Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Danni Ran"'
Autor:
Sunyi, Wu, Linwei, Lu, Jianfen, Zhou, Danni, Ran, Songli, Wang, Qianzhu, Xu, Weixia, Xu, Jun, Wang, Yu, Liu, Cao, Xie, Zimiao, Luo, Weiyue, Lu
Publikováno v:
Journal of Controlled Release. 345:685-695
Glioblastoma (GBM) is the most aggressive brain tumor with poor prognosis and frequent recurrence. The blood-brain barrier (BBB), blood-brain tumor barrier (BBTB) hinder the entry of therapeutics into the glioma region. Vasculogenic mimicry (VM) form
Autor:
Cao Xie, Jianfen Zhou, Weiyue Lu, Jiasheng Lu, Songli Wang, Jinyang Li, Zhilan Chai, Danni Ran
Publikováno v:
Journal of Controlled Release. 322:542-554
Owing to the binding capacity to ɑvβ3 integrin overexpressed on glioma, vasculogenic mimicry and neovasculature, the peptide c(RGDyK) has been exploited pervasively to functionalize nanocarriers for targeted delivery of bioactives. The former study
Autor:
Danni Ran, Kuan Jiang, Nana Meng, Xiaoyi Wang, Weiyue Lu, Songli Wang, Yanyu Zhang, Ker Yu, Huan Wang, Ruifeng Wang, Changyou Zhan, Huitong Ruan, Linwei Lu, Diane J. Burgess
Publikováno v:
Journal of Controlled Release. 316:381-392
Liposomes with peptide motifs have been successfully used in glioma-targeted delivery of various general chemotherapy agents. However, their use for the encapsulation of low-toxicity molecularly targeted anticancer agents has been limited. In the pre
Autor:
Kuan Jiang, Yanyu Zhang, Jing Wang, Zhilan Chai, Xuefeng Hu, Weiyue Lu, Cao Xie, Huitong Ruan, Liangfang Zhang, Changyou Zhan, Jinyang Li, Linwei Lu, Ronnie H. Fang, Jianfen Zhou, Danni Ran
Publikováno v:
ACS Nano. 13:5591-5601
The safe and efficient delivery of chemotherapeutic agents remains critical to anticancer therapy. Herein, we report on a targeted drug delivery system based upon a modified cell membrane coating technique and drug nanocrystals (NCs). Specifically, r
Autor:
Danni Ran, Xiaoli Wei, Joseph Wang, Mara Beltrán-Gastélum, Liangfang Zhang, Berta Esteban-Fernández de Ávila, Emil Karshalev, Pavimol Angsantikul, Ronnie H. Fang, Jiarong Zhou
Publikováno v:
Nano Letters. 19:1914-1921
Vaccination represents one of the most effective means of preventing infectious disease. In order to maximize the utility of vaccines, highly potent formulations that are easy to administer and promote high patient compliance are desired. In the pres
Autor:
Hangchang Zhu, Huitong Ruan, Ruifeng Wang, Man Ying, Weiyue Lu, Songli Wang, Zhilan Chai, Mingfei Zhang, Danni Ran, Xiaoyi Wang
Publikováno v:
ACS Applied Materials & Interfaces. 10:19473-19482
The clinical treatment of aggressive glioma has been a great challenge, mainly because of the complexity of the glioma microenvironment and the existence of the blood-brain tumor barrier (BBTB)/blood-brain barrier (BBB), which severely hampers the ef
Autor:
Liangfang Zhang, Huitong Ruan, Zhilan Chai, Changyou Zhan, Danni Ran, Ronnie H. Fang, Xuefeng Hu, Bingxia Su, Xiaoli Wei, Kuan Jiang, Linwei Lu, Weiyue Lu
Publikováno v:
Journal of Controlled Release. 264:102-111
The blood brain barrier separates the circulating blood from the extracellular fluid in the central nervous system and thus presents an essential obstacle to brain transport of therapeutics. Herein, we report on an effective brain-targeted drug deliv
Publikováno v:
ACS Applied Materials & Interfaces. 9:24462-24475
Tumor-homing peptides have been widely used to mediate active targeted drug delivery. l-AE is a reported targeting peptide demonstrating high binding affinity to epidermal growth factor receptor (EGFR) and mutation variant III (EGFRvIII) overexpresse
Autor:
Jinyang, Li, Zhilan, Chai, Jiasheng, Lu, Cao, Xie, Danni, Ran, Songli, Wang, Jianfen, Zhou, Weiyue, Lu
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 322
Owing to the binding capacity to ɑ
Autor:
Sunyi Wu, Cao Xie, Mao Jiani, Jinyang Li, Weiyue Lu, Jianfen Zhou, Zhilan Chai, Changyou Zhan, Danni Ran, Linwei Lu, Yanyu Zhang
Publikováno v:
Theranostics
Uncontrollable cell proliferation and irreversible neurological damage make glioma one of the most deadly diseases in clinic. Besides the multiple biological barriers, glioma stem cells (GSCs) that are responsible for the maintenance and recurrence o