Zobrazeno 1 - 10
of 209
pro vyhledávání: '"Dante, Rotili"'
Autor:
Gaia Di Timoteo, Andrea Giuliani, Adriano Setti, Martina C. Biagi, Michela Lisi, Tiziana Santini, Alessia Grandioso, Davide Mariani, Francesco Castagnetti, Eleonora Perego, Sabrina Zappone, Serena Lattante, Mario Sabatelli, Dante Rotili, Giuseppe Vicidomini, Irene Bozzoni
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease due to gradual motoneurons (MN) degeneration. Among the processes associated to ALS pathogenesis, there is the formation of cytoplasmic inclusions produced by agg
Externí odkaz:
https://doaj.org/article/fba55743618c4cde8526ef8ffa63acac
Autor:
Valeria Pecci, Fabiola Troisi, Aurora Aiello, Sara De Martino, Angela Carlino, Vincenzo Fiorentino, Cristian Ripoli, Dante Rotili, Francesco Pierconti, Maurizio Martini, Manuela Porru, Francesco Pinto, Antonello Mai, Pier Francesco Bassi, Claudio Grassi, Carlo Gaetano, Alfredo Pontecorvi, Lidia Strigari, Antonella Farsetti, Simona Nanni
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-17 (2024)
Abstract Background About 30% of Prostate cancer (PCa) patients progress to metastatic PCa that remains largely incurable. This evidence underlines the need for the development of innovative therapies. In this direction, the potential research focus
Externí odkaz:
https://doaj.org/article/2ef6b3a5976845e2bc6148989f39a138
Autor:
Bianca Cesaro, Alessia Iaiza, Fabio Piscopo, Marco Tarullo, Eleonora Cesari, Dante Rotili, Antonello Mai, Alberto Diana, Michela Londero, Luca Del Giacco, Riccardo Masetti, Alba Di Leone, Chiara Naro, Silvia Masciarelli, Giulia Fontemaggi, Claudio Sette, Francesco Fazi, Alessandro Fatica
Publikováno v:
Cancer Communications, Vol 44, Iss 2, Pp 282-286 (2024)
Externí odkaz:
https://doaj.org/article/baa518cfe6ab4474b91c71eab5250df6
Autor:
Valeria Pecci, Francesco Pierconti, Angela Carlino, Francesco Pinto, Ugo Gradilone, Sara De Martino, Dante Rotili, Claudio Grassi, Alfredo Pontecorvi, Carlo Gaetano, Lidia Strigari, Antonella Farsetti, Simona Nanni
Publikováno v:
Biomedicines, Vol 12, Iss 10, p 2322 (2024)
Introduction: Metastatic prostate cancer (PCa) presents a significant challenge in oncology due to its high mortality rate and the absence of effective biomarkers for predicting patient outcomes. Building on previous research that highlighted the cri
Externí odkaz:
https://doaj.org/article/564e92d63e6741fe9ff65b973f015738
Autor:
Alexandra Maure, Emeline Lawarée, Francesco Fiorentino, Alexandre Pawlik, Saideep Gona, Alexandre Giraud-Gatineau, Matthew J G Eldridge, Anne Danckaert, David Hardy, Wafa Frigui, Camille Keck, Claude Gutierrez, Olivier Neyrolles, Nathalie Aulner, Antonello Mai, Mélanie Hamon, Luis B Barreiro, Priscille Brodin, Roland Brosch, Dante Rotili, Ludovic Tailleux
Publikováno v:
PLoS Biology, Vol 22, Iss 4, p e3002259 (2024)
Antituberculosis drugs, mostly developed over 60 years ago, combined with a poorly effective vaccine, have failed to eradicate tuberculosis. More worryingly, multiresistant strains of Mycobacterium tuberculosis (MTB) are constantly emerging. Innovati
Externí odkaz:
https://doaj.org/article/e2eedf80218b48f79d34efc207ddd2fb
Autor:
Federico Appetecchia, Emanuele Fabbrizi, Francesco Fiorentino, Sara Consalvi, Mariangela Biava, Giovanna Poce, Dante Rotili
Publikováno v:
Pharmaceuticals, Vol 17, Iss 7, p 962 (2024)
Malaria drug research and development efforts have resurged in the last decade following the decelerating rate of mortality and malaria cases in endemic regions. The inefficiency of malaria interventions is largely driven by the spreading resistance
Externí odkaz:
https://doaj.org/article/330d05c967854380a29d9bd9da4a8c9e
Autor:
Flavia Trionfetti, Tonino Alonzi, Giulio Bontempi, Michela Terri, Cecilia Battistelli, Claudia Montaldo, Federica Repele, Dante Rotili, Sergio Valente, Clemens Zwergel, Giulia Matusali, Fabrizio Maggi, Delia Goletti, Marco Tripodi, Antonello Mai, Raffaele Strippoli
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
BackgroundDespite the significant progress achieved in understanding the pathology and clinical management of SARS-CoV-2 infection, still pathogenic and clinical issues need to be clarified. Treatment with modulators of epigenetic targets, i.e., epid
Externí odkaz:
https://doaj.org/article/31d5bba3c72849e2ab6a5faf175fe1bc
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1 (2023)
Carbonic anhydrases (CAs) are important regulators of pH homeostasis and participate in many physiological and pathological processes. CA activators (CAAs) are becoming increasingly important in the biomedical field since enhancing CA activity may ha
Externí odkaz:
https://doaj.org/article/865133b69dc742ddb26d3040cfd6651a
Autor:
Aide Negri, Marina Marozzi, Daniela Trisciuoglio, Dante Rotili, Antonello Mai, Federica Rizzi
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1 (2023)
Androgen deprivation therapy (ADT) is a common treatment for recurrent prostate cancer (PC). However, after a certain period of responsiveness, ADT resistance occurs virtually in all patients and the disease progresses to lethal metastatic castration
Externí odkaz:
https://doaj.org/article/23a51c8269fc43c7afe46977b921f61a
Autor:
Vanessa Marchant, Flavia Trionfetti, Lucia Tejedor-Santamaria, Sandra Rayego-Mateos, Dante Rotili, Giulio Bontempi, Alessandro Domenici, Paolo Menè, Antonello Mai, Catalina Martín-Cleary, Alberto Ortiz, Adrian M. Ramos, Raffaele Strippoli, Marta Ruiz-Ortega
Publikováno v:
Antioxidants, Vol 12, Iss 12, p 2055 (2023)
Peritoneal dialysis (PD) is a current replacement therapy for end-stage kidney diseases (ESKDs). However, long-term exposure to PD fluids may lead to damage of the peritoneal membrane (PM) through mechanisms involving the activation of the inflammato
Externí odkaz:
https://doaj.org/article/dae14fbc054248da8adab7eae6dcecf9