Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Danny Kägebein"'
Autor:
Michael Delacher, Christian Schmidl, Yonatan Herzig, Minka Breloer, Wiebke Hartmann, Fabian Brunk, Danny Kägebein, Ulrike Träger, Ann-Cathrin Hofer, Sebastian Bittner, Dieter Weichenhan, Charles D. Imbusch, Agnes Hotz-Wagenblatt, Thomas Hielscher, Achim Breiling, Giuseppina Federico, Hermann-Josef Gröne, Roland M. Schmid, Michael Rehli, Jakub Abramson, Markus Feuerer
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-20 (2019)
Transcriptional regulator Rbpj is involved in T-helper subset differentiation. Here the authors show that expression of Rbpj in regulatory T cells is required to both regulate TH2 responses and regulate Treg TH2 differentiation potential.
Externí odkaz:
https://doaj.org/article/f8c425dfd10a45c698bf9c4a6526c87e
Autor:
Nadine Radomski, Danny Kägebein, Elisabeth Liebler-Tenorio, Axel Karger, Elke Rufer, Birke Andrea Tews, Stefanie Nagel, Rebekka Einenkel, Anne Müller, Annica Rebbig, Michael R. Knittler
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-18 (2017)
Abstract Chlamydiae are bacterial pathogens that grow in vacuolar inclusions. Dendritic cells (DCs) disintegrate these compartments, thereby eliminating the microbes, through auto/xenophagy, which also promotes chlamydial antigen presentation via MHC
Externí odkaz:
https://doaj.org/article/9c701232460348eeb4e19469f802be3d
Autor:
Minka Breloer, Jakub Abramson, Wiebke Hartmann, Agnes Hotz-Wagenblatt, Achim Breiling, Michael Delacher, Ulrike Träger, Danny Kägebein, Hermann Josef Gröne, Yonatan Herzig, Michael Rehli, Christian Schmidl, Dieter Weichenhan, Ann-Cathrin Hofer, Giuseppina Federico, Sebastian Bittner, Roland M. Schmid, Charles D. Imbusch, Fabian Brunk, Markus Feuerer, Thomas Hielscher
Publikováno v:
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-20 (2019)
Nature Communications, Vol 10, Iss 1, Pp 1-20 (2019)
The transcriptional regulator Rbpj is involved in T-helper (TH) subset polarization, but its function in Treg cells remains unclear. Here we show that Treg-specific Rbpj deletion leads to splenomegaly and lymphadenopathy despite increased numbers of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e535688a8e1892c29bcabaf26157c5ee
https://mediatum.ub.tum.de/doc/1544145/document.pdf
https://mediatum.ub.tum.de/doc/1544145/document.pdf
Publikováno v:
The Journal of Immunology. 195:5482-5494
The transporter associated with Ag processing (TAP) translocates proteasomally derived cytosolic peptides into the endoplasmic reticulum. TAP is a central component of the peptide-loading complex (PLC), to which tapasin (TPN) recruits MHC class I (MH
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41407183e93306cb092571160871099a
https://doi.org/10.4049/jimmunol.1500246
https://doi.org/10.4049/jimmunol.1500246
Autor:
Annica Rebbig, Birke Andrea Tews, Elke Rufer, Nadine Radomski, Danny Kägebein, Michael R. Knittler, Rebekka Einenkel, Stefanie Nagel, Elisabeth M. Liebler-Tenorio, Anne Müller, Axel Karger
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-18 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-18 (2017)
Chlamydiae are bacterial pathogens that grow in vacuolar inclusions. Dendritic cells (DCs) disintegrate these compartments, thereby eliminating the microbes, through auto/xenophagy, which also promotes chlamydial antigen presentation via MHC I. Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e1bddb9db37062af62551bd032440b0
https://pubmed.ncbi.nlm.nih.gov/28634388
https://pubmed.ncbi.nlm.nih.gov/28634388
Autor:
Danny Kägebein, Michael Delacher, Carl Herrmann, Charles D. Imbusch, Benedikt Brors, Philipp A. Lang, Achim Breiling, Katharina Bauer, Jan-Philipp Mallm, Ann Cathrin Hofer, Qi Wang, Agnes Hotz-Wagenblatt, Markus Feuerer, Felix Frauhammer, Ulrike Träger, Christoph Plass, Dieter Weichenhan
Publikováno v:
Nature Immunology
Regulatory T cells (Treg cells) perform two distinct functions: they maintain self-tolerance, and they support organ homeostasis by differentiating into specialized tissue Treg cells. We found that epigenetic modifications defined the molecular chara
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::728b1d02acf8f37804ba684d771c2d26
Autor:
Jürgen Rödel, Christina Große, Annette B. Vogel, Melanie Gutjahr, Danny Kägebein, Michael R. Knittler
Publikováno v:
Infection and Immunity. 82:993-1006
The obligate intracellular bacterial pathogen Chlamydia trachomatis is the causative agent of a variety of infectious diseases such as trachoma and sexually transmitted diseases. In infected target cells, C. trachomatis replicates within parasitophor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b3e0b5d006daa790029a9b15727da2f
https://doi.org/10.1128/iai.01473-13
https://doi.org/10.1128/iai.01473-13
Autor:
Mareen Sens, Michael R. Knittler, Tanja Weisser, Elisabeth M. Liebler-Tenorio, Melanie Gutjahr, Dorothee Fiegl, Danny Kägebein
Publikováno v:
The Journal of Immunology. 190:2791-2806
Dendritic cells (DCs) are among the first professional APCs encountered by the obligate intracellular bacterium Chlamydia during infection. Using an established mouse bone marrow–derived DC line, we show that DCs control chlamydial infection in mul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41adf64e82c5c2e7d4933a637c20d1df
https://doi.org/10.4049/jimmunol.1202741
https://doi.org/10.4049/jimmunol.1202741
Autor:
David M, Richards, Michael, Delacher, Yael, Goldfarb, Danny, Kägebein, Ann-Cathrin, Hofer, Jakub, Abramson, Markus, Feuerer
Publikováno v:
Progress in molecular biology and translational science. 136
Regulatory T cells (Tregs) are crucial mediators of self-tolerance in the periphery. They differentiate in the thymus, where interactions with thymus-resident antigen-presenting cells, an instructive cytokine milieu, and stimulation of the T cell rec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::28a48d11f6e7890f5e3a48676fdfec8d
https://pubmed.ncbi.nlm.nih.gov/26615097
https://pubmed.ncbi.nlm.nih.gov/26615097
Autor:
Ann Cathrin Hofer, Danny Kägebein, Michael Delacher, Jakub Abramson, Markus Feuerer, David M. Richards, Yael Goldfarb
Regulatory T cells (Tregs) are crucial mediators of self-tolerance in the periphery. They differentiate in the thymus, where interactions with thymus-resident antigen-presenting cells, an instructive cytokine milieu, and stimulation of the T cell rec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::64ccae2497af7ba581dd8d8efc4483bf
https://doi.org/10.1016/bs.pmbts.2015.07.014
https://doi.org/10.1016/bs.pmbts.2015.07.014