Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Danny Boerrigter"'
Autor:
Tertia D. Purves-Tyson, Kate Robinson, Amelia M. Brown, Danny Boerrigter, Helen Q. Cai, Christin Weissleder, Samantha J. Owens, Debora A. Rothmond, Cynthia Shannon Weickert
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Increased cytokine and inflammatory-related transcripts are found in the ventral midbrain, a dopamine neuron-rich region associated with schizophrenia symptoms. In fact, half of schizophrenia cases can be defined as having a “high inflammatory/immu
Externí odkaz:
https://doaj.org/article/469da861d99b486b90ec11e5fa7102fc
Autor:
Danny Boerrigter, Thomas W. Weickert, Rhoshel Lenroot, Maryanne O’Donnell, Cherrie Galletly, Dennis Liu, Martin Burgess, Roxanne Cadiz, Isabella Jacomb, Vibeke S. Catts, Stu G. Fillman, Cynthia Shannon Weickert
Publikováno v:
Journal of Neuroinflammation, Vol 14, Iss 1, Pp 1-15 (2017)
Abstract Background Increases in pro-inflammatory cytokines are found in the brain and blood of people with schizophrenia. However, increased cytokines are not evident in all people with schizophrenia, but are found in a subset. The cytokine changes
Externí odkaz:
https://doaj.org/article/ddfc27af82f04be5b915e534eef11185
Autor:
David Lloyd, Maryanne O'Donnell, Andrew R. Lloyd, Cynthia Shannon Weickert, Helen Q Cai, Jason M. Bruggemann, Ellen Ji, Cherrie Gallety, Dennis Liu, Danny Boerrigter, Thomas W. Weickert, Rhoshel K. Lenroot
Publikováno v:
Brain, behavior, and immunity. 101
Background There is growing evidence for complement system involvement in the pathophysiology of schizophrenia, although the extent and magnitude of complement factor disturbances has not been fully reported. It also remains unclear whether complemen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99b35770543ff976d21cf1762caa68d8
https://pubmed.ncbi.nlm.nih.gov/34808287
https://pubmed.ncbi.nlm.nih.gov/34808287
Autor:
Cynthia Shannon Weickert, Ryan P. Balzan, Maryanne O'Donnell, Gilles J. Guillemin, Jochen Kindler, Rhoshel K. Lenroot, Thomas W. Weickert, Chai K. Lim, Cherrie Galletly, Danny Boerrigter, Jason M. Bruggemann, Dennis Liu, Kelly R. Jacobs
Publikováno v:
Molecular Psychiatry
Kindler, Jochen; Lim, Chai K.; Weickert, Cynthia Shannon; Boerrigter, Danny; Galletly, Cherrie; Liu, Dennis; Jacobs, Kelly R.; Balzan, Ryan; Bruggemann, Jason; O’Donnell, Maryanne; Lenroot, Rhoshel; Guillemin, Gilles J.; Weickert, Thomas W. (2020). Dysregulation of kynurenine metabolism is related to proinflammatory cytokines, attention, and prefrontal cortex volume in schizophrenia. Molecular psychiatry, 25(11), pp. 2860-2872. Springer Nature 10.1038/s41380-019-0401-9
Kindler, Jochen; Lim, Chai K.; Weickert, Cynthia Shannon; Boerrigter, Danny; Galletly, Cherrie; Liu, Dennis; Jacobs, Kelly R.; Balzan, Ryan; Bruggemann, Jason; O’Donnell, Maryanne; Lenroot, Rhoshel; Guillemin, Gilles J.; Weickert, Thomas W. (2020). Dysregulation of kynurenine metabolism is related to proinflammatory cytokines, attention, and prefrontal cortex volume in schizophrenia. Molecular psychiatry, 25(11), pp. 2860-2872. Springer Nature 10.1038/s41380-019-0401-9
The kynurenine pathway (KP) of tryptophan (TRP) catabolism links immune system activation with neurotransmitter signaling. The KP metabolite kynurenic acid (KYNA) is increased in the brains of people with schizophrenia. We tested the extent to which:
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::763cfb1b34c85ad4022bd4108d017714
https://doi.org/10.1038/s41380-019-0401-9
https://doi.org/10.1038/s41380-019-0401-9
Autor:
Amelia M. Brown, Illya Conn, Danny Boerrigter, Cynthia Shannon Weickert, Tertia D. Purves-Tyson
