Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Danny Mollerup Sørensen"'
Publikováno v:
PLoS ONE, Vol 17, Iss 10 (2022)
P5A ATPases are expressed in the endoplasmic reticulum (ER) of all eukaryotic cells, and their disruption results in pleiotropic phenotypes related to severe ER stress. They were recently proposed to function in peptide translocation although their s
Externí odkaz:
https://doaj.org/article/f00e73347c994566b4892fc8544858c4
Autor:
Danny Mollerup Sørensen, Tine Holemans, Sarah van Veen, Shaun Martin, Tugce Arslan, Ida Winther Haagendahl, Henrik Waldal Holen, Norin Nabil Hamouda, Jan Eggermont, Michael Palmgren, Peter Vangheluwe
Publikováno v:
PLoS ONE, Vol 13, Iss 3, p e0193228 (2018)
Several human P5-type transport ATPases are implicated in neurological disorders, but little is known about their physiological function and properties. Here, we investigated the relationship between the five mammalian P5 isoforms ATP13A1-5 in a comp
Externí odkaz:
https://doaj.org/article/555399a75b9c48a780e728b6ae0bb375
Autor:
Sara Rute Costa, Thomas Günther Pomorski, Helle Juel Martens, Daniele Silvestro, Danny Mollerup Sørensen, Henrik Waldal Holen, Jesper Torbøl Pedersen, Lyubomir Dimitrov Stanchev, Rosa L. López-Marqués, Michael G. Palmgren
Publikováno v:
Molecular Biology of the Cell
Sørensen, D M, Holen, H W, Pedersen, J T, Martens, H J, Silvestro, D, Stanchev, L D, Costa, S R, Pomorski, T G, López-Marqués, R L & Palmgren, M 2019, ' The P5A ATPase Spf1p is stimulated by phosphatidylinositol 4-phosphate and influences cellular sterol homeostasis ', Molecular Biology of the Cell, vol. 30, no. 9, pp. 1069-1084 . https://doi.org/10.1091/mbc.E18-06-0365
Sørensen, D M, Holen, H W, Pedersen, J T, Martens, H J, Silvestro, D, Stanchev, L D, Costa, S R, Pomorski, T G, López-Marqués, R L & Palmgren, M 2019, ' The P5A ATPase Spf1p is stimulated by phosphatidylinositol 4-phosphate and influences cellular sterol homeostasis ', Molecular Biology of the Cell, vol. 30, no. 9, pp. 1069-1084 . https://doi.org/10.1091/mbc.E18-06-0365
P5A ATPases are expressed in the endoplasmic reticulum (ER) of all eukaryotic cells, and their disruption results in severe ER stress. However, the function of these ubiquitous membrane proteins, which belong to the P-type ATPase superfamily, is unkn
Autor:
Paula Grenon, Michael G. Palmgren, Luciana R. Mazzitelli, Felicitas de Tezanos Pinto, Guido Daniel Petrovich, Hugo P. Adamo, Danny Mollerup Sørensen, Gerardo Raul Corradi
Publikováno v:
PLoS ONE, Vol 15, Iss 4, p e0232476 (2020)
Corradi, G R, Mazzitelli, L R, Petrovich, G D, Grenon, P, Sørensen, D M, Palmgren, M, De Tezanos Pinto, F & Adamo, H P 2020, ' Reduction of the P5A-ATPase Spf1p phosphoenzyme by a Ca 2+-dependent phosphatase ', PLoS ONE, vol. 15, no. 4, e0232476 . https://doi.org/10.1371/journal.pone.0232476
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
PLoS ONE
Corradi, G R, Mazzitelli, L R, Petrovich, G D, Grenon, P, Sørensen, D M, Palmgren, M, De Tezanos Pinto, F & Adamo, H P 2020, ' Reduction of the P5A-ATPase Spf1p phosphoenzyme by a Ca 2+-dependent phosphatase ', PLoS ONE, vol. 15, no. 4, e0232476 . https://doi.org/10.1371/journal.pone.0232476
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
PLoS ONE
P5 ATPases are eukaryotic pumps important for cellular metal ion, lipid and protein homeostasis; however, their transported substrate, if any, remains to be identified. Ca2+ was proposed to act as a ligand of P5 ATPases because it decreases the level
Autor:
Torbjörn Säll, Michael G. Palmgren, Björn M. Hallström, Danny Mollerup Sørensen, Karin Broberg
Publikováno v:
Physiologia Plantarum
Palmgren, M, Sørensen, D M, Hallstrom, B M, Säll, T & Broberg, K 2020, ' Evolution of P2A and P5A ATPases : ancient gene duplications and the red algal connection to green plants revisited ', Physiologia Plantarum, vol. 168, no. 3, pp. 630-647 . https://doi.org/10.1111/ppl.13008
Palmgren, M, Sørensen, D M, Hallstrom, B M, Säll, T & Broberg, K 2020, ' Evolution of P2A and P5A ATPases : ancient gene duplications and the red algal connection to green plants revisited ', Physiologia Plantarum, vol. 168, no. 3, pp. 630-647 . https://doi.org/10.1111/ppl.13008
In a search for slowly evolving nuclear genes that may cast light on the deep evolution of plants, we carried out phylogenetic analyses of two well-characterized subfamilies of P-type pumps (P2A and P5A ATPases) from representative branches of the eu
