Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Danielle Santana-Coelho"'
Autor:
Danielle Santana-Coelho
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 40, Iss , Pp 100839- (2024)
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by deficits in communication, sociability, and repetitive/stereotyped behavior. The etiology of autism is diverse, with genetic susceptibility playing an important role alo
Externí odkaz:
https://doaj.org/article/6cd6c29571ec4355970173859dfba7ed
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 11, Pp 9306-9315 (2023)
The complement system is part of the innate immune system and has been shown to be altered in autism spectrum disorder (ASD). Fragile-X syndrome (FXS) is the main genetic cause of ASD and studies suggest a dysregulation in the immune system in patien
Externí odkaz:
https://doaj.org/article/802551c21b9c4ef9935e7090b09bf23c
Autor:
Danielle Santana‐Coelho, Samantha L. Hodges, Saul I. Quintero, Paige D. Womble, D. Greg Sullens, David A. Narvaiz, Rebecca Herrera, Melanie J. Sekeres, Joaquin N. Lugo
Publikováno v:
Brain and Behavior, Vol 13, Iss 8, Pp n/a-n/a (2023)
Abstract Objectives Fragile X syndrome is the main monogenetic cause of intellectual disability and autism. Alterations in the immune system are commonly found in these developmental disorders. We and others have demonstrated that Fmr1 mutant mice pr
Externí odkaz:
https://doaj.org/article/a7050befed384236a611bb5243684464
Autor:
Alexandre G. Maganin, Guilherme R. Souza, Miriam D. Fonseca, Alexandre H. Lopes, Rafaela M. Guimarães, André Dagostin, Nerry T. Cecilio, Atlante S. Mendes, William A. Gonçalves, Conceição E.A. Silva, Francisco Isaac Fernandes Gomes, Lucas M. Mauriz Marques, Rangel L. Silva, Letícia M. Arruda, Denis A. Santana, Henrique Lemos, Lei Huang, Marcela Davoli-Ferreira, Danielle Santana-Coelho, Morena B. Sant’Anna, Ricardo Kusuda, Jhimmy Talbot, Gabriela Pacholczyk, Gabriela A. Buqui, Norberto P. Lopes, Jose C. Alves-Filho, Ricardo M. Leão, Jason C. O’Connor, Fernando Q. Cunha, Andrew Mellor, Thiago M. Cunha
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 23 (2022)
Neuropathic pain is one of the most important clinical consequences of injury to the somatosensory system. Nevertheless, the critical pathophysiological mechanisms involved in neuropathic pain development are poorly understood. In this study, we foun
Externí odkaz:
https://doaj.org/article/c98ec044e03d4d9d88b85df1bc7f3f13
Autor:
Danielle Santana-Coelho, Donna Layne-Colon, Roslyn Valdespino, Corinna C. Ross, Suzette D. Tardif, Jason C. O'Connor
Publikováno v:
Frontiers in Psychiatry, Vol 12 (2021)
Understanding the mechanism(s) by which maternal immune activation (MIA) during gestation may disrupt neurodevelopment and increase the susceptibility for disorders such as autism spectrum disorder (ASD) or schizophrenia is a critical step in the dev
Externí odkaz:
https://doaj.org/article/f587fc139c254379a88eb1c44bda4041
Publikováno v:
Cells, Vol 10, Iss 6, p 1548 (2021)
Diseases of the central nervous system (CNS) remain a significant health, social and economic problem around the globe. The development of therapeutic strategies for CNS conditions has suffered due to a poor understanding of the underlying pathologie
Externí odkaz:
https://doaj.org/article/736609b939384dfca6053e946d465997
Publikováno v:
Neuroreport. 33(11)
Seizures induce brain region-dependent enhancements in microglia/macrophage activation. Neuronal subset-specific phosphatase and tensin homolog (PTEN) knockout (KO) mice display hyperactive mammalian target of rapamycin (mTOR) signaling in the hippoc
Autor:
Danielle Santana‐Coelho, Paige D. Womble, Katherine J. Blandin, Jacob B. Pilcher, Grace M. O'Neill, Leighton A. Douglas, Srikhar V. Chilukuri, Doan L. K. Tran, Taylor A. Wiley, Joaquin N. Lugo
Publikováno v:
Developmental psychobiologyREFERENCES. 64(8)
Isolation-induced ultrasonic vocalizations (USVs) are important to elicit parental retrieval. This behavior is critical for the animal's survival and can be altered in models of developmental disorders. The potentiation of vocalizations in response t
Autor:
Alexandre G. Maganin, Guilherme R. Souza, Miriam D. Fonseca, Alexandre H. Lopes, Rafaela M. Guimarães, André Dagostin, Nerry T. Cecilio, Atlante S. Mendes, William A. Gonçalves, Conceição E.A. Silva, Francisco Isaac Fernandes Gomes, Lucas M. Mauriz Marques, Rangel L. Silva, Letícia M. Arruda, Denis A. Santana, Henrique Lemos, Lei Huang, Marcela Davoli-Ferreira, Danielle Santana-Coelho, Morena B. Sant’Anna, Ricardo Kusuda, Jhimmy Talbot, Gabriela Pacholczyk, Gabriela A. Buqui, Norberto P. Lopes, Jose C. Alves-Filho, Ricardo M. Leão, Jason C. O’Connor, Fernando Q. Cunha, Andrew Mellor, Thiago M. Cunha
Publikováno v:
The Journal of clinical investigation. 132(23)
Neuropathic pain is one of the most important clinical consequences of injury to the somatosensory system. Nevertheless, the critical pathophysiological mechanisms involved in neuropathic pain development are poorly understood. In this study, we foun
Autor:
Jason C. O’Connor, Corinna Ross, Danielle Santana-Coelho, Suzette D. Tardif, Donna Layne-Colon, Roslyn Valdespino
Publikováno v:
Frontiers in Psychiatry, Vol 12 (2021)
Frontiers in Psychiatry
Frontiers in Psychiatry
Understanding the mechanism(s) by which maternal immune activation (MIA) during gestation may disrupt neurodevelopment and increase the susceptibility for disorders such as autism spectrum disorder (ASD) or schizophrenia is a critical step in the dev