Zobrazeno 1 - 10
of 233
pro vyhledávání: '"Danny Ka Ho Wong"'
Autor:
Samuel Wan Ki Wong, Sze Keong Tey, Xiaowen Mao, Hiu Ling Fung, Zhi‐Jie Xiao, Danny Ka Ho Wong, Lung‐Yi Mak, Man‐Fung Yuen, Irene Oi‐Lin Ng, Jing Ping Yun, Yi Gao, Judy Wai Ping Yam
Publikováno v:
Advanced Science, Vol 10, Iss 26, Pp n/a-n/a (2023)
Abstract Hepatocellular carcinoma (HCC) is a hypervascular malignancy by which its growth and dissemination are largely driven by the modulation of tumor‐derived small extracellular vesicles (sEVs). Proteomic profiling of circulating sEVs of contro
Externí odkaz:
https://doaj.org/article/b2ced8f4b6de42bdb147c293f71797b1
Autor:
Zoe Leung, Frankie Chi Fat Ko, Sze Keong Tey, Ernest Man Lok Kwong, Xiaowen Mao, Bonnie Hei Man Liu, Angel Po Yee Ma, Yi Man Eva Fung, Chi-Ming Che, Danny Ka Ho Wong, Ching Lung Lai, Irene Oi-Lin Ng, Judy Wai Ping Yam
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-14 (2019)
Abstract Background Galectins are beta-galactose specific binding proteins. In human cancers, including hepatocellular carcinoma (HCC), galectin-1 (Gal-1) is often found to be overexpressed. In order to combat the dismal diagnosis and death rates of
Externí odkaz:
https://doaj.org/article/ca23d41184264966a82e84f0144b1621
Autor:
Xiaowen Mao, Sze Keong Tey, Cherlie Lot Sum Yeung, Ernest Man Lok Kwong, Yi Man Eva Fung, Clive Yik Sham Chung, Lung‐Yi Mak, Danny Ka Ho Wong, Man‐Fung Yuen, James Chung Man Ho, Herbert Pang, Maria Pik Wong, Carmen Oi‐Ning Leung, Terence Kin Wah Lee, Victor Ma, William Chi‐Shing Cho, Peihua Cao, Xiaoping Xu, Yi Gao, Judy Wai Ping Yam
Publikováno v:
Advanced Science, Vol 7, Iss 21, Pp n/a-n/a (2020)
Abstract In hepatocellular carcinoma (HCC) patients with extrahepatic metastasis, the lung is the most frequent site of metastasis. However, how the lung microenvironment favors disseminated cells remains unclear. Here, it is found that nidogen 1 (NI
Externí odkaz:
https://doaj.org/article/b579b31386644f0d93cd314e5ed657ce
Autor:
Jian-an Jia, Shuqin Zhang, Xin Bai, Meng Fang, Shipeng Chen, Xiaotao Liang, Shanfeng Zhu, Danny Ka-Ho Wong, Anye Zhang, Jianfeng Feng, Fengzhu Sun, Chunfang Gao
Publikováno v:
Virology Journal, Vol 19, Iss 1, Pp 1-15 (2022)
Abstract Background Chronic infection with hepatitis B virus (HBV) has been proved highly associated with the development of hepatocellular carcinoma (HCC). Aims The purpose of the study is to investigate the association between HBV preS region quasi
Externí odkaz:
https://doaj.org/article/9d54d0ba429c4b1cae95f31e943a24f4
Publikováno v:
Cell Death Discovery, Vol 7, Iss 1, Pp 1-11 (2021)
Abstract Hepatocellular carcinoma (HCC) is developed from uncontrolled cell growth after the malignant transformation of hepatocytes. The hepatitis B virus (HBV) X protein (HBx) has shown to induce cell cycle progression and hepatocarcinogenesis. A s
Externí odkaz:
https://doaj.org/article/a0112bc261ef463188d8544571a44555
Publikováno v:
BMC Gastroenterology, Vol 21, Iss 1, Pp 1-7 (2021)
Abstract Background Serum hepatitis B core-related antigen (HBcrAg) is a potential surrogate marker for intra-hepatic covalently-closed circular DNA in chronic hepatitis B (CHB). We aimed to study the profiles of serum HBcrAg in CHB patients treated
Externí odkaz:
https://doaj.org/article/114b856c107a46e892d4c107d2f88db4
Autor:
Saisai Zhang, Hein M. Tun, Dengwei Zhang, Hau-Tak Chau, Fung-Yu Huang, Hin Kwok, Danny Ka-Ho Wong, Lung-Yi Mak, Man-Fung Yuen, Wai-Kay Seto
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Non-alcoholic fatty liver disease (NAFLD), the world’s most common chronic liver disease, is increasingly linked to gut dysbiosis. Paneth cells secrete antimicrobial peptides that regulate the gut microbiome, but their role in the pathogenesis of N
Externí odkaz:
https://doaj.org/article/2b6cff05122e4e8c9895ed59ba538948
Autor:
Ching-Lung Lai, Danny Ka-Ho Wong, Gerald Tsz-Yau Wong, Wai-Kay Seto, James Fung, Man-Fung Yuen
Publikováno v:
JHEP Reports, Vol 2, Iss 3, Pp - (2020)
Background & Aims: Nucleos(t)ide analogues (NUCs) effectively suppress serum HBV DNA. Previously, we have identified 21 patients with undetectable covalently closed circular DNA (cccDNA) upon long-term NUC therapy. This study investigated the effect
Externí odkaz:
https://doaj.org/article/a82e1f74fff444ecad45099a21cb254b
Autor:
Man-Fung Yuen, Stephen Locarnini, Tien Huey Lim, Simone I. Strasser, William Sievert, Wendy Cheng, Alex J. Thompson, Bruce D. Given, Thomas Schluep, James Hamilton, Michael Biermer, Ronald Kalmeijer, Maria Beumont, Oliver Lenz, Filip De Ridder, Gavin Cloherty, Danny Ka-Ho Wong, Christian Schwabe, Kathy Jackson, Ching Lung Lai, Robert G. Gish, Edward Gane
Publikováno v:
Journal of Hepatology. 77:1287-1298
RNA interference therapy has been shown to reduce hepatitis B surface antigen (HBsAg) levels in preclinical models, which could confer functional cure in patients with chronic hepatitis B. This phase IIa trial (ClinicalTrials.gov Identifier: NCT03365
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::479448f9f509e9a64dd4d4daf760b90d
https://doi.org/10.1016/j.jhep.2022.07.010
https://doi.org/10.1016/j.jhep.2022.07.010
Autor:
Lung‐Yi Mak, Rex Wan‐Hin Hui, Chi‐Ho Lee, XianHua Mao, Ka‐Shing Cheung, Danny Ka‐Ho Wong, David Tak‐Wai Lui, James Fung, Man‐Fung Yuen, Wai‐Kay Seto
Publikováno v:
Hepatology. 77:606-618
Type 2 diabetes (T2D) is common among patients with chronic hepatitis B infection (CHB) and has been associated with increased risk of carcinogenesis, including HCC. We investigated factors associated with HCC and fibrosis progression among patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e2872c9ed659c6f1c314d98a0aaaa8d
https://doi.org/10.1002/hep.32716
https://doi.org/10.1002/hep.32716