Sirt1 gene confers Adriamycin resistance in DLBCL via activating the PCG-1α mitochondrial metabolic pathway

Autor: Qin Fang, Jishi Wang, Zhen Zhou, Danna Wei, Peifan Li, Ping Liu, Ping Wang, Jun Wang, Dan Ma, Zhong Qin

Publikováno v: Aging (Albany NY)

Sirt1 is closely related to cells aging, and Sirt1 also plays an important role in diffuse large B-cell lymphoma (DLBCL). However, its mechanism remains unclear. Therefore, we investigated the mechanism of Sirt1 mediated drug-resistance in DLBCL, whi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e975cf1b3d17d34f57b65077143bf91a
http://europepmc.org/articles/PMC7343448

Isolation and Characterization of a Biosurfactant Producing Strain Planococcus sp. XW-1 from the Cold Marine Environment

Autor: Ping Guo, Weiwei Xu, Shi Tang, Binxia Cao, Danna Wei, Manxia Zhang, Jianguo Lin, Wei Li

Publikováno v: International Journal of Environmental Research and Public Health, Vol 19, Iss 782, p 782 (2022)
International Journal of Environmental Research and Public Health; Volume 19; Issue 2; Pages: 782

One cold-adapted strain, named Planococcus sp. XW-1, was isolated from the Yellow Sea. The strain can produce biosurfactant with petroleum as sole source of carbon at low temperature (4 °C). The biosurfactant was identified as glycolipid-type biosur

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfa4d007a29d06b3bbe983ada9546a33
https://www.mdpi.com/1660-4601/19/2/782

CAY10683 and imatinib have synergistic effects in overcoming imatinib resistance via HDAC2 inhibition in chronic myeloid leukemia

Autor: Tianzhuo Zhang, Danna Wei, Kunlin Yu, Tingting Lu, Dan Ma, Weili Wang, Jishi Wang, Zhaoyuan Zhang, Qin Fang

Publikováno v: RSC Advances. 10:828-844

Imatinib (IM) is utilized for targeting the BCR–ABL fusion protein and as such, chronic myeloid leukemia (CML) is considered to be a curable disorder for which patients can achieve a long survival. However, 15–20% CML cases end up with IM resista

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::061ea36609ad6af7db226a76ac9531a8
https://doi.org/10.1039/c9ra07971h

Synergistic activity of imatinib and AR-42 against chronic myeloid leukemia cells mainly through HDAC1 inhibition

Autor: Jie Xiong, Weili Wang, Dan Ma, Zhaoyuan Zhang, Kunlin Yu, Jishi Wang, Tianzhuo Zhang, Tingting Lu, Danna Wei, Qin Fang

Publikováno v: Life Sciences. 211:224-237

Aims The aim of this study was to investigate the combinatorial effects of IM and a novel HDAC inhibitor AR-42 on the proliferation, apoptosis, cell cycle arrest, migration and invasion of CML cells, and to explore the underlying mechanisms. Main met

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5abc72a480eea9f24205a6781048fc48
https://doi.org/10.1016/j.lfs.2018.09.040

CAY10683 and imatinib have synergistic effects in overcoming imatinib resistance

Autor: Tianzhuo, Zhang, Danna, Wei, Tingting, Lu, Dan, Ma, Kunlin, Yu, Qin, Fang, Zhaoyuan, Zhang, Weili, Wang, Jishi, Wang

Publikováno v: RSC advances. 10(2)

Imatinib (IM) is utilized for targeting the BCR-ABL fusion protein and as such, chronic myeloid leukemia (CML) is considered to be a curable disorder for which patients can achieve a long survival. However, 15-20% CML cases end up with IM resistance

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::bf53707293dd8f15bec6f11f274c083b
https://pubmed.ncbi.nlm.nih.gov/35494464