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Akademický článek

1,25-Dihydroxyvitamin D inhibits hepatic diacyglycerol accumulation and ameliorates metabolic dysfunction in polycystic ovary syndrome rat models

Autor: Xin Yuan, Jianshu Yang, Danlin Sun, Kaiming Luo, Xiaohong Jiang, Long Wang, Shoukui Xiang, Yijie Jiang, Kele Ge, Zhiyang Zhou, Bowen Li, Fei Hua

Publikováno v: Frontiers in Pharmacology, Vol 14 (2023)

Introduction: We aimed to evaluate the influence of 1,25-dihydroxyvitamin D (1,25(OH)2D) on metabolic dysfunction and elucidate its underlying mechanism using a rat model of polycystic ovary syndrome (PCOS).Methods: Twenty-four Sprague-Dawley rats we

Externí odkaz: https://doaj.org/article/44f042a742c3486dac62c3132ce6b438

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Excess Molar Volume, Viscosity and Refractive Index for Binary Mixtures of Methyl Laurate with n-Octane, Iso-Octane or Ethyl Cyclohexane

Autor: Dan Li, Yan Pang, Jingying Wang, Danlin Sun, Xuena Zhang, Danwei Yue, Longxia Hao

Publikováno v: Journal of Solution Chemistry. 51:752-767

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0375d64d3edc5045a544467611fc69c6
https://doi.org/10.1007/s10953-022-01160-4

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Evaluation of the Small-molecule BRD4 Degrader CFT-2718 in Small-cell Lung Cancer and Pancreatic Cancer Models

Autor: David A. Proia, Zhigang Tu, Linda Lee, Ryan E. Michael, Christopher G. Nasveschuk, Danlin Sun, Mark E. Fitzgerald, Alexander Y. Deneka, Stewart L. Fisher, Anna C. Lilly, Anna S. Nikonova, Peishan Zhang, Andrew J. Phillips, Erica A. Golemis

Publikováno v: Mol Cancer Ther

Targeted, catalytic degradation of oncoproteins using heterobifunctional small molecules is an attractive modality, particularly for hematologic malignancies, which are often initiated by aberrant transcription factors and are challenging to drug wit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64abfe3d18e64103ac9017aeed1e325c
https://doi.org/10.1158/1535-7163.mct-20-0831

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Proliferative signaling by ERBB proteins and RAF/MEK/ERK effectors in polycystic kidney disease

Autor: Danlin Sun, Anna S. Nikonova, Mitchell I. Parker, Erica A. Golemis

Publikováno v: Cell Signal

A primary pathological feature of polycystic kidney disease (PKD) is the hyperproliferation of epithelial cells in renal tubules, resulting in formation of fluid-filled cysts. The proliferative aspects of the two major forms of PKD—autosomal domina

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11bfd5d2de0c454dc2e36eb44496bf59
https://pubmed.ncbi.nlm.nih.gov/31830556

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