Zobrazeno 1 - 10
of 120
pro vyhledávání: '"Danielle S W Benoit"'
Publikováno v:
PLoS ONE, Vol 13, Iss 5, p e0197031 (2018)
Blood flow changes during bone graft healing have the potential to provide important information about graft success, as the nutrients, oxygen, circulating cells and growth factors essential for integration are delivered by blood. However, longitudin
Externí odkaz:
https://doaj.org/article/3ec405fbe2c042008a0ca7a4ad5a5838
Autor:
Songfeng Han, Michael D Hoffman, Ashley R Proctor, Joseph B Vella, Emmanuel A Mannoh, Nathaniel E Barber, Hyun Jin Kim, Ki Won Jung, Danielle S W Benoit, Regine Choe
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0143891 (2015)
Vascular infiltration and associated alterations in microvascular blood flow are critical for complete bone graft healing. Therefore, real-time, longitudinal measurement of blood flow has the potential to successfully predict graft healing outcomes.
Externí odkaz:
https://doaj.org/article/462283502dfe4746b1899e24d400fb03
Autor:
Yuanhui Song, Hitoshi Uchida, Azmeer Sharipol, Lindsay Piraino, Jared A. Mereness, Matthew H. Ingalls, Jonathan Rebhahn, Shawn D. Newlands, Lisa A. DeLouise, Catherine E. Ovitt, Danielle S. W. Benoit
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
Song, Uchida, and Sharipol et al. develop functional tissue mimetics for mouse and human salivary glands by combining engineered extracellular matrices with microbubble array technology. The resulting tissue mimetics emulate phenotype and function of
Externí odkaz:
https://doaj.org/article/9b358e51fdcd44d791f1765e988cf0e6
Autor:
Aurea Simon-Soro, Dongyeop Kim, Yong Li, Yuan Liu, Tatsuro Ito, Kenneth R. Sims, Danielle S. W. Benoit, Kyle Bittinger, Hyun Koo
Publikováno v:
npj Biofilms and Microbiomes, Vol 7, Iss 1, Pp 1-9 (2021)
Abstract Drug repurposing is a feasible strategy for the development of novel therapeutic applications. However, its potential use for oral treatments and impact on host microbiota remain underexplored. Here, we assessed the influences of topical ora
Externí odkaz:
https://doaj.org/article/b667744803a34606af4ae636325d7c88
Publikováno v:
Frontiers in Dental Medicine, Vol 3 (2022)
Periodontitis is a widespread inflammatory disease that leads to loss of the tooth supporting periodontal tissues. The few therapies available to regenerate periodontal tissues have high costs and inherent limitations, inspiring the development of ne
Externí odkaz:
https://doaj.org/article/d2f3363fb9044ada839cdded93d2d19a
Publikováno v:
Cells, Vol 11, Iss 12, p 1962 (2022)
The development of therapies to prevent or treat salivary gland dysfunction has been limited by a lack of functional in vitro models. Specifically, critical markers of salivary gland secretory phenotype downregulate rapidly ex vivo. Here, we utilize
Externí odkaz:
https://doaj.org/article/cd78e068aff0403fbc6e01b19162a1cc
Autor:
Margaret A. T. Freeberg, Youssef M. Farhat, Anas Easa, Jacob G. Kallenbach, Dominic W. Malcolm, Mark R. Buckley, Danielle S. W. Benoit, Hani A. Awad
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Abstract Injuries to flexor tendons can be complicated by fibrotic adhesions, which severely impair the function of the hand. Adhesions have been associated with TGF-β1, which causes upregulation of PAI-1, a master suppressor of protease activity, i
Externí odkaz:
https://doaj.org/article/e5cdfd5cb21341d4a50f60bcc3be2d10
Publikováno v:
Cells, Vol 10, Iss 7, p 1723 (2021)
Salivary gland regeneration is important for developing treatments for radiation-induced xerostomia, Sjögren’s syndrome, and other conditions that cause dry mouth. Culture conditions adopted from tissue engineering strategies have been used to rec
Externí odkaz:
https://doaj.org/article/240f2d6b4edf4f40840575c00e6f8f2f
Autor:
Tatsuro Ito, Kenneth R. Sims, Yuan Liu, Zhenting Xiang, Rodrigo A. Arthur, Anderson T. Hara, Hyun Koo, Danielle S. W. Benoit, Marlise I. Klein
Publikováno v:
Molecular Oral Microbiology. 37:218-228
Streptococcus mutans and Candida albicans are frequently detected together in the plaque from patients with early childhood caries (ECC) and synergistically interact to form a cariogenic cross-kingdom biofilm. However, this biofilm is difficult to co
Autor:
David Fraser, Tram Nguyen, Alexander Kotelsky, Whasil Lee, Mark Buckley, Danielle S. W. Benoit
Publikováno v:
ACS Biomaterials Science & Engineering. 8:3568-3575
Cell and tissue alignment is a defining feature of periodontal tissues. Therefore, the development of scaffolds that can guide alignment of periodontal ligament cells (PDLCs) relative to tooth root (dentin) surfaces is highly relevant for periodontal