Výsledky vyhledávání - "Danny V. Chao"

Rac2 regulates immune complex–mediated granule polarization and exocytosis in neutrophils

Autor: Ramses Ilarraza, Danny V Chao, James A R Bodman, Alexandra Chesley, Adam Humble, Farzana Shaheen, Gary Eitzen, Paige Lacy

Publikováno v: Journal of Leukocyte Biology.

A key molecule for neutrophil degranulation is Rac2 guanosine triphosphatase. Neutrophils from Rac2 knockout mice (Rac2−/−) exhibit impaired primary granule exocytosis in response to cytochalasin B/f-Met-Leu-Phe, while secondary and tertiary gran

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::94f5eab3916d99b1fd103922e66af9f7
https://doi.org/10.1093/jleuko/qiad032

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Rac2 is involved in bleomycin-induced lung inflammation leading to pulmonary fibrosis

Autor: Juliana Rey-Parra, Narcy Arizmendi, Danny V Chao, Lakshmi Puttagunta, Bernard Thébaud, Kerri L Chung, Harissios Vliagoftis, Paige Lacy, Courtney Davidson

Publikováno v: Respiratory Research

Background Pulmonary fibrotic diseases induce significant morbidity and mortality, for which there are limited therapeutic options available. Rac2, a ras-related guanosine triphosphatase expressed mainly in hematopoietic cells, is a crucial molecule

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbaab7edec862c96e650b2dae9f9e49d
https://doi.org/10.1186/1465-9921-15-71

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Proteomic analysis of secretagogue-stimulated neutrophils implicates a role for actin and actin-interacting proteins in Rac2-mediated granule exocytosis

Autor: Troy Mitchell, Andrea N. Lo, Paige Lacy, Danny V Chao, Gary Eitzen, John D. Kim

Publikováno v: Proteome Science
Proteome Science, Vol 9, Iss 1, p 70 (2011)

Background Neutrophils are abundant leukocytes that play a primary role in defence against pathogens. Neutrophils enter sites of infection where they eliminate pathogens via phagocytosis and the release of antimicrobial mediators via degranulation. R

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::656d716b428e6152da0af4a1f3041c5b
https://doi.org/10.1186/1477-5956-9-70

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Akademický článek

Streptococcus pneumoniaeand Staphylococcus aureusPneumonia Induce Distinct Metabolic Responses.

Autor: Carolyn M. Slupsky, Andriy Cheypesh, Danny V. Chao, Hao Fu, Kathryn N. Rankin, Thomas J. Marrie, Paige Lacy

Publikováno v: Journal of Proteome Research; Jun2009, Vol. 8 Issue 6, p3029-3036, 8p

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