Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Daniyah A Almarghalani"'
Autor:
Daniyah A Almarghalani, Sai H.S. Boddu, Mohammad Ali, Akhila Kondaka, Devin Ta, Rayyan A Shah, Zahoor A Shah
Publikováno v:
Neural Regeneration Research, Vol 17, Iss 8, Pp 1717-1725 (2022)
Intracerebral hemorrhage (ICH) is a subtype of stroke associated with higher rates of mortality. Currently, no effective drug treatment is available for ICH. The molecular pathways following ICH are complicated and diverse. Nucleic acid therapeutics
Externí odkaz:
https://doaj.org/article/135c8707d4434edb98498d9091f21a97
Autor:
Ahad Amer Alsaiari, Fawaz M. Almufarriji, Ali Hazazi, Daniyah A. Almarghalani, Maha Mahfouz Bakhuraysah, Amani A. Alrehaili, Shatha M. Algethami, Khulood A. Almehmadi, Fayez Saeed Bahwerth, Mohammed Ageeli Hakami
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-19 (2024)
Abstract Cervical cancer begins in the cells lining the cervix and is caused by persistent infection with certain types of human papillomavirus (HPV). Initially, it has no symptoms, and later it causes pelvic pain, abnormal vaginal bleeding, and pain
Externí odkaz:
https://doaj.org/article/5ef780b016ee417d8d24fab0b4429d1f
Autor:
Faisal F. Alamri, Daniyah A. Almarghalani, Eman A. Alraddadi, Abdullah Alharbi, Hajar S. Algarni, Oyoon M. Mulla, Abdullah M. Alhazmi, Turki A. Alotaibi, Deema H. Beheiry, Abdullah S. Alsubaie, Ahmed Alkhiri, Yasser Alatawi, Mohammad S. Alzahrani, Alqassem Y. Hakami, Aser Alamri, Khalid Al Sulaiman
Publikováno v:
Saudi Pharmaceutical Journal, Vol 32, Iss 6, Pp 102082- (2024)
Background and Objective: Glucose-Potassium Ratio (GPR) has emerged as a biomarker in several pathophysiological conditions. However, the association between GPR and long-term outcomes in stroke patients has not been investigated. Our study evaluated
Externí odkaz:
https://doaj.org/article/902bf339692e4659bd2ec89139243b94
Autor:
Daniyah A. Almarghalani, Ghaith A. Bahader, Mohammad Ali, L. M. Viranga Tillekeratne, Zahoor A. Shah
Publikováno v:
Pharmaceuticals, Vol 17, Iss 1, p 114 (2024)
Neuroinflammation after intracerebral hemorrhage (ICH) is a crucial factor that determines the extent of the injury. Cofilin is a cytoskeleton-associated protein that drives neuroinflammation and microglia activation. A novel cofilin inhibitor (CI) s
Externí odkaz:
https://doaj.org/article/c666ceb9c7b34d37870f239f0fc9cd09
Publikováno v:
Cells, Vol 13, Iss 2, p 188 (2024)
This comprehensive review explores the complex role of cofilin, an actin-binding protein, across various neurodegenerative diseases (Alzheimer’s, Parkinson’s, schizophrenia, amyotrophic lateral sclerosis (ALS), Huntington’s) and stroke. Cofilin
Externí odkaz:
https://doaj.org/article/9ec1d9d39de54eb098536a0b78ad6bef
Publikováno v:
Biology, Vol 12, Iss 4, p 630 (2023)
Microglial activation and failure of the antioxidant defense mechanisms are major hallmarks in different brain injuries, particularly traumatic brain injury (TBI). Cofilin is a cytoskeleton-associated protein involved in actin binding and severing. I
Externí odkaz:
https://doaj.org/article/ed1c9aeb593e494c908623fed7a9ca72
Publikováno v:
Cells, Vol 12, Iss 8, p 1153 (2023)
Intracerebral hemorrhage (ICH) is a significant health concern associated with high mortality. Cofilin plays a crucial role in stress conditions, but its signaling following ICH in a longitudinal study is yet to be ascertained. In the present study,
Externí odkaz:
https://doaj.org/article/0cbd64fb5c6a4eb2973903240b95abcf
Autor:
Shoaib Manzoor, Daniyah A. Almarghalani, Antonisamy William James, Md Kausar Raza, Tasneem Kausar, Shahid M. Nayeem, Nasimul Hoda, Zahoor A. Shah
Publikováno v:
Pharmaceutical research.
Neuroprotection is a precise target for the treatment of neurodegenerative diseases, ischemic stroke, and traumatic brain injury. Pyrimidine and its derivatives have been proven to use antiviral, anticancer, antioxidant, and antimicrobial activity pr
Autor:
Saleh I. Alaqel, Samkeliso Dlamini, Daniyah A. Almarghalani, Arjun Shettigar, Qasim Alhadidi, Sinali H. Kodithuwakku, Creed Stary, L. M. Viranga Tillekeratne, Zahoor A. Shah
Publikováno v:
ACS Chem Neurosci
Intracerebral hemorrhage (ICH) is devastating among stroke types with high mortality. To date, not a single therapeutic intervention has been successful. Cofilin plays a critical role in inflammation and cell death. In the current study, we embarked
Autor:
Zahoor A. Shah, Kevin M. Nash, Qasim Alhadidi, Ghaith A. Bahader, Marcia F. McInerney, Daniyah A. Almarghalani
Publikováno v:
Neurochem Int
Diabetes Mellitus (DM) is a major comorbid condition that increases susceptibility to stroke. Intracerebral hemorrhage (ICH), a devastating type of stroke, accounts for only 13% of the total stroke cases but is associated with higher mortality. Multi