Application of Transthoracic Echocardiography for Cardiac Safety Evaluation in the Clinical Development Process of Vaccines Against Streptococcus pyogenes

Autor: Usman Nakakana, Alimamy Serry-Bangura, Bassey Effiom Edem, Pietro Tessitore, Leonardo Di Cesare, Danilo Gomes Moriel, Audino Podda, Iris Sarah De Ryck, Ashwani Kumar Arora

Publikováno v: Drugs in R&D, Vol 24, Iss 1, Pp 1-12 (2024)

Abstract Superficial infections with Streptococcus pyogenes (Strep A), pharyngitis and impetigo can induce acute rheumatic fever, an autoimmune sequela manifesting mostly with arthritis and rheumatic carditis. Valvular heart damage can persist or adv

Externí odkaz: https://doaj.org/article/23154e1095a44ff6b94abfb25a71616c

Effect of feeding methods on the astaxanthin production by Phaffia rhodozyma in fed-batch process

Autor: Danilo Gomes Moriel, Miriam Blumel Chociai, Iara Maria Pereira Machado, José Domingos Fontana, Tania Maria Bordin Bonfim

Publikováno v: Brazilian Archives of Biology and Technology, Vol 48, Iss 3, Pp 397-401 (2005)

The effect of feeding methods on the production of astaxanthin by the yeast Phaffia rhodozyma ATCC 24202 was studied, using continuous and pulsed fed-batch processes and low cost materials as substrates (sugar cane juice and urea). In continuous fed-

Externí odkaz: https://doaj.org/article/0ad02f70289f4e56b60bfdde4a7bcac6

The serum resistome of a globally disseminated multidrug resistant uropathogenic Escherichia coli clone.

Autor: Minh-Duy Phan, Kate M Peters, Sohinee Sarkar, Samuel W Lukowski, Luke P Allsopp, Danilo Gomes Moriel, Maud E S Achard, Makrina Totsika, Vikki M Marshall, Mathew Upton, Scott A Beatson, Mark A Schembri

Publikováno v: PLoS Genetics, Vol 9, Iss 10, p e1003834 (2013)

Escherichia coli ST131 is a globally disseminated, multidrug resistant clone responsible for a high proportion of urinary tract and bloodstream infections. The rapid emergence and successful spread of E. coli ST131 is strongly associated with antibio

Externí odkaz: https://doaj.org/article/69d77e522fe44131b6bcf38b880cdd43

Molecular and structural characterization of a novel Escherichia coli interleukin receptor mimic protein

Autor: Begoña Heras, Samantha J. Dando, Mark A. Schembri, Jason J. Paxman, Glen C. Ulett, Matthew J. Sullivan, Scott A. Beatson, Lendl Tan, Danilo Gomes Moriel, Alvin W. Lo

Publikováno v: mBio, Vol 7, Iss 2, p e02046-15 (2016)
mBio
mBio, Vol 7, Iss 2 (2016)

Urinary tract infection (UTI) is a disease of extremely high incidence in both community and nosocomial settings. UTIs cause significant morbidity and mortality, with approximately 150 million cases globally per year. Uropathogenic Escherichia coli (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8464f5f21fcf23435927153b67e0e2cb

Structure, dynamics and immunogenicity of a catalytically inactive CXC Chemokine-degrading Protease SpyCEP from Streptococcus pyogenes

Autor: Giuliano Bensi, Danilo Gomes Moriel, Stephen Matthews, Guido Grandi, Danuta Mossakowska, Francesca Mancini, Sarah L. Rouse, Yingqi Xu, Max Pearson, Enrico Malito, Emiliano Chiarot, Francesca Micoli, Shiranee Sriskandan, Francesca Abate, Immaculada Margarit, Matthew J. Bottomley, Sophie McKenna, James E. Pease

Publikováno v: Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal, Vol 18, Iss, Pp 650-660 (2020)
'Computational and Structural Biotechnology Journal ', vol: 18, pages: 650-660 (2020)

Graphical abstract
Over 18 million disease cases and half a million deaths worldwide are estimated to be caused annually by Group A Streptococcus. A vaccine to prevent GAS disease is urgently needed. SpyCEP (Streptococcus pyogenes Cell-Envelope

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bc509c7640f9e155434611c67601fb3
http://hdl.handle.net/10044/1/78264