Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Danitza Rebolledo"'
Autor:
Angel Cayo, Whitney Venturini, Danitza Rebolledo-Mira, Rodrigo Moore-Carrasco, Andrés A. Herrada, Estefanía Nova-Lamperti, Claudio Valenzuela, Nelson E. Brown
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 11; Pages: 9284
Despite not dividing, senescent cells acquire the ability to synthesize and secrete a plethora of bioactive molecules, a feature known as the senescence-associated secretory phenotype (SASP). In addition, senescent cells often upregulate autophagy, a
Autor:
Claudio A. Valenzuela, Danitza Rebolledo, Angel Cayo, Whitney Venturini, Raúl Segovia, Rodrigo Moore-Carrasco, Nelson Brown
Publikováno v:
Cancer Research. 83:5983-5983
Introduction: The initial transition from a proliferative to a senescent state is accompanied by a reduction in the activity of the cyclin-cyclin-dependent kinase (CDK) complexes, which in turn could be explained by the activation of the p53-p21CIP1/