Impaired bone marrow B-cell development in mice with a bronchiolitis obliterans model of cGVHD

Autor: Kolupaev, Oleg V., Dant, Trisha A., Bommiasamy, Hemamalini, Bruce, Danny W., Fowler, Kenneth A., Tilley, Stephen L., McKinnon, Karen P., Sarantopoulos, Stefanie, Blazar, Bruce R., Coghill, James M., Serody, Jonathan S.

Publikováno v: In Blood Advances 25 September 2018 2(18):2307-2319

Type 2 Innate Lymphoid Cells Treat and Prevent GI Tract GvHD Through Enhanced Accumulation of Myeloid Derived Suppressor Cells

Autor: Bruce, Danny W, Stefanski, Heather E, Vincent, Benjamin G, Dant, Trisha A, Reisdorf, Shannon, Bommiasamy, Hemamalini, Serody, David A, Wilson, Justin E, McKinnon, Karen P, Shlomchik, Warren D, Blazar, Bruce R, Zaiss, Dietmar, McKenzie, Andrew N J, Coghill, James M, Serody, Jonathan S

Publikováno v: Bruce, D W, Stefanski, H E, Vincent, B G, Dant, T A, Reisdorf, S, Bommiasamy, H, Serody, D A, Wilson, J E, McKinnon, K P, Shlomchik, W D, Blazar, B R, Zaiss, D, McKenzie, A N J, Coghill, J M & Serody, J S 2017, ' Type 2 Innate Lymphoid Cells Treat and Prevent GI Tract GvHD Through Enhanced Accumulation of Myeloid Derived Suppressor Cells ', Journal of Clinical Investigation . https://doi.org/10.1172/JCI91816

Acute graft-versus-host disease (aGvHD) is the most common complication for patients undergoing allogeneic stem cell transplantation. Despite extremely aggressive therapy targeting donor T cells, patients with grade III or greater aGvHD of the lower

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3094::9cab17a19f0bb018a08c190b7e92c313
https://www.pure.ed.ac.uk/ws/files/31211743/Type_2_Innate_Lymphoid_Cells_Treat_and_Prevent_GI_Tract_GvHD_Through_Enhanced_Accumulation_of_Myeloid_Derived_Suppressor_Cells.pdf

T-cell expression of AhR inhibits the maintenance of pTreg cells in the gastrointestinal tract in acute GVHD.

Autor: Dant, Trisha A.¹, Kaifeng L. Lin², Bruce, Danny W.², Montgomery, Stephanie A.^2,3, Kolupaev, Oleg V.², Bommiasamy, Hemamalini², Bixby, Lisa M.², Woosley, John T.³, McKinnon, Karen P.^1,2, Gonzalez, Frank J.⁴, Blazar, Bruce R.⁵, Vincent, Benjamin G.^2,6,7, Coghill, James M.^2,8, Serody, Jonathan S.^1,2,8 jonathan_serody@med.unc.edu

Publikováno v: Blood. 7/20/2017, Vol. 130 Issue 3, p348-359. 12p.

Absence of Coronin 1B in Donor T Cells Diminishes Acute Gvhd By Impairing T Cell Accumulation in Secondary Lymphoid Tissue

Autor: Dant, Trisha ^*, Bruce, Danny ^*, Fulton, Leshara ^*, West, Michelle ^*, Foger, Niko ^*, Serody, Jonathan S.

Publikováno v: In Blood 3 December 2015 126(23):1880-1880