Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Danielle S. Potter"'
Autor:
Danielle S. Potter, Ruochen Du, Stephan R. Bohl, Kin-Hoe Chow, Keith L. Ligon, Raphael Bueno, Anthony Letai
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Malignant pleural mesothelioma (MPM) has relatively ineffective first/second-line therapy for advanced disease and only 18% five-year survival for early disease. Drug-induced mitochondrial priming measured by dynamic BH3 profiling identifies
Externí odkaz:
https://doaj.org/article/1d17f8fe98d348939d13271ba1919296
Publikováno v:
Cell Death and Disease, Vol 12, Iss 8, Pp 1-12 (2021)
Abstract Conventional chemotherapy is still of great utility in oncology and rationally constructing combinations with it remains a top priority. Drug-induced mitochondrial apoptotic priming, measured by dynamic BH3 profiling (DBP), has been shown in
Externí odkaz:
https://doaj.org/article/e8949a4d649644b19e9e69477ec422a2
Autor:
Danielle S. Potter, Paul Kelly, Olive Denneny, Veronique Juvin, Len R. Stephens, Caroline Dive, Christopher J. Morrow
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 16, Iss 2, Pp 147-157 (2014)
Evasion of apoptosis is a hallmark of cancer, and reversing this process by inhibition of survival signaling pathways is a potential therapeutic strategy. Phosphoinositide 3-kinase (PI3K) signaling can promote cell survival and is upregulated in soli
Externí odkaz:
https://doaj.org/article/ae8a624245924a3fb3b4e566ba850545
Autor:
Caroline Dive, Christopher J. Morrow, Fiona Blackhall, Cassandra L. Hodgkinson, Alice Lallo, Stewart Brown, Melanie Galvin, Danielle S. Potter
Supplementary Figure 7. In vivo tolerance study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f0fb09359b02ca5d4b9964ebd614cc3
https://doi.org/10.1158/1535-7163.22504056.v1
https://doi.org/10.1158/1535-7163.22504056.v1
Autor:
Caroline Dive, Christopher J. Morrow, Fiona Blackhall, Cassandra L. Hodgkinson, Alice Lallo, Stewart Brown, Melanie Galvin, Danielle S. Potter
Supplementary Figure 3. H524 cytotoxicity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59e21e1b90985aa552c16dad330473d9
https://doi.org/10.1158/1535-7163.22504068.v1
https://doi.org/10.1158/1535-7163.22504068.v1
Autor:
Caroline Dive, Christopher J. Morrow, Fiona Blackhall, Cassandra L. Hodgkinson, Alice Lallo, Stewart Brown, Melanie Galvin, Danielle S. Potter
Most small cell lung cancer (SCLC) patients are initially responsive to cytotoxic chemotherapy, but almost all undergo fatal relapse with progressive disease, highlighting an urgent need for improved therapies and better patient outcomes in this dise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::952f3065b642538e7a8ab422fa011d5d
https://doi.org/10.1158/1535-7163.c.6537609
https://doi.org/10.1158/1535-7163.c.6537609
Autor:
Caroline Dive, Christopher J. Morrow, Fiona Blackhall, Cassandra L. Hodgkinson, Alice Lallo, Stewart Brown, Melanie Galvin, Danielle S. Potter
Supplementary Figure 6. Statistics for knockdown experiments
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::150ad97bcdc1e96c4a8ff05e3883eba3
https://doi.org/10.1158/1535-7163.22504059.v1
https://doi.org/10.1158/1535-7163.22504059.v1
Autor:
Caroline Dive, Christopher J. Morrow, Fiona Blackhall, Cassandra L. Hodgkinson, Alice Lallo, Stewart Brown, Melanie Galvin, Danielle S. Potter
Supplementary Figure 5. Bcl2 family expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a19c597c2888127ba2fc0c5ae9b7cf98
https://doi.org/10.1158/1535-7163.22504062.v1
https://doi.org/10.1158/1535-7163.22504062.v1
Autor:
Caroline Dive, Christopher J. Morrow, Fiona Blackhall, Cassandra L. Hodgkinson, Alice Lallo, Stewart Brown, Melanie Galvin, Danielle S. Potter
Supplementary Figure 2. Cyotoxicity assays
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de254144bdb0c887d306e8087da60f6c
https://doi.org/10.1158/1535-7163.22504071.v1
https://doi.org/10.1158/1535-7163.22504071.v1
Autor:
Caroline Dive, Christopher J. Morrow, Fiona Blackhall, Cassandra L. Hodgkinson, Alice Lallo, Stewart Brown, Melanie Galvin, Danielle S. Potter
Supplementary Figure 1. BMX expression in SCLC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1316d03dc78ff48a2af6fd6f60eeb927
https://doi.org/10.1158/1535-7163.22504074.v1
https://doi.org/10.1158/1535-7163.22504074.v1