Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Danilo Janjic"'
Autor:
Sarah Cairo Notari, Julia Sader, Marie-Claude Audétat, Mathieu Nendaz, Johanna Sommer, Anne Catherine Pereira Miozzari, Nathalie Caire Fon, Danilo Janjic
Publikováno v:
International Journal of Clinical Practice
Background Most consultations in primary care involve patients suffering from multimorbidity. Nevertheless, few studies exist on the clinical reasoning processes of general practitioners (GPs) during the follow‐up of these patients. The aim of this
Publikováno v:
Revue medicale suisse. 9(386)
The aim of this article is to help primary care teachers to instruct students' recommendations for drug prescription. Teaching drug prescription covers many aspects of primary care physicians' profession: establishing the correct diagnosis, choosing
Publikováno v:
Pancreas. 13:166-172
The viability of islets of Langerhans prior to grafting is believed to influence the clinical outcome of islet transplantation. To determine whether oxidative stress occurs during the isolation-purification procedure as well as during tissue culture
Publikováno v:
Primary Care, Vol. 14, No 3 (2014) pp. 50-51
Depuis juin 2012 les societes academiques de diabetologie europeennes et americaines (EASD, ADA) ont conjointement formule de nouvelles recommandations pour le traitement de l’hyperglycemie chez les diabetiques de type 2 [1]. En preambule, nous pre
Publikováno v:
PrimaryCare. 14:50-51
Publikováno v:
Endocrinology, Vol. 130, No 1 (1992) pp. 167-178
New insulin-secreting cell lines (INS-1 and INS-2) were established from cells isolated from an x-ray-induced rat transplantable insulinoma. The continuous growth of these cells was found to be dependent on the reducing agent 2-mercaptoethanol. Remov
Autor:
Claes B. Wollheim, Pierre Maechler, Anne-Sofie Annen, Nobuo Sekine, Danilo Janjic, Clarissa Bartley
Publikováno v:
Biochemical pharmacology. 57(6)
Generation of free radicals is thought to mediate the cytotoxic action of alloxan on the pancreatic β-cell. In this investigation, the early effects of alloxan on cell function were studied. When INS-1D insulinoma cells were exposed to alloxan (1 mM
Autor:
Claes B. Wollheim, Danilo Janjic
Publikováno v:
European journal of biochemistry. 210(1)
The role of glutathione (GSH) in the differentiated state of insulin-secreting cells was studied using 2-mercaptoethanol as a means of varying intracellular GSH levels. 2-Mercaptoethanol (50 microM) caused a marked increase of GSH in two rat insulino
Publikováno v:
Journal of Endocrinological Investigation. 8:423-426
The involvement of the Ca2+ binding protein, calmodulin, in the regulation of insulin release was studied. Calmodulin was measured in isolated rat islets, rat insulinoma cells, the insulin secreting cell line (RINm5F) and in islets isolated from norm
Publikováno v:
Diabetes. 32:993-1000
Islet culture at a low glucose concentration results in a progressive impairment of glucose-induced insulin release. The role of Ca2+ in this defect was studied by comparing rat islets cultured for 6 days either at 8.3 mM (control) or 2.8 mM glucose.