Unique structural features of a bacterial autotransporter adhesin suggest mechanisms for interaction with host macromolecules

Autor: Jason J. Paxman, Alvin W. Lo, Matthew J. Sullivan, Santosh Panjikar, Michael Kuiper, Andrew E. Whitten, Geqing Wang, Chi-Hao Luan, Danilo G. Moriel, Lendl Tan, Kate M. Peters, Minh-Duy Phan, Christine L. Gee, Glen C. Ulett, Mark A. Schembri, Begoña Heras

Publikováno v: Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)

Autotransporter proteins are localised to the bacterial surface and promote colonisation of host epithelial surfaces. Here, the authors present the crystal structure of autotransporter UpaB and show evidence for distinct binding sites for glycosamino

Externí odkaz: https://doaj.org/article/84181b0a975c40f082db3fb0320d1436

Bioinformatic and Molecular Analysis of Inverse Autotransporters from Escherichia coli

Autor: Kelvin G. K. Goh, Danilo G. Moriel, Steven J. Hancock, Minh-Duy Phan, Mark A. Schembri

Publikováno v: mSphere, Vol 4, Iss 4 (2019)

ABSTRACT Proteins secreted by the type V secretion system possess multiple functions, including the capacity to mediate adhesion, aggregation, and biolfilm formation. The type V secretion system can be divided into five subclasses, one of which is th

Externí odkaz: https://doaj.org/article/5a2bce43cc6740758735a697a788792f

Molecular and Structural Characterization of a Novel Escherichia coli Interleukin Receptor Mimic Protein

Autor: Danilo G. Moriel, Begoña Heras, Jason J. Paxman, Alvin W. Lo, Lendl Tan, Matthew J. Sullivan, Samantha J. Dando, Scott A. Beatson, Glen C. Ulett, Mark A. Schembri

Publikováno v: mBio, Vol 7, Iss 2 (2016)

ABSTRACT Urinary tract infection (UTI) is a disease of extremely high incidence in both community and nosocomial settings. UTIs cause significant morbidity and mortality, with approximately 150 million cases globally per year. Uropathogenic Escherich

Externí odkaz: https://doaj.org/article/fc01d4caa3354732be0b81f157eb1bd7

Isolation and characterization of Saccharomyces cerevisiae strains of winery interest

Autor: Cyntia M. T. Fadel Picheth, Thais M. Guimarães, Iara Maria Pereira Machado, Danilo G. Moriel, Tania Maria Bordin Bonfim

Publikováno v: Revista Brasileira de Ciências Farmacêuticas; Vol. 42 Núm. 1 (2006); 119-126
Revista Brasileira de Ciências Farmacêuticas; v. 42 n. 1 (2006); 119-126
Revista Brasileira de Ciências Farmacêuticas; Vol. 42 No. 1 (2006); 119-126
RBCF. Revista Brasileira de Ciências Farmacêuticas
Universidade de São Paulo (USP)
instacron:USP

Despite the availability of several Saccharomyces cerevisiae commercial strains intended for wine production, strains isolated from winery regions are usually more adapted to their own climatic conditions, grapes and also partially responsible for pa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aff66aa6f56b54e03440b96ca7d25c71
https://doi.org/10.1590/s1516-93322006000100013

Differential Regulation of the Surface-Exposed and Secreted SslE Lipoprotein in Extraintestinal Pathogenic Escherichia coli.

Autor: Lendl Tan, Danilo G Moriel, Makrina Totsika, Scott A Beatson, Mark A Schembri

Publikováno v: PLoS ONE, Vol 11, Iss 9, p e0162391 (2016)

Extra-intestinal pathogenic Escherichia coli (ExPEC) are responsible for diverse infections including meningitis, sepsis and urinary tract infections. The alarming rise in anti-microbial resistance amongst ExPEC complicates treatment and has highligh

Externí odkaz: https://doaj.org/article/38fd54ffa65941dda6c5dfd6269fb4a2