Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Dannette K. Hansen"'
Autor:
Herbert W. Behlow, Michael L. Avery, Kenneth W. Otis, Dennis O. Scott, Suzanne M. Broward-Partin, Thomas N. Thompson, Dannette K. Hansen
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 45:71-77
Combinatorial synthesis and high-throughput pharmacology screening have greatly increased compound throughput in modern drug-discovery programs. For CNS drugs, it is also important to determine permeability to the blood--brain barrier. Yet, given the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09da317121e62a7a1793ad5ce0969c14
https://doi.org/10.1016/s1056-8719(01)00120-4
https://doi.org/10.1016/s1056-8719(01)00120-4
Autor:
Dannette K. Hansen, Susan M. Lunte
Publikováno v:
Journal of Chromatography A. 781:81-89
Kynurenic acid (KA) is an excitatory amino acid receptor antagonist that is believed to play an important role in a host of diseases of the neuropsychiatric and central nervous system. A method for the determination of KA in microdialysate samples us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b14506b39e344e7178c6bc4fa257719
https://doi.org/10.1016/s0021-9673(97)00534-7
https://doi.org/10.1016/s0021-9673(97)00534-7
ADME (adsorption, distribution, metabolism, elimination) studies on new drug entities, toxicological studies on environmental contaminants, and evaluation of chemicals in the workplace all involve gathering similar types of information. Such studies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f5cd4580013fb293d0281e7b0cd3d15
https://europepmc.org/articles/PMC2519818/
https://europepmc.org/articles/PMC2519818/
