Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Danika Wullner"'
Autor:
Vibha Jawa, Steven J. Swanson, Narendra Chirmule, Theresa J. Goletz, Danika Wullner, Andrew J. Kuck, Lei Zhou, Erica Bramhall
Publikováno v:
Clinical Immunology. 137:5-14
An immune response to a biotherapeutic can be induced when the therapeutic is processed and presented by antigen presenting cell to T helper cells. This study evaluates the performance of an in vitro assay that can elicit antigen specific effector T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aafc9a1d39b476313a672b7c7851da43
https://doi.org/10.1016/j.clim.2010.06.018
https://doi.org/10.1016/j.clim.2010.06.018
Publikováno v:
Bioanalysis. 2(4)
Background: Specificity and sensitivity are essential in assays for immunogenicity assessment of biotherapeutics. Nonspecific interactions from excess therapeutic or anti-therapeutic antibody, soluble ligands (e.g., target receptor), or serum protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7946864c7148bd4606c11d8ce104b1a4
https://pubmed.ncbi.nlm.nih.gov/21083270
https://pubmed.ncbi.nlm.nih.gov/21083270
Autor:
Dan Mytych, Danika Wullner, Dohan Weeraratne, Suzanna M. Tatarewicz, Steven J. Swanson, Michael Moxness, Nancy Murakami, Eugen Koren, Vibha Jawa
Publikováno v:
Clinical chemistry. 51(10)
Monitoring the immune response against human therapeutic monoclonal antibodies is an important component of preclinical and clinical trials to assess drug exposure, efficacy, and safety (1)(2). Detection of antibodies (analyte) directed against thera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75f543b22c8794c32fb9d2185e7b7f45
https://pubmed.ncbi.nlm.nih.gov/16299896
https://pubmed.ncbi.nlm.nih.gov/16299896
Publikováno v:
Clinical Immunology. 123:S155-S156
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa8b23e4aa0eca41bbd8824f3330f70f
https://doi.org/10.1016/j.clim.2007.03.083
https://doi.org/10.1016/j.clim.2007.03.083
Publikováno v:
Clinical Immunology. 119:S130-S131
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3032aba638f24e323781f6d2ff3f159a
https://doi.org/10.1016/j.clim.2006.04.306
https://doi.org/10.1016/j.clim.2006.04.306
Publikováno v:
The Journal of Immunology. 188:174.11-174.11
We have developed and optimized an in vitro functional assay using whole blood derived peripheral blood derived mononuclear cells (PBMC) from non-human primates. The assay was used to quantitate therapeutic specific T cell responses following dosing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b0a930e5de20acbc09b9a141b9ea54d
https://doi.org/10.4049/jimmunol.188.supp.174.11
https://doi.org/10.4049/jimmunol.188.supp.174.11
Autor:
Kinnari Pandya, Vibha Jawa, Steven J. Swanson, Narendra Chirmule, Danika Wullner, Steven Yu, Kevin Salyers, Dohan Weeraratne
Publikováno v:
Clinical Immunology. 135:S107
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::884251d2c9f942cb3ac546dd63e7ccc7
https://doi.org/10.1016/j.clim.2010.03.322
https://doi.org/10.1016/j.clim.2010.03.322