Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Danielle Pinkiert"'
Autor:
Melissa L. Abel, Nobuyuki Takahashi, Cody Peer, Christophe E. Redon, Samantha Nichols, Rasa Vilimas, Min-Jung Lee, Sunmin Lee, Meenakshi Shelat, Robbie Kattappuram, Linda Sciuto, Danielle Pinkiert, Chante Graham, Donna Butcher, Baktiar Karim, Ajit Kumar Sharma, Justin Malin, Rajesh Kumar, Christopher W. Schultz, Shubhank Goyal, Jaydira del Rivero, Manan Krishnamurthy, Deep Upadhyay, Brett Schroeder, Tristan Sissung, Manoj Tyagi, Jung Kim, Yves Pommier, Mirit Aladjem, Mark Raffeld, William Douglas Figg, Jane Trepel, Liqiang Xi, Parth Desai, Anish Thomas
Publikováno v:
Clinical Cancer Research. :OF1-OF9
Purpose: Despite promising preclinical studies, toxicities have precluded combinations of chemotherapy and DNA damage response (DDR) inhibitors. We hypothesized that tumor-targeted chemotherapy delivery might enable clinical translation of such combi
Autor:
Anish Thomas, Parth Desai, Liqiang Xi, Jane Trepel, William Douglas Figg, Mark Raffeld, Mirit Aladjem, Yves Pommier, Jung Kim, Manoj Tyagi, Tristan Sissung, Brett Schroeder, Deep Upadhyay, Manan Krishnamurthy, Jaydira del Rivero, Shubhank Goyal, Christopher W. Schultz, Rajesh Kumar, Justin Malin, Ajit Kumar Sharma, Baktiar Karim, Donna Butcher, Chante Graham, Danielle Pinkiert, Linda Sciuto, Robbie Kattappuram, Meenakshi Shelat, Sunmin Lee, Min-Jung Lee, Rasa Vilimas, Samantha Nichols, Christophe E. Redon, Cody Peer, Nobuyuki Takahashi, Melissa L. Abel
Study Representativeness
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1134469c3d0836c8a00a656b51d038b1
https://doi.org/10.1158/1078-0432.23183836
https://doi.org/10.1158/1078-0432.23183836
Autor:
Anish Thomas, Parth Desai, Liqiang Xi, Jane Trepel, William Douglas Figg, Mark Raffeld, Mirit Aladjem, Yves Pommier, Jung Kim, Manoj Tyagi, Tristan Sissung, Brett Schroeder, Deep Upadhyay, Manan Krishnamurthy, Jaydira del Rivero, Shubhank Goyal, Christopher W. Schultz, Rajesh Kumar, Justin Malin, Ajit Kumar Sharma, Baktiar Karim, Donna Butcher, Chante Graham, Danielle Pinkiert, Linda Sciuto, Robbie Kattappuram, Meenakshi Shelat, Sunmin Lee, Min-Jung Lee, Rasa Vilimas, Samantha Nichols, Christophe E. Redon, Cody Peer, Nobuyuki Takahashi, Melissa L. Abel
Pharmacokinetic assessment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b06619753b143d9112a4bb0c3cb9b8e1
https://doi.org/10.1158/1078-0432.23183851.v1
https://doi.org/10.1158/1078-0432.23183851.v1
Autor:
Anish Thomas, Parth Desai, Liqiang Xi, Jane Trepel, William Douglas Figg, Mark Raffeld, Mirit Aladjem, Yves Pommier, Jung Kim, Manoj Tyagi, Tristan Sissung, Brett Schroeder, Deep Upadhyay, Manan Krishnamurthy, Jaydira del Rivero, Shubhank Goyal, Christopher W. Schultz, Rajesh Kumar, Justin Malin, Ajit Kumar Sharma, Baktiar Karim, Donna Butcher, Chante Graham, Danielle Pinkiert, Linda Sciuto, Robbie Kattappuram, Meenakshi Shelat, Sunmin Lee, Min-Jung Lee, Rasa Vilimas, Samantha Nichols, Christophe E. Redon, Cody Peer, Nobuyuki Takahashi, Melissa L. Abel
Comparison of treatment-related adverse events with the combination of berzosertib and topotecan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e72670bce263b55224e479efc572baf
https://doi.org/10.1158/1078-0432.23183842
https://doi.org/10.1158/1078-0432.23183842
Autor:
Anish Thomas, Parth Desai, Liqiang Xi, Jane Trepel, William Douglas Figg, Mark Raffeld, Mirit Aladjem, Yves Pommier, Jung Kim, Manoj Tyagi, Tristan Sissung, Brett Schroeder, Deep Upadhyay, Manan Krishnamurthy, Jaydira del Rivero, Shubhank Goyal, Christopher W. Schultz, Rajesh Kumar, Justin Malin, Ajit Kumar Sharma, Baktiar Karim, Donna Butcher, Chante Graham, Danielle Pinkiert, Linda Sciuto, Robbie Kattappuram, Meenakshi Shelat, Sunmin Lee, Min-Jung Lee, Rasa Vilimas, Samantha Nichols, Christophe E. Redon, Cody Peer, Nobuyuki Takahashi, Melissa L. Abel
