Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Danielle Paixão-Cavalcante"'
Autor:
Danielle Paixão-Cavalcante, Alexandre K Kuniyoshi, Fernanda C V Portaro, Wilmar Dias da Silva, Denise V Tambourgi
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 9, Iss 2, p e0003419 (2015)
BACKGROUND:An alarming number of fatal accidents involving snakes are annually reported in Africa and most of the victims suffer from permanent local tissue damage and chronic disabilities. Envenomation by snakes belonging to the genus Bitis, Viperid
Externí odkaz:
https://doaj.org/article/48e5a801e59743a8ba3826071056e2fc
Publikováno v:
Journal of Nanoparticle Research
Nanoparticles may be used in vaccinology as an antigen delivery and/or an immunostimulant to enhance immunity. Porous silica has been identified as an effective adjuvant for more than a decade, and we have therefore investigated the take up rate by a
Autor:
Denise V. Tambourgi, Paulo R. A. F. Garcia, Gabriela D. Tanaka, Marcos Tadeu D’Azeredo Orlando, Joel José Megale Gabrili, Francisco Mariano Neto, Danielle Paixão-Cavalcante, Juliana Mussalem, Denise Cristina André Oliveira, Viviane Fongaro Botosso, Márcia Carvalho de Abreu Fantini, Osvaldo A. Sant'Anna, Karina Scaramuzzi, Cristiano L. P. Oliveira
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Due to its physicochemical properties, nanostructured mesoporous SBA-15 silica shows great potential as a vaccine adjuvant. This study evaluated the capacity of SBA-15 to encapsulate/adsorb the recombinant purified HBsAg from the Hepatitis B virus an
Autor:
Claire L. Harris, Santiago Rodríguez de Córdoba, B. Paul Morgan, Eva Torreira, Oscar Llorca, Danielle Paixão-Cavalcante, Margaret A. Lindorfer, Ronald P. Taylor
Publikováno v:
The Journal of Immunology. 192:4844-4851
Dysregulation of the complement alternative pathway can cause disease in various organs that may be life-threatening. Severe alternative pathway dysregulation can be triggered by autoantibodies to the C3 convertase, termed nephritic factors, which ca
Autor:
Timothy H.J. Goodship, Lennart Truedsson, Patricia C. Giclas, Danielle Paixão-Cavalcante, B. Paul Morgan, Claire L. Harris, Margarita López-Trascasa, Santiago Rodríguez de Córdoba, Lillemor Skattum
Publikováno v:
Kidney International
C3 nephritic factors are autoantibodies that prolong the half-life or prevent regulation of the alternative pathway C3 convertase, resulting in uncontrolled complement activation. They are strongly associated with renal disease but their role in path
Autor:
Frances McCormick, David J. Kavanagh, Iain Moore, C Hayes, Christoph Q. Schmidt, Eva-Maria Hunze, Kevin J. Marchbank, Tibor Toth, Paul N. Barlow, Scott J. Staniforth, David Warland, Mark Denton, Kris Houlberg, Isabel Y. Pappworth, Lisa Strain, Timothy H.J. Goodship