Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Danielle Senyschyn"'
Autor:
Tim Quach, Luojuan Hu, Sifei Han, Shea F. Lim, Danielle Senyschyn, Preeti Yadav, Natalie L. Trevaskis, Jamie S. Simpson, Christopher J. H. Porter
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/028048587b0e4741b75102697e74ef15
Autor:
Tim Quach, Luojuan Hu, Sifei Han, Shea F. Lim, Danielle Senyschyn, Preeti Yadav, Natalie L. Trevaskis, Jamie S. Simpson, Christopher J. H. Porter
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Buprenorphine (BUP) is a potent opioid analgesic that is widely used for severe pain management and opioid replacement therapy. The oral bioavailability of BUP, however, is significantly limited by first-pass metabolism. Previous studies have shown t
Externí odkaz:
https://doaj.org/article/075b84dedb714267a4a31fc5ae8108b9
Autor:
Alina D. Lam, Ian K. Styles, Danielle Senyschyn, Enyuan Cao, Abel Anshabo, Mohammad Abdallah, Reyaj Mikrani, Cameron J. Nowell, Christopher J. H. Porter, Orlagh M. Feeney, Natalie L. Trevaskis
Publikováno v:
Molecular Pharmaceutics. 20:2053-2066
Autor:
Reyaj Mikrani, Ian K. Styles, Thu A. Hoang, Mohammad Abdallah, Danielle Senyschyn, Christopher J.H. Porter, Enyuan Cao, Natalie L. Trevaskis
Publikováno v:
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 180
Dietary lipids, highly lipophilic drugs, antigens and immune cells are transported from the intestine to the mesenteric lymph nodes (MLNs) via mesenteric lymphatic vessels. Recently our lab reported that the mesenteric lymphatic vessels become highly
Autor:
Preeti Verma, Peter R. Shea, Rajbharan Yadav, Danielle Senyschyn, Natalie L. Trevaskis, Sunil Kumar Prajapati
Publikováno v:
Molecular Pharmaceutics. 13:3688-3699
Vesicular and colloidal delivery systems can be designed to control drug release spatially and temporally to improve drug efficacy and side effect profiles. Niosomes (vesicles prepared from nonionic surfactants in aqueous media) are gaining interest
Autor:
Christopher Yap, Durgesh Tiwari, Joseph A. Nicolazzo, Kwok Ho Christopher Choy, Jennifer L. Short, Danielle Senyschyn, Stephanie A. Newman, Yijun Pan, William A. Banks
Publikováno v:
Brain, behavior, and immunity. 70
Epidemiological evidence suggests that people with bipolar disorder prescribed lithium exhibit a lower risk of Alzheimer’s disease (AD) relative to those prescribed other mood-stabilizing medicines. Lithium chloride (LiCl) reduces brain β-amyloid
Autor:
Luojuan Hu, Tim Quach, Sifei Han, Shea F. Lim, Preeti Yadav, Danielle Senyschyn, Natalie L. Trevaskis, Jamie S. Simpson, Christopher J. H. Porter
Publikováno v:
Angewandte Chemie International Edition. 55
Autor:
Danielle Senyschyn, Christopher J.H. Porter, Natalie L. Trevaskis, Tim Quach, Jamie S. Simpson, Shea Fern Lim, Luojuan Hu, Preeti Yadav, Sifei Han
Publikováno v:
Angewandte Chemie (International ed. in English). 55(44)
First-pass hepatic metabolism can significantly limit oral drug bioavailability. Drug transport from the intestine through the lymphatic system, rather than the portal vein, circumvents first-pass metabolism. However, the majority of drugs do not hav
Autor:
Aradhana Upadhyay, Jalal A. Jazayeri, Graeme J Carroll, Ran Gu, Danielle Senyschyn, Leilani Llanes Santos
Publikováno v:
Clinical and Experimental Immunology. 169:71-78
Summary This study is investigating the role of leukaemia inhibitory factor (LIF) in the development of inflammation and joint damage in the mouse K/B×N serum transfer arthritis model. LIF knock-out (LIF−/−) mice were generated by mating heteroz
Autor:
Terence P. Speed, Simon J. Foote, Enmoore Lin, Melanie Bahlo, Tony Pappenfuss, Rachel B. Tan, Danielle Senyschyn
Publikováno v:
Infection and Immunity. 74:5814-5819
Animals congenic for the char2 host response locus to the murine malarial parasite Plasmodium chabaudi have been bred, and they demonstrated a phenotypic difference from the parental lines. These congenic lines have been crossed back to the parental