Publikováno v:
Journal of Neuroimmunology. 364:577813
Maternal immune activation (MIA) with poly(I:C) is a preclinical paradigm for schizophrenia and autism research. Methodological variations, including poly(I:C) molecular weight, contribute to inconsistencies in behavioural and molecular outcomes. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ba50b93797be6135b153a11a73eb859
https://doi.org/10.1016/j.jneuroim.2022.577813
https://doi.org/10.1016/j.jneuroim.2022.577813
Autor:
Suheyla Cetin-Karayumak, Ofer Pasternak, Hayley F. North, Vanessa Cropley, Paul A. Tooney, Andrew Zalesky, Danny Boerrigter, Yogesh Rathi, Jinglei Lv, Maria A Di Biase, Christos Pantelis, Cynthia Shannon Weickert
Publikováno v:
Schizophr Bull
Introduction Clarifying the role of neuroinflammation in schizophrenia is subject to its detection in the living brain. Free-water (FW) imaging is an in vivo diffusion-weighted magnetic resonance imaging (dMRI) technique that measures water molecules
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0e0b9eae209b9aae292502efe1be102
https://pubmed.ncbi.nlm.nih.gov/33085749
https://pubmed.ncbi.nlm.nih.gov/33085749
Autor:
Danny Boerrigter, Cynthia Shannon Weickert, Kathryn J. Mathews, Helen J. Ball, Kay L. Double, Katherine M. Allen
Publikováno v:
Aging Cell
Summary Reduced neurogenesis in the aging mammalian hippocampus has been linked to cognitive deficits and increased risk of dementia. We utilized postmortem human hippocampal tissue from 26 subjects aged 18–88 years to investigate changes in expres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55b7dafa1f8ec90e5c788a8e4f7aa7af
https://doi.org/10.1111/acel.12641
https://doi.org/10.1111/acel.12641
Autor:
Debora A. Rothmond, Danny Boerrigter, Tertia D. Purves-Tyson, Helen Q Cai, Cynthia Shannon Weickert
Publikováno v:
Schizophrenia Bulletin
Background Neuroinflammation and dopamine dysregulation contribute to psychosis and cognitive deficits in schizophrenia. Approximately 50% of people with schizophrenia have elevated gene expression of proinflammatory cytokines in the postmortem midbr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dd8533405147fbc9d9ece39c934a091
http://europepmc.org/articles/PMC7234088
http://europepmc.org/articles/PMC7234088
Autor:
Stu G. Fillman, Isabella Jacomb, Cherrie Galletly, Cynthia Shannon Weickert, Rhoshel K. Lenroot, Dennis Liu, Vibeke S. Catts, Thomas W. Weickert, Martin Burgess, Roxanne Cadiz, Danny Boerrigter, Maryanne O'Donnell
Publikováno v:
Journal of Neuroinflammation
Journal of Neuroinflammation, Vol 14, Iss 1, Pp 1-15 (2017)
Journal of Neuroinflammation, Vol 14, Iss 1, Pp 1-15 (2017)
Background Increases in pro-inflammatory cytokines are found in the brain and blood of people with schizophrenia. However, increased cytokines are not evident in all people with schizophrenia, but are found in a subset. The cytokine changes that best
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc45763504e1e60df43478e6fbd0018b
https://doi.org/10.1186/s12974-017-0962-y
https://doi.org/10.1186/s12974-017-0962-y
Autor:
Thomas W. Weickert, Maryanne O'Donnell, Isabella Jacomb, Vibeke S. Catts, Danny Boerrigter, Cyndi Shannon Weickert, Dennis Liu, Rhoshel K. Lenroot, Martin Burgess, Cherrie Galletly, Roxanne Cadiz
Background: Cytokine messenger RNA (mRNA) transcripts derived from peripheral blood can be used to identify individuals with putative inflammation, and patients with schizophrenia increased proportions of those with elevated cytokines. However, the r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea5ff0c6d412de03dbe621c34d89778d
https://europepmc.org/articles/PMC5475896/
https://europepmc.org/articles/PMC5475896/
