Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Danique E.M. Duits"'
Autor:
Olga S. Blomberg, Kevin Kos, Lorenzo Spagnuolo, Olga I. Isaeva, Hannah Garner, Max D. Wellenstein, Noor Bakker, Danique E.M. Duits, Kelly Kersten, Sjoerd Klarenbeek, Cheei-Sing Hau, Daphne Kaldenbach, Elisabeth A.M. Raeven, Kim Vrijland, Marleen Kok, Karin E. de Visser
Publikováno v:
OncoImmunology, Vol 12, Iss 1 (2023)
ABSTRACTThe clinical successes of immune checkpoint blockade (ICB) in advanced cancer patients have recently spurred the clinical implementation of ICB in the neoadjuvant and perioperative setting. However, how neoadjuvant ICB therapy affects the sys
Externí odkaz:
https://doaj.org/article/b656e036ddb5458b8a3bb50ca339a61b
Autor:
Kevin Kos, Muhammad A. Aslam, Rieneke van de Ven, Max D. Wellenstein, Wietske Pieters, Antoinette van Weverwijk, Danique E.M. Duits, Kim van Pul, Cheei-Sing Hau, Kim Vrijland, Daphne Kaldenbach, Elisabeth A.M. Raeven, Sergio A. Quezada, Rudi Beyaert, Heinz Jacobs, Tanja D. de Gruijl, Karin E. de Visser
Publikováno v:
CELL REPORTS
Cell Reports, 38(9):110447. Cell Press
Kos, K, Aslam, M A, van de Ven, R, Wellenstein, M D, Pieters, W, van Weverwijk, A, Duits, D E M, van Pul, K, Hau, C-S, Vrijland, K, Kaldenbach, D, Raeven, E A M, Quezada, S A, Beyaert, R, Jacobs, H, de Gruijl, T D & de Visser, K E 2022, ' Tumor-educated Tregs drive organ-specific metastasis in breast cancer by impairing NK cells in the lymph node niche ', Cell Reports, vol. 38, no. 9, 110447 . https://doi.org/10.1016/j.celrep.2022.110447
Cell Reports, 38(9):110447. Cell Press
Kos, K, Aslam, M A, van de Ven, R, Wellenstein, M D, Pieters, W, van Weverwijk, A, Duits, D E M, van Pul, K, Hau, C-S, Vrijland, K, Kaldenbach, D, Raeven, E A M, Quezada, S A, Beyaert, R, Jacobs, H, de Gruijl, T D & de Visser, K E 2022, ' Tumor-educated Tregs drive organ-specific metastasis in breast cancer by impairing NK cells in the lymph node niche ', Cell Reports, vol. 38, no. 9, 110447 . https://doi.org/10.1016/j.celrep.2022.110447
Breast cancer is accompanied by systemic immunosuppression, which facilitates metastasis formation, but how this shapes organotropism of metastasis is poorly understood. Here, we investigate the impact of mammary tumorigenesis on regulatory T cells (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e23db27f6ed5bdc3970977687df72d7
https://doi.org/10.1016/j.celrep.2022.110447
https://doi.org/10.1016/j.celrep.2022.110447
Autor:
Lodewyk F. A. Wessels, Seth B. Coffelt, Karin E. de Visser, Iris de Rink, Linda Henneman, Ingrid van der Heijden, Eva Schut, Kim Vrijland, Cheei-Sing Hau, Renske de Korte-Grimmerink, Danique E.M. Duits, Anne Paulien Drenth, Ton N. Schumacher, Jos Jonkers, Sjors M. Kas, Max D. Wellenstein, Maarten Slagter, Stefan Prekovic, Martine H. van Miltenburg, Wilbert Zwart
Publikováno v:
Nature
Cancer-associated systemic inflammation is strongly linked to poor disease outcome in patients with cancer1,2. For most human epithelial tumour types, high systemic neutrophil-to-lymphocyte ratios are associated with poor overall survival3, and exper
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0e8194c0d59e9e5b9885d150a2961f0
https://doi.org/10.1038/s41586-019-1450-6
https://doi.org/10.1038/s41586-019-1450-6