Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Danny, Orabi"'
Autor:
Robert N Helsley, Tatsunori Miyata, Anagha Kadam, Venkateshwari Varadharajan, Naseer Sangwan, Emily C Huang, Rakhee Banerjee, Amanda L Brown, Kevin K Fung, William J Massey, Chase Neumann, Danny Orabi, Lucas J Osborn, Rebecca C Schugar, Megan R McMullen, Annette Bellar, Kyle L Poulsen, Adam Kim, Vai Pathak, Marko Mrdjen, James T Anderson, Belinda Willard, Craig J McClain, Mack Mitchell, Arthur J McCullough, Svetlana Radaeva, Bruce Barton, Gyongyi Szabo, Srinivasan Dasarathy, Jose Carlos Garcia-Garcia, Daniel M Rotroff, Daniela S Allende, Zeneng Wang, Stanley L Hazen, Laura E Nagy, Jonathan Mark Brown
Publikováno v:
eLife, Vol 11 (2022)
There is mounting evidence that microbes residing in the human intestine contribute to diverse alcohol-associated liver diseases (ALD) including the most deadly form known as alcohol-associated hepatitis (AH). However, mechanisms by which gut microbe
Externí odkaz:
https://doaj.org/article/9d2e1ecd214249d6a556320886d84ab0
Autor:
Rebecca C Schugar, Christy M Gliniak, Lucas J Osborn, William Massey, Naseer Sangwan, Anthony Horak, Rakhee Banerjee, Danny Orabi, Robert N Helsley, Amanda L Brown, Amy Burrows, Chelsea Finney, Kevin K Fung, Frederick M Allen, Daniel Ferguson, Anthony D Gromovsky, Chase Neumann, Kendall Cook, Amy McMillan, Jennifer A Buffa, James T Anderson, Margarete Mehrabian, Maryam Goudarzi, Belinda Willard, Tytus D Mak, Andrew R Armstrong, Garth Swanson, Ali Keshavarzian, Jose Carlos Garcia-Garcia, Zeneng Wang, Aldons J Lusis, Stanley L Hazen, Jonathan Mark Brown
Publikováno v:
eLife, Vol 11 (2022)
Obesity has repeatedly been linked to reorganization of the gut microbiome, yet to this point obesity therapeutics have been targeted exclusively toward the human host. Here, we show that gut microbe-targeted inhibition of the trimethylamine N-oxide
Externí odkaz:
https://doaj.org/article/1bf775b855894d52aa435ffcd48a01d8
Autor:
Danny Orabi, Lucas J. Osborn, Kevin Fung, William Massey, Anthony J. Horak III, Federico Aucejo, Ibrahim Choucair, Beckey DeLucia, Zeneng Wang, Jan Claesen, J. Mark Brown
Publikováno v:
JCI Insight, Vol 6, Iss 9 (2021)
Gut microbe–derived metabolites influence human physiology and disease. However, establishing mechanistic links between gut microbial metabolites and disease pathogenesis in animal models remains challenging. The major route of absorption for micro
Externí odkaz:
https://doaj.org/article/20d01f26005448d79fdbf2c18d5b6afd
Autor:
William Massey, Lucas J. Osborn, Rakhee Banerjee, Anthony Horak, Kevin K. Fung, Danny Orabi, E. Ricky Chan, Naseer Sangwan, Zeneng Wang, J. Mark Brown
Publikováno v:
Metabolites, Vol 12, Iss 4, p 364 (2022)
Exposure to some environmental pollutants can have potent endocrine-disrupting effects, thereby promoting hormone imbalance and cardiometabolic diseases such as non-alcoholic fatty liver disease (NAFLD), diabetes, and cardiorenal diseases. Recent evi
Externí odkaz:
https://doaj.org/article/271c68498b3a477498a649a2d9e4c506
Autor:
Robert N Helsley, Venkateshwari Varadharajan, Amanda L Brown, Anthony D Gromovsky, Rebecca C Schugar, Iyappan Ramachandiran, Kevin Fung, Mohammad Nasser Kabbany, Rakhee Banerjee, Chase K Neumann, Chelsea Finney, Preeti Pathak, Danny Orabi, Lucas J Osborn, William Massey, Renliang Zhang, Anagha Kadam, Brian E Sansbury, Calvin Pan, Jessica Sacks, Richard G Lee, Rosanne M Crooke, Mark J Graham, Madeleine E Lemieux, Valentin Gogonea, John P Kirwan, Daniela S Allende, Mete Civelek, Paul L Fox, Lawrence L Rudel, Aldons J Lusis, Matthew Spite, J Mark Brown
Publikováno v:
eLife, Vol 8 (2019)
Recent studies have identified a genetic variant rs641738 near two genes encoding membrane bound O-acyltransferase domain-containing 7 (MBOAT7) and transmembrane channel-like 4 (TMC4) that associate with increased risk of non-alcoholic fatty liver di
Externí odkaz:
https://doaj.org/article/f9448bea0b9e426ea0147da3a9110b3e
Autor:
