Zobrazeno 1 - 10
of 117
pro vyhledávání: '"Danny O'Hare"'
Autor:
Jennifer Lawrence, Danny O’Hare, Joseph van Batenburg-Sherwood, Mark Sutton, Alison Holmes, Timothy Miles Rawson
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract Beta-lactamase-producing Enterobacteriaceae present a significant therapeutic challenge. Current developments in phenotypic diagnostics focus primarily on rapid minimum inhibitory concentration (MIC) determination. There is a requirement for
Externí odkaz:
https://doaj.org/article/ea8ffc3f906b4d229bd97e9a5a05f04a
Publikováno v:
ACS Omega, Vol 9, Iss 27, Pp 29442-29452 (2024)
Externí odkaz:
https://doaj.org/article/a41778661431440daf0925a59c36c88b
Publikováno v:
Electrochemistry Communications, Vol 133, Iss , Pp 107147- (2021)
Cefiderocol is a novel siderophore-conjugated β-lactam antibiotic which has been approved for clinical use. It has demonstrated efficacy against infections caused by Gram-negative bacteria, including carbapenem-resistant strains. Novel antibiotics a
Externí odkaz:
https://doaj.org/article/732b886741e245ca932dac9273aaefc9
Autor:
Jin-young Kim, Danny O’Hare
Publikováno v:
Nano Convergence, Vol 5, Iss 1, Pp 1-7 (2018)
Abstract In this paper, a nano-porous polymer has been integrated into the microfluidics device as on-chip monolithic liquid chromatography column for separation of chemical and biological samples. Monolithic nano-porous polymer (MNP) was formed and
Externí odkaz:
https://doaj.org/article/54e00b914c92492aa6553e17cdb0c5c1
Autor:
Timothy M Rawson, PhD, Sally A N Gowers, PhD, David M E Freeman, PhD, Richard C Wilson, MPharm, Sanjiv Sharma, PhD, Mark Gilchrist, MPharm, Alasdair MacGowan, MD, Andrew Lovering, PhD, Mark Bayliss, PhD, Mathew Kyriakides, MSc, Pantelis Georgiou, PhD, Anthony E G Cass, ProfPhD, Danny O'Hare, PhD, Alison H Holmes, ProfMD
Publikováno v:
The Lancet: Digital Health, Vol 1, Iss 7, Pp e335-e343 (2019)
Summary: Background: Enhanced methods of drug monitoring are required to support the individualisation of antibiotic dosing. We report the first-in-human evaluation of real-time phenoxymethylpenicillin monitoring using a minimally invasive microneedl
Externí odkaz:
https://doaj.org/article/21e54a9aabf640d7b99ae3f0e4f9faa8
Publikováno v:
Biosensors, Vol 10, Iss 3, p 16 (2020)
Molecularly imprinted polymers (MIPs) can often bind target molecules with high selectivity and specificity. When used as MIPs, conductive polymers may have unique binding capabilities; they often contain aromatic rings and functional groups, which c
Externí odkaz:
https://doaj.org/article/6d50ba0b29564d7f87a77399edc1c670
Autor:
David M. E. Freeman, Damien K. Ming, Richard Wilson, Peter L. Herzog, Christopher Schulz, Alfons K. G. Felice, Yu-Chih Chen, Danny O’Hare, Alison H. Holmes, Anthony E. G. Cass
Publikováno v:
ACS Sensors. 8:1639-1647
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8522464998904f114c3244e71f41cc7d
https://doi.org/10.1021/acssensors.2c02780
https://doi.org/10.1021/acssensors.2c02780
Autor:
Damien K Ming, Saylee Jangam, Sally A N Gowers, Richard Wilson, David M E Freeman, Martyn G Boutelle, Anthony E G Cass, Danny O’Hare, Alison H Holmes
Publikováno v:
BMJ Innovations. 8:87-94
IntroductionDetermination of blood lactate levels supports decision-making in a range of medical conditions. Invasive blood-sampling and laboratory access are often required, and measurements provide a static profile at each instance. We conducted a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95b72d36f76e0b5457787ff38e8b9138
https://doi.org/10.1136/bmjinnov-2021-000864
https://doi.org/10.1136/bmjinnov-2021-000864
Autor:
Shulin Zhang, Yu-Chih Chen, Alaa Riezk, Damien Ming, Lidiia Tsvik, Leander Sützl, Alison Holmes, Danny O’Hare
Lactate concentration is of increasing interest as a diagnostic for sepsis, septic shock, and trauma. Compared with the traditional blood sample media, the exhaled breath condensate (EBC) has the advantages of non-invasiveness and higher user accepta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcea44ba55a54c8094efbc2fdb42e374
http://hdl.handle.net/10044/1/101542
http://hdl.handle.net/10044/1/101542
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 23; Pages: 15277
Angiogenesis, the growth of new blood vessels, is a critical factor of carcinogenesis. Neomycin and neamine, two drugs blocking the nuclear translocation of angiogenin (ANG), have been proven to inhibit tumour growth in vivo. However, the high toxici
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::347a08cc611e3fd2f3b6f080a1a941e6
https://pubmed.ncbi.nlm.nih.gov/36499606
https://pubmed.ncbi.nlm.nih.gov/36499606