Zobrazeno 1 - 10
of 183
pro vyhledávání: '"Danny J. Schust"'
Autor:
Lyndsey E. Shorey-Kendrick, Victoria H. J. Roberts, Rahul J. D’Mello, Elinor L. Sullivan, Susan K. Murphy, Owen J. T. Mccarty, Danny J. Schust, Jason C. Hedges, A. J. Mitchell, Jose Juanito D. Terrobias, Charles A. Easley, Eliot R. Spindel, Jamie O. Lo
Publikováno v:
Clinical Epigenetics, Vol 15, Iss 1, Pp 1-15 (2023)
Abstract Background With the growing availability of cannabis and the popularization of additional routes of cannabis use beyond smoking, including edibles, the prevalence of cannabis use in pregnancy is rapidly increasing. However, the potential eff
Externí odkaz:
https://doaj.org/article/d2959dbd43f84fb09f1906fd4819661d
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Suppressyn (SUPYN) is the first host-cell encoded mammalian protein shown to inhibit cell–cell fusion. Its expression is restricted to the placenta, where it negatively regulates syncytia formation in villi. Since its chromosomal localizat
Externí odkaz:
https://doaj.org/article/a9e3892dd0a24e268738f0cb8e826ec9
Publikováno v:
Biomolecules, Vol 13, Iss 11, p 1627 (2023)
Cell fusion in the placenta is tightly regulated. Suppressyn is a human placental endogenous retroviral protein that inhibits the profusogenic activities of another well-described endogenous retroviral protein, syncytin-1. In this study, we aimed to
Externí odkaz:
https://doaj.org/article/52749514c2ed4ab3a39881f18e2a38c0
Autor:
Jie Zhou, Yuchen Tian, Ying Qu, Madyson Williams, Ye Yuan, Rowan M. Karvas, Megan A. Sheridan, Laura C. Schulz, Toshihiko Ezashi, Michael R. Roberts, Danny J. Schust
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
The placenta acts as a protective barrier to pathogens and other harmful substances present in the maternal circulation throughout pregnancy. Disruption of placental development can lead to complications of pregnancy such as preeclampsia, intrauterin
Externí odkaz:
https://doaj.org/article/ef4317e854f24c9fbdf2b85ad558ca16
Publikováno v:
Frontiers in Virology, Vol 2 (2022)
Throughout gestation, the placenta is vital for proper development of the fetus. Disruptions in trophoblast, the main functional cell type of the placenta, stress the pregnancy, with potential adverse outcomes for both mother and baby. While the plac
Externí odkaz:
https://doaj.org/article/5c49cd09b65049a5b8458d8c307d84a2
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Understanding the process of human placentation is important to the development of strategies for treatment of pregnancy complications. Several animal and in vitro human model systems for the general study human placentation have been used. The field
Externí odkaz:
https://doaj.org/article/9d56a4f98b22481399a9844fdeee3983
Autor:
Teka Khan, Arun S. Seetharam, Jie Zhou, Nathan J. Bivens, Danny J. Schust, Toshihiko Ezashi, Geetu Tuteja, R. Michael Roberts
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
One model to study the emergence of the human trophoblast (TB) has been the exposure of pluripotent stem cells to bone morphogenetic protein 4 (BMP4) in presence of inhibitors of ACTIVIN/TGFB; A83–01 and FGF2; PD173074 (BAP), which generates a mixt
Externí odkaz:
https://doaj.org/article/79713f32821b42e1869fd77e08ac5dc7
Autor:
Liping Li, Jie Zhou, Weijia Wang, Lina Huang, Jiaoqin Tu, Lyndsey Baiamonte, Moselle Stark, Mistie Mills, Thomas J. Hope, Erma Z. Drobnis, Alison J. Quayle, Danny J. Schust
Publikováno v:
Reproductive Biology and Endocrinology, Vol 17, Iss 1, Pp 1-11 (2019)
Abstract Background Hormonal contraceptives, particularly depot medroxyprogesterone acetate (DMPA), have been reported to be associated with substantially enhanced HIV acquisition; however, the biological mechanisms of this risk remain poorly underst
Externí odkaz:
https://doaj.org/article/229fe0adde404a08aed60cdf51ec9738
Autor:
Oluwafunmilayo Oyatogun, Mandeep Sandhu, Stephanie Barata-Kirby, Erin Tuller, Danny J. Schust
Publikováno v:
Therapeutic Advances in Reproductive Health, Vol 15 (2021)
The scenario in which a patient tests positive for human chorionic gonadotropin (hCG) in the absence of pregnancy can pose a diagnostic dilemma for clinicians. The term “phantom hCG” refers to persistently positive hCG levels on diagnostic testin
Externí odkaz:
https://doaj.org/article/8a2d2d6c725f46d68955e9344f65cdcb
Autor:
Lyndsey R Buckner, Erma Z Drobnis, Molly S Augustine, Lynette K Rogers, Jill Akers, Patricia D Mott, Thomas J Hope, Alison J Quayle, Danny J Schust
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0214152 (2019)
Progestin-only long-acting reversible contraceptives (LARCs) are increasingly popular among women seeking contraception; however, recent epidemiological studies suggest that systemically administered medroxyprogesterone acetate (MPA) may increase HIV
Externí odkaz:
https://doaj.org/article/dd0231c3e99b4eada9a9b78bd4aca0c7