Highlight selection of radiochemistry and radiopharmacy developments by editorial board

Autor: Jun Toyohara, Danielle Vugts, Oliver C. Kiss, Sergio Todde, Xiang-Guo Li, Zhibo Liu, Zhi Yang, Nic Gillings, Emiliano Cazzola, Wiktor Szymanski, Nick van der Meulen, Raymond Reilly, Carlotta Taddei, Ralf Schirrmacher, Zijing Li, Yohannes Jorge Lagebo, Naoual Bentaleb, Marta de Souza Albernaz, Suzanne Lapi, Caterina Ramogida, Archana Mukherjee, Javier Ajenjo, Winnie Deuther-Conrad, Cécile Bourdeau

Publikováno v: EJNMMI Radiopharmacy and Chemistry, Vol 9, Iss 1, Pp 1-20 (2024)

Abstract Background The Editorial Board of EJNMMI Radiopharmacy and Chemistry releases a biannual highlight commentary to update the readership on trends in the field of radiopharmaceutical development. Main body This selection of highlights provides

Externí odkaz: https://doaj.org/article/6980e0880d4947b8b2b09336ab5fc3e4

First exploration of the on-treatment changes in tumor and organ uptake of a radiolabeled anti PD-L1 antibody during chemoradiotherapy in patients with non-small cell lung cancer using whole body PET

Autor: Tanja D de Gruijl, Teodora Radonic, Marc C Huisman, Idris Bahce, Johanna E E Pouw, Sayed M S Hashemi, Jessica E Wijngaarden, Maarten Slebe, Daniela E Oprea-Lager, Gerben J C Zwezerijnen, Danielle Vugts, Ezgi B Ulas, Suresh Senan, C Willemien Menke-van der Houven van Oordt

Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 12, Iss 2 (2024)

Background In patients with locally advanced unresectable non-small cell lung cancer (NSCLC), durvalumab, an anti-programmed cell death ligand-1 (PD-L1) antibody, has shown improved overall survival when used as consolidation therapy following concur

Externí odkaz: https://doaj.org/article/4b3a18abdb6f4a34986c4c57af3d9db7

Highlight selection of radiochemistry and radiopharmacy developments by editorial board (January–June 2020)

Autor: Mohammed Al-Qahtani, Martin Behe, Guy Bormans, Giuseppe Carlucci, Jean Dasilva, Clemens Decristoforo, Philip H. Elsinga, Klaus Kopka, Xiang-Guo Li, Robert Mach, Oskar Middel, Jan Passchier, Marianne Patt, Ivan Penuelas, Ana Rey, Peter J. H. Scott, Sergio Todde, Jun Toyohara, Danielle Vugts

Publikováno v: EJNMMI Radiopharmacy and Chemistry, Vol 6, Iss 1, Pp 1-13 (2021)

Abstract Background The Editorial Board of EJNMMI Radiopharmacy and Chemistry releases a biyearly highlight commentary to describe trends in the field. Results This commentary of highlights has resulted in 19 different topics selected by each member

Externí odkaz: https://doaj.org/article/d10a2e9cd1bf44639f7d44b5f67df959

Pretargeted PET Imaging with a TCO-Conjugated Anti-CD44v6 Chimeric mAb U36 and [89Zr]Zr-DFO-PEG5-Tz

Autor: Dave Lumen, Danielle Vugts, Marion Chomet, Surachet Imlimthan, Mirkka Sarparanta, Ricardo Vos, Maxime Schreurs, Mariska Verlaan, Pauline A. Lang, Eero Hippeläinen, Wissam Beaino, Albert D. Windhorst, Anu J. Airaksinen

Publikováno v: Lumen, D, Vugts, D, Chomet, M, Imlimthan, S, Sarparanta, M, Vos, R, Schreurs, M, Verlaan, M, Lang, P A, Hippeläinen, E, Beaino, W, Windhorst, A D & Airaksinen, A J 2022, ' Pretargeted PET Imaging with a TCO-Conjugated Anti-CD44v6 Chimeric mAb U36 and [89Zr]Zr-DFO-PEG5-Tz ', Bioconjugate chemistry, vol. 33, no. 5, pp. 956-968 . https://doi.org/10.1021/acs.bioconjchem.2c00164
Bioconjugate chemistry, 33(5), 956-968. American Chemical Society

The recent advances in the production of engineered antibodies have facilitated the development and application of tailored, target-specific antibodies. Positron emission tomography (PET) of these antibody-based drug candidates can help to better und

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9303fabee94f0e86e8d38f0c62156b58
https://research.vumc.nl/en/publications/fb160ada-3f47-43a5-8d49-1816af8ce10b

The Development of Positron Emission Tomography Tracers for In Vivo Targeting the Kinase Domain of the Epidermal Growth Factor Receptor

Autor: Antonia Högnäsbacka, Alex Poot, Danielle Vugts, Guus van Dongen, Albert Windhorst

Publikováno v: Högnäsbacka, A, Poot, A J, Vugts, D J, van Dongen, G A M S & Windhorst, A D 2022, ' The Development of Positron Emission Tomography Tracers for In Vivo Targeting the Kinase Domain of the Epidermal Growth Factor Receptor ', Pharmaceuticals, vol. 15, no. 4, 450 . https://doi.org/10.3390/ph15040450

Multiple small molecule PET tracers have been developed for the imaging of the epidermal growth factor receptor (EGFR). These tracers target the tyrosine kinase (TK) domain of the receptor and have been used for both quantifying EGFR expression and t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dd06ad7b19097c1136672414e61fec6
https://research.vumc.nl/en/publications/1a80a8a7-40e3-4b51-a96f-545f664f13bc