Lucas J. Osborn, Karlee Schultz, William Massey, Beckey DeLucia, Ibrahim Choucair, Venkateshwari Varadharajan, Rakhee Banerjee, Kevin Fung, Anthony J. Horak, Danny Orabi, Ina Nemet, Laura E. Nagy, Zeneng Wang, Daniela S. Allende, Belinda B. Willard, Naseer Sangwan, Adeline M. Hajjar, Christine McDonald, Philip P. Ahern, Stanley L. Hazen, J. Mark Brown, Jan Claesen
Publikováno v:
Proceedings of the National Academy of Sciences. 119
The molecular mechanisms by which dietary fruits and vegetables confer cardiometabolic benefits remain poorly understood. Historically, these beneficial properties have been attributed to the antioxidant activity of flavonoids. Here, we reveal that t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c73723f5bb064133482573cdd7f3a560
https://doi.org/10.1073/pnas.2202934119
https://doi.org/10.1073/pnas.2202934119
Autor:
Cristiano Quintini, Choon-Hyuck D Kwon, Amika Moro, Federico Aucejo, Danny Orabi, Eren Berber, John O Barron, Kazunari Sasaki
Publikováno v:
Surgical Endoscopy. 36:3601-3609
Laparoscopic liver resection (LLR) involves a difficult learning curve, for which multiple difficulty scores have been proposed to assist with safe adaptation. The IWATE Criteria is a 4-level difficulty score shown to correlate with conversion to ope
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::08a95d2be89d3141beb040b57be6ad16
https://doi.org/10.1007/s00464-021-08561-4
https://doi.org/10.1007/s00464-021-08561-4
Autor:
Anagha Kadam, Tatsunori Miyata, Robert N Helsley, Venkateshwari Varadharajan, Naseer Sangwan, Emily C Huang, Rakhee Banerjee, Amanda L Brown, Kevin K Fung, William J Massey, Chase Neumann, Danny Orabi, Lucas J Osborn, Rebecca C Schugar, Megan R McMullen, Annette Bellar, Kyle L Poulsen, Adam Kim, Vai Pathak, Marko Mrdjen, James T Anderson, Belinda Willard, Craig J McClain, Mack Mitchell, Arthur J McCullough, Svetlana Radaeva, Bruce Barton, Gyongyi Szabo, Srinivasan Dasarathy, Jose Carlos Garcia-Garcia, Daniel M Rotroff, Daniela S Allende, Zeneng Wang, Stanley L Hazen, Laura E Nagy, Jonathan Mark Brown
Publikováno v:
eLife, Vol 11 (2022)
BACKGROUNDThere is mounting evidence that microbes resident in the human intestine contribute to diverse alcohol-associated liver diseases (ALD) including the most deadly form known as alcohol-associated hepatitis (AH). However, mechanisms by which g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a456403e6a515faef7af837fdf0eddaa
https://elifesciences.org/articles/76554
https://elifesciences.org/articles/76554
Autor:
Anagha Kadam, Tatsunori Miyata, Robert N Helsley, Venkateshwari Varadharajan, Naseer Sangwan, Emily C Huang, Rakhee Banerjee, Amanda L Brown, Kevin K Fung, William J Massey, Chase Neumann, Danny Orabi, Lucas J Osborn, Rebecca C Schugar, Megan R McMullen, Annette Bellar, Kyle L Poulsen, Adam Kim, Vai Pathak, Marko Mrdjen, James T Anderson, Belinda Willard, Craig J McClain, Mack Mitchell, Arthur J McCullough, Svetlana Radaeva, Bruce Barton, Gyongyi Szabo, Srinivasan Dasarathy, Jose Carlos Garcia-Garcia, Daniel M Rotroff, Daniela S Allende, Zeneng Wang, Stanley L Hazen, Laura E Nagy, Jonathan Mark Brown
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e111d82df6b3cf88234ff1e48dd8e3bd
https://doi.org/10.7554/elife.76554.sa2
https://doi.org/10.7554/elife.76554.sa2
Autor:
Lucas J Osborn, Christy M Gliniak, Rebecca C Schugar, William Massey, Naseer Sangwan, Anthony Horak, Rakhee Banerjee, Danny Orabi, Robert N Helsley, Amanda L Brown, Amy Burrows, Chelsea Finney, Kevin K Fung, Frederick M Allen, Daniel Ferguson, Anthony D Gromovsky, Chase Neumann, Kendall Cook, Amy McMillan, Jennifer A Buffa, James T Anderson, Margarete Mehrabian, Maryam Goudarzi, Belinda Willard, Tytus D Mak, Andrew R Armstrong, Garth Swanson, Ali Keshavarzian, Jose Carlos Garcia-Garcia, Zeneng Wang, Aldons J Lusis, Stanley L Hazen, Jonathan Mark Brown
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d246a0d278b007c8b123082431babca
https://doi.org/10.7554/elife.63998.sa2
https://doi.org/10.7554/elife.63998.sa2