Chemically augmented malaria sporozoites display an altered immunogenic profile

Autor: Nikolas Duszenko, Roos van Schuijlenburg, Severine Chevalley-Maurel, Danny M. van Willigen, Laura de Bes-Roeleveld, Stefanie van der Wees, Chanel Naar, Els Baalbergen, Graham Heieis, Anton Bunschoten, Aldrik H. Velders, Blandine Franke-Fayard, Fijs W. B. van Leeuwen, Meta Roestenberg

Publikováno v: Frontiers in Immunology, Vol 14 (2023)

Despite promising results in malaria-naïve individuals, whole sporozoite (SPZ) vaccine efficacy in malaria-endemic settings has been suboptimal. Vaccine hypo-responsiveness due to previous malaria exposure has been posited as responsible, indicating

Externí odkaz: https://doaj.org/article/e88e831b639b4e63a2b6016ec6364f24

A Truncated 14-Amino-Acid Myelin Protein-Zero-Targeting Peptide for Fluorescence-Guided Nerve-Preserving Surgery

Autor: Nataliia Berehova, Maarten P. van Meerbeek, Samaneh Azargoshasb, Danny M. van Willigen, Leon J. Slof, Saaedeh Navaei Lavasani, Matthias N. van Oosterom, Fijs W. B. van Leeuwen, Tessa Buckle

Publikováno v: Biomolecules, Vol 13, Iss 6, p 942 (2023)

Background: The occurrence of accidental nerve damage during surgery and the increasing application of image guidance during head-and-neck surgery have highlighted the need for molecular targeted nerve-sparing interventions. The implementation of suc

Externí odkaz: https://doaj.org/article/57aa705097024078ab8df75932d4d9e3

Click Chemistry in the Design and Production of Hybrid Tracers

Autor: Albertus W. Hensbergen, Danny M. van Willigen, Mick M. Welling, Felicia A. van der Wijk, Clarize M. de Korne, Matthias N. van Oosterom, Margret Schottelius, Hans-Jürgen Wester, Tessa Buckle, Fijs W. B. van Leeuwen

Publikováno v: ACS Omega, Vol 4, Iss 7, Pp 12438-12448 (2019)

Externí odkaz: https://doaj.org/article/395ec4434a7e43a99b31f7fa94834f42

Advancing intraoperative magnetic tracing using 3D freehand magnetic particle imaging

Autor: Lennert Molenaar, Lejla Alic, Mick M. Welling, Melissa Mathilde van de Loosdrecht, Samaneh Azargoshasb, Danny M. van Willigen, Tessa Buckle, Fijs W. B. van Leeuwen, Alexander Winter, Matthias N. van Oosterom, Giuseppe Rosiello

Publikováno v: International Journal of Computer Assisted Radiology and Surgery
International journal of computer assisted radiology and surgery, 17(1), 211-218. Springer
International Journal of Computer Assisted Radiology and Surgery, 17(1), 211-218. SPRINGER HEIDELBERG

Purpose Sentinel lymph node biopsy is a routine procedure for nodal staging in penile cancer. Most commonly, this procedure is guided by radioactive tracers, providing various forms of preoperative and intraoperative guidance. This is further extende

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4de984c5d69ef094429b2883441c965e
http://europepmc.org/articles/PMC8738628

Hybrid Tracers Based on Cyanine Backbones Targeting Prostate-Specific Membrane Antigen: Tuning Pharmacokinetic Properties and Exploring Dye-Protein Interaction

Autor: Margret Schottelius, Henk G. van der Poel, Gabri van der Pluijm, Mick M. Welling, Albertus W. Hensbergen, Wytske M. van Weerden, Hans-Jürgen Wester, Fijs W. B. van Leeuwen, Felicia A. van der Wijk, Danny M. van Willigen, Tobias Maurer, Tessa Buckle

Publikováno v: Journal of Nuclear Medicine, 61(2), 234-241. Society of Nuclear Medicine and Molecular Imaging
Journal of Nuclear Medicine, 61(2), 234-241. SOC NUCLEAR MEDICINE INC

Prostate cancer surgery is currently being revolutionized by the use of prostate-specific membrane antigen (PSMA)-targeted radiotracers, for example, (99)mTc-labeled PSMA tracer analogs for radioguided surgery. The purpose of this study was to develo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8667a811e6c40e56d96ca47b09e5fa42
https://doi.org/10.2967/jnumed.119.233064