Using a degenerate primer designed from triterpene synthase sequences, we have isolated a new gene from the medicinal plant Artemisia annua. The predicted protein is highly similar to beta-amyrin synthases (EC 5.4.99.-), sharing amino acid sequence i
Autor:
Dante W. Romanini, Matthew B. Francis
Publikováno v:
Bioconjugate Chemistry. 19:153-157
Recent efforts have yielded a number of short peptide sequences with useful binding, sensing, and cellular uptake properties. In order to attach these sequences to tyrosine residues on intact proteins, a three-component Mannich-type strategy is repor
Autor:
Dante W. Romanini, Virginia W. Cornish
Publikováno v:
Nature Chemistry. 4:248-250
Fluorescent labels can now be attached to a specific protein on the surface of live cells using a two-step method that reacts a norbornene — introduced using genetic encoding — with a variety of dyes.
Autor:
Allie C. Obermeyer, Jacob M. Hooker, Christopher R. Behrens, Matthew B. Francis, Dante W. Romanini, Elan M. Katz
A highly efficient protein bioconjugation method is described involving the addition of anilines to o-aminophenols in the presence of sodium periodate. The reaction takes place in aqueous buffer at pH 6.5 and can reach high levels of completion in 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b0b1c8f51b15c66b41b2bf2b0c6df63
https://europepmc.org/articles/PMC3389565/
https://europepmc.org/articles/PMC3389565/
Publikováno v:
Chemical communications (Cambridge, England). (10)
This Communication describes the chemo- and site-selective coupling of cell type-specific targeting peptides to a virus capsid containing aminophenylalanine residues.
Publikováno v:
Molecular imaging and biology. 10(4)
We have developed a modular synthetic strategy to append imaging agents to a viral capsid. The hollow protein shell of bacteriophage MS2 (mtMS2) was labeled on its inside surface with [18F]fluorobenzaldehyde through a multistep bioconjugation strateg
Autor:
Katherine E. Berry, Jacob M. Hooker, Dante W. Romanini, Ernest W Kovacs, Patrick G. Holder, Matthew B. Francis
Publikováno v:
Bioconjugate chemistry. 18(4)
With the development of covalent modification strategies for viral capsids comes the ability to convert them into modular carrier systems for drug molecules and imaging agents. With this overall goal in mind, we have used two orthogonal modification
Autor:
Dante W. Romanini, Amanda P. Crochet, Jacob M. Hooker, Jesse M. McFarland, John M. Antos, Amish A. Patel, Joshua M. Gilmore, S. David Tilley, Matthew B. Francis, Trung Van Nguyen, Neel Joshi
Publikováno v:
ChemInform. 37