Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Dannielle Upton"'
Autor:
Elisha Hayden, Laura Franshaw, Dannielle Upton, Jie Liu, Hieu Nguyen, Swapna Joshi, Maria Tsoli, Emmy Dolman, Benjamin Rayner, David Ziegler
Publikováno v:
Cancer Research. 83:1561-1561
Diffuse Midline Gliomas (DMGs) are devastating and incurable pediatric brain tumours. DMGs are characterised by epigenetic aberrations in the form of histone modifications, coupled with mitotic abnormalities, which together drive a stem-like transcri
Autor:
Dannielle Upton, Sandra George, Jie Liu, Dongpo Doug Cai, Steven Yung-Chang Su, Benjamin Rayner, Maria Tsoli, David Ziegler
Publikováno v:
Neuro-Oncology. 24:i19-i19
Diffuse Intrinsic Pontine Gliomas (DIPG) are a subset of Diffuse Midline Gliomas (DMG) and are the most devastating of all brain tumours. There are currently no effective treatments. ACT001 is a novel anti-cancer agent in clinical development that is
Autor:
Chelsea Mayoh, Mark R. Burns, Ruby Pandher, Anahid Ehteda, Michelle Haber, Laura D. Gamble, David S. Ziegler, Caitlin Ung, Dannielle Upton, Nada Jabado, Claudia L. Kleinman, Maria Tsoli, Steven Hébert, Denise M. T. Yu, Murray D. Norris, Aaminah Khan
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Diffuse intrinsic pontine glioma (DIPG) is an incurable malignant childhood brain tumor, with no active systemic therapies and a 5-year survival of less than 1%. Polyamines are small organic polycations that are essential for DNA replication, transla
Autor:
Nicole Yeung, Isabella Orienti, Anahid Ehteda, Jie Liu, Giovanna Farruggia, Han Shen, Patrick Reynolds, Sandra George, Caitlin Ung, Maria Tsoli, Laura Franshaw, Santosh Valvi, Aaminah Khan, Dannielle Upton, David S. Ziegler
Publikováno v:
Neuro-Oncology
Diffuse Intrinsic Pontine Gliomas (DIPGs) are the most devastating of all brain tumors. There are no effective treatments, hence almost all children will die of their tumor within 12-months. There is an urgent need for novel effective therapies for t
Autor:
Aaminah Khan, David S. Ziegler, Denise Yu, Maria Tsoli, Dannielle Upton, Laura D. Gamble, Chelsea Mayoh, Mark R. Burns, Michelle Haber, Ruby Pandher, Murray D. Norris
Publikováno v:
Neuro-Oncology
Diffuse intrinsic pontine glioma (DIPG) is an aggressive paediatric brainstem tumour, with a median survival of less than 1 year. Polyamines are intracellular polycations that control important aspects of cell growth and are often upregulated in canc
Autor:
Nicole Yeung, Caitlin Ung, Patrick Reynolds, Dannielle Upton, Aaminah Khan, Sandra George, Jie Liu, Isabella Orienti, Anahid Ehteda, Santosh Valvi, Giovanna Farruggia, Han Shen, Maria Tsoli, Laura Franshaw, David S. Ziegler, Christa E. Nath
Publikováno v:
Neuro-Oncology
DIPGs are the most devastating of all brain tumors. There are no effective treatments, hence almost all children will die of their tumor within 12 months. There is an urgent need for novel effective therapies for this aggressive tumor. We performed a
Autor:
Aaminah Khan, Laura Gamble, Dannielle Upton, Denise Yu, Anahid Ehteda, Ruby Pandher, Chelsea Mayoh, Mark Burns, Murray Norris, Michelle Haber, Maria Tsoli, David Ziegler
Publikováno v:
Neuro-Oncology
DIPG is an aggressive paediatric brainstem tumour, with a median survival of less than 1 year. Polyamines are intracellular polycations that control important aspects of cell growth and are often upregulated in cancer. Difluoromethylornithine (DFMO)
Publikováno v:
Neuro-Oncology. 23:i19-i19
Diffuse Intrinsic Pontine Glioma (DIPG) is the most aggressive pediatric high-grade glioma with median survival of only 12 months from diagnosis. Current therapies are essentially palliative. The blood-brain barrier (BBB) is a major obstacle, limitin
Autor:
Jie Liu, Steven Yung-Chang Su, Maria Tsoli, Dongpo Cai, Steve Foresto, Neevika Manoharan, Dannielle Upton, Tim Hassall, Sandra George, David S. Ziegler
Publikováno v:
Neuro-Oncology
Diffuse Intrinsic Pontine Gliomas (DIPGs) are a subset of Diffuse Midline Gliomas (DMG) and are the most devastating of all brain tumors. There are no effective treatments and all children die of their tumor within 12-months. We performed a high-thro
Autor:
Anahid Ehteda, Greg M. Arndt, Annafranca Farfalla, Domenico Cassano, Valerio Voliani, Caitlin Ung, Maria Tsoli, Jie Liu, Giuseppe Cirillo, Timothy W. Failes, Dannielle Upton, Salvador Pocoví-Martínez, Maria Kavallaris, David S. Ziegler, Friederike M. Mansfeld, Orazio Vittorio, Christopher J. Katsinas
Publikováno v:
Cancers, Vol 13, Iss 1278, p 1278 (2021)
Cancers
Volume 13
Issue 6
Cancers
Volume 13
Issue 6
Simple Summary Diffuse intrinsic pontine gliomas (DIPGs) are the most aggressive high-grade gliomas known to affect children. Due to the infiltrative nature of the DIPG tumours in the brainstem, they are very difficult to treat. Unfortunately, childr