Autor:
Michael G. Palmgren, David L. Daleke, Kristina Faxén, Thomas Günther Pomorski, Gunnar Dittmar, Jürgen Schiller, Danny Mollerup Sørensen, Lisa Theorin, Rebekka Migotti, Rosa L. López-Marqués
Publikováno v:
Theorin, L, Faxén, K, Sørensen, D M, Migotti, R, Dittmar, G, Schiller, J, Daleke, D L, Palmgren, M, López-Marqués, R L & Pomorski, T G 2019, ' The lipid head group is the key element for substrate recognition by the P4 ATPase ALA2 : A phosphatidylserine flippase ', Biochemical Journal, vol. 476, no. 5, pp. 783-794 . https://doi.org/10.1042/BCJ20180891
Biochemical Journal
Biochemical Journal
Type IV P-type ATPases (P4 ATPases) are lipid flippases that catalyze phospholipid transport from the exoplasmic to the cytoplasmic leaflet of cellular membranes, but the mechanism by which they recognize and transport phospholipids through the lipid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09cb818aff1f870ec4f6b2bcedb4be38
https://curis.ku.dk/portal/da/publications/the-lipid-head-group-is-the-key-element-for-substrate-recognition-by-the-p4-atpase-ala2(961d07d8-bc76-4594-b802-c4a1537bb5b0).html
https://curis.ku.dk/portal/da/publications/the-lipid-head-group-is-the-key-element-for-substrate-recognition-by-the-p4-atpase-ala2(961d07d8-bc76-4594-b802-c4a1537bb5b0).html
Autor:
Michael G. Palmgren, Tine Holemans, Danny Mollerup Sørensen, Jan Eggermont, Norin Nabil Hamouda, Peter Vangheluwe, Ida Winther Haagendahl, Tugce Arslan, Sarah van Veen, Shaun Martin, Henrik Waldal Holen
Publikováno v:
PLoS ONE, Vol 13, Iss 3, p e0193228 (2018)
Sørensen, D M, Holemans, T, van Veen, S, Martin, S, Arslan, T, Haagendahl, I W, Holen, H W, Hamouda, N N, Eggermont, J, Palmgren, M B & Vangheluwe, P 2018, ' Parkinson disease related ATP13A2 evolved early in animal evolution ', PLOS ONE, vol. 13, no. 3, e0193228 . https://doi.org/10.1371/journal.pone.0193228
PLoS ONE
Sørensen, D M, Holemans, T, van Veen, S, Martin, S, Arslan, T, Haagendahl, I W, Holen, H W, Hamouda, N N, Eggermont, J, Palmgren, M B & Vangheluwe, P 2018, ' Parkinson disease related ATP13A2 evolved early in animal evolution ', PLOS ONE, vol. 13, no. 3, e0193228 . https://doi.org/10.1371/journal.pone.0193228
PLoS ONE
Several human P5-type transport ATPases are implicated in neurological disorders, but little is known about their physiological function and properties. Here, we investigated the relationship between the five mammalian P5 isoforms ATP13A1-5 in a comp
Autor:
Tine Holemans, Thorsten Pöppel, Matthis Synofzik, Christine Klein, Dae In Chang, Jean Samuel, Danny Mollerup Sørensen, Albena Jordanova, Dagmar Timmann, Bob Asselbergh, Shaun Martin, Ivailo Tournev, Jennifer Reichbauer, Teodora Chamova, Sarah van Veen, Ludger Schöls, Albena Andreeva, Alejandro Estrada-Cuzcano, Stephan Züchner, Rebecca Schüle, Peter Vangheluwe, Riet De Rycke
Publikováno v:
Brain 140(2), 287-305 (2017). doi:10.1093/brain/aww307
Brain
Brain
Hereditary spastic paraplegias are heterogeneous neurodegenerative disorders characterized by progressive spasticity of the lower limbs due to degeneration of the corticospinal motor neurons. In a Bulgarian family with three siblings affected by comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d4f6805d9040c3ac72308d892582147
https://pub.dzne.de/record/139142
https://pub.dzne.de/record/139142
Autor:
Teodora Chamova, S. van Veen, A Andreeva, Bob Asselbergh, Albena Jordanova, Peter Vangheluwe, D.I. Chang, Stephan Züchner, Shaun Martin, Tine Holemans, Alejandro Estrada-Cuzcano, Riet De Rycke, Ivailo Tournev, Danny Mollerup Sørensen, Jean Samuel
Publikováno v:
Journal of the Neurological Sciences. 381:379-380
Autor:
Michael G. Palmgren, Bjørn Panyella Pedersen, Poul Nissen, Kira Ekberg, Morten J. Buch-Pedersen, Ann K. Nielsen, Bjarke Veierskov, Danny Mollerup Sørensen
Publikováno v:
Ekberg, K, Pedersen, B P, Sørensen, D M, Nielsen, A K, Veierskov, B, Nissen, P, Palmgren, M G & Buch-Pedersen, M J 2010, ' Structural identification of cation binding pockets in the plasma membrane proton pump ', Proceedings of the National Academy of Sciences of the United States of America, vol. 107, no. 50, pp. 21400-5 . https://doi.org/10.1073/pnas.1010416107
The activity of P-type plasma membrane H + -ATPases is modulated by H + and cations, with K + and Ca 2+ being of physiological relevance. Using X-ray crystallography, we have located the binding site for Rb + as a K + congener, and for Tb 3+ and Ho 3