Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Danliang Ho"'
Autor:
Guanhua Zhu, Yu A. Guo, Danliang Ho, Polly Poon, Zhong Wee Poh, Pui Mun Wong, Anna Gan, Mei Mei Chang, Dimitrios Kleftogiannis, Yi Ting Lau, Brenda Tay, Wan Jun Lim, Clarinda Chua, Tira J. Tan, Si-Lin Koo, Dawn Q. Chong, Yoon Sim Yap, Iain Tan, Sarah Ng, Anders J. Skanderup
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Circulating tumour DNA (ctDNA) represents a non-invasive option to monitor cancer progression. Here, the authors perform deep sequencing of plasma cell-free DNA, and find that nucleosome-dependent cfDNA degradation at 6 specific regulatory regions is
Externí odkaz:
https://doaj.org/article/3c974350bb8a41b0a12aa9c3b0c56857
Autor:
Yu A. Guo, Polly Poon, Zhong Wee Poh, Wan Jun Lim, Iain Tan, Brenda Tay, Tira Jing Ying Tan, Anders Jacobsen Skanderup, Pui Mun Wong, Dawn Qq Chong, Danliang Ho, Sarah Ng, Si-Lin Koo, Guanhua Zhu, Yoon Sim Yap, Yi Ting Lau, Dimitrios Kleftogiannis, Anna Gan, Mei Mei Chang, Clarinda Chua
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Profiling of circulating tumor DNA (ctDNA) may offer a non-invasive approach to monitor disease progression. Here, we develop a quantitative method, exploiting local tissue-specific cell-free DNA (cfDNA) degradation patterns, that accurately estimate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5182e4eaeb9734249fc56062229020e
https://doi.org/10.1038/s41467-021-22463-y
https://doi.org/10.1038/s41467-021-22463-y
Publikováno v:
CHIL
Colorectal cancer recurrence is a major clinical problem - around 30-40% of patients who are treated with curative intent surgery will experience cancer relapse. Proactive prognostication is critical for early detection and treatment of recurrence. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a08571fa07666ede33776ed1ed9b826a
https://doi.org/10.1145/3450439.3451868
https://doi.org/10.1145/3450439.3451868
Publikováno v:
HealthCom
Colorectal cancer is among the top three most commonly occurring cancers worldwide, and around 30-40% of patients treated by curative intent surgery will experience cancer recurrence. Proactive prognostication would enable clinicians to better plan t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5975501165017a1c84f4c321c0979afe
https://doi.org/10.1109/healthcom49281.2021.9398977
https://doi.org/10.1109/healthcom49281.2021.9398977
Autor:
Jun Xian Liew, Swee Ho Lim, Raymond Ng, Iain Beehuat Tan, Benita Kiat-Tee Tan, Gek San Tan, Tony Kiat Hon Lim, Yoon Sim Yap, Danliang Ho, Chih Chuan Shih, Ann Siew-Gek Lee, Sarah Ng, Polly Suk Yean Poon, Dimitrios Kleftogiannis, Anna Gan, Kiang Hiong Tay
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Analysis of circulating cell-free DNA (cfDNA) has opened new opportunities for characterizing tumour mutational landscapes with many applications in genomic-driven oncology. We developed a customized targeted cfDNA sequencing approach for breast canc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bc05c2d59927389e6b6e9768ad4aadf
http://europepmc.org/articles/PMC7544894
http://europepmc.org/articles/PMC7544894
Autor:
Claramae Shulyn Chia, Iain Beehuat Tan, Clarinda Chua, Wei Lin Goh, Johnny Ong, Danliang Ho, Eileen Poon, Woei Loon Tan, Mohamad Farid Bin Harunal Ras, Sarah B Ng, Nagavalli Somasundaram, Jiancheng Hong, Richard Quek, Anna Gan, Rebecca Lim, Melissa Ching Ching Teo, Wan Jun Lim, Grace Hwei Ching Tan, Jason Yongsheng Chan
PURPOSE: Gastrointestinal stromal tumors (GISTs) are characterized by primary mutations (PM) in KIT or PDGFRA genes. Under pharmacological pressure secondary mutations (SM) develop resulting in resistance to treatment. Our group developed a multiplex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6103ac5e119bfe51d010ce5c35fd3ed
https://doi.org/10.1101/481622
https://doi.org/10.1101/481622
Autor:
Steve Rozen, Sarah B Ng, William F. Burkholder, Anna Gan, Alexander Y. F. Chung, Kiat Hon Lim, Iain Beehuat Tan, Polly Sy Poon, Matthew C.H. Ng, Su Pin Choo, Clarinda Chua, Patrick Tan, Danliang Ho, Melissa Ching Ching Teo, Cherylin Fu, Wei Qiang Leow, Si-Lin Koo, Mark T. C. Wong
Publikováno v:
Scientific Reports
Circulating tumour DNA (ctDNA) has the potential to be a specific biomarker for the monitoring of tumours in patients with colorectal cancer (CRC). Here, our aim was to develop a personalised surveillance strategy to monitor the clinical course of CR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68a18bfd559230f7184d1eb6a0a72f80
https://doi.org/10.1038/srep40737
https://doi.org/10.1038/srep40737
Publikováno v:
Annals of Oncology. 30:i10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a15a577e3a68225377563958f3bdd78
https://doi.org/10.1093/annonc/mdz030.002
https://doi.org/10.1093/annonc/mdz030.002
Autor:
Kiat Hon Lim, Evan W. Newell, Charles J. Vaske, Jonathan Göke, Etienne Becht, Shahrooz Rabizadeh, Stephen C. Benz, Andrew Nguyen, Saranya Thangaraju, Clarinda Chua, Iain Beehuat Tan, Yulia Newton, Danliang Ho, Choong Leong Tang, Bram Lim, Joe Poh Sheng Yeong, Si-Lin Koo, Ronnie Mathew, Christopher Szeto, Anders Jacobsen Skanderup
Publikováno v:
Journal of Clinical Oncology. 36:e15597-e15597
e15597Background: Responses to anti-PD1 is ~35% in microsatellite unstable (MSI-h) and near 0% in microsatellite stable (MSS) Colorectal cancer (CRC). Understanding the composition of immune cell p...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d0ace1541a56739aacad61a6df9b24a8
https://doi.org/10.1200/jco.2018.36.15_suppl.e15597
https://doi.org/10.1200/jco.2018.36.15_suppl.e15597
Autor:
Chimedsuren Javzandulam, Qiangchuan Hou, Weiqiang Huang, Yuan-Kun Lee, Danliang Ho, Dongxue Huo, Choijilsuren Narangerel, Menghebilige, Yi Zheng, Jianmin Qiao, Jiachao Zhang, Eileen Y. Koh, Lifeng Wang, Jirimutu, Heping Zhang, Zhuang Guo, Angela An Qi Lim
Publikováno v:
Scientific Reports
Historically, the Mongol Empire ranks among the world's largest contiguous empires, and the Mongolians developed their unique lifestyle and diet over thousands of years. In this study, the intestinal microbiota of Mongolians residing in Ulan Bator, T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d0558739770a93cca1297eb36efcb61
http://europepmc.org/articles/PMC4023135
http://europepmc.org/articles/PMC4023135