Whole exome sequencing results
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10e0703d0491a2e65773002543835b16
https://doi.org/10.1158/1078-0432.23183839.v1
https://doi.org/10.1158/1078-0432.23183839.v1
Autor:
Anish Thomas, Parth Desai, Liqiang Xi, Jane Trepel, William Douglas Figg, Mark Raffeld, Mirit Aladjem, Yves Pommier, Jung Kim, Manoj Tyagi, Tristan Sissung, Brett Schroeder, Deep Upadhyay, Manan Krishnamurthy, Jaydira del Rivero, Shubhank Goyal, Christopher W. Schultz, Rajesh Kumar, Justin Malin, Ajit Kumar Sharma, Baktiar Karim, Donna Butcher, Chante Graham, Danielle Pinkiert, Linda Sciuto, Robbie Kattappuram, Meenakshi Shelat, Sunmin Lee, Min-Jung Lee, Rasa Vilimas, Samantha Nichols, Christophe E. Redon, Cody Peer, Nobuyuki Takahashi, Melissa L. Abel
Berzosertib pharmacodynamic assessment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acba7feecd4e5f38e76f50e2414abf96
https://doi.org/10.1158/1078-0432.23183854.v1
https://doi.org/10.1158/1078-0432.23183854.v1
Autor:
Anish Thomas, Parth Desai, Liqiang Xi, Jane Trepel, William Douglas Figg, Mark Raffeld, Mirit Aladjem, Yves Pommier, Jung Kim, Manoj Tyagi, Tristan Sissung, Brett Schroeder, Deep Upadhyay, Manan Krishnamurthy, Jaydira del Rivero, Shubhank Goyal, Christopher W. Schultz, Rajesh Kumar, Justin Malin, Ajit Kumar Sharma, Baktiar Karim, Donna Butcher, Chante Graham, Danielle Pinkiert, Linda Sciuto, Robbie Kattappuram, Meenakshi Shelat, Sunmin Lee, Min-Jung Lee, Rasa Vilimas, Samantha Nichols, Christophe E. Redon, Cody Peer, Nobuyuki Takahashi, Melissa L. Abel
Purpose:Despite promising preclinical studies, toxicities have precluded combinations of chemotherapy and DNA damage response (DDR) inhibitors. We hypothesized that tumor-targeted chemotherapy delivery might enable clinical translation of such combin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc7577de8e937edbaabfad8bf2398a84
https://doi.org/10.1158/1078-0432.c.6664579.v1
https://doi.org/10.1158/1078-0432.c.6664579.v1
Autor:
Anish Thomas, Parth Desai, Liqiang Xi, Jane Trepel, William Douglas Figg, Mark Raffeld, Mirit Aladjem, Yves Pommier, Jung Kim, Manoj Tyagi, Tristan Sissung, Brett Schroeder, Deep Upadhyay, Manan Krishnamurthy, Jaydira del Rivero, Shubhank Goyal, Christopher W. Schultz, Rajesh Kumar, Justin Malin, Ajit Kumar Sharma, Baktiar Karim, Donna Butcher, Chante Graham, Danielle Pinkiert, Linda Sciuto, Robbie Kattappuram, Meenakshi Shelat, Sunmin Lee, Min-Jung Lee, Rasa Vilimas, Samantha Nichols, Christophe E. Redon, Cody Peer, Nobuyuki Takahashi, Melissa L. Abel
PK results vs toxicity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44e48fffd5d79da10c322c61d7b8a4ab
https://doi.org/10.1158/1078-0432.23183845.v1
https://doi.org/10.1158/1078-0432.23183845.v1
Autor:
Melissa L. Abel, Nobukyuki Takahashi, Parth Desai, Cody Peer, Christophe Redon, Samantha Nichols, Rasa Vilimas, Min-Jung Lee, Sunmin Lee, Linda Sciuto, Danielle Pinkiert, Meenakshi Shelat, Chante Graham, Seth Steinberg, William D. Figg, Mirit Aladjem, Jane Trepel, Yves Pommier, Anish Thomas
Publikováno v:
Cancer Research. 83:CT268-CT268
Despite provocative preclinical results, dose-limiting toxicities have precluded rational combinations of cytotoxic chemotherapies that increase DNA damage with DNA damage response (DDR) inhibitors. We hypothesized that tumor-targeted delivery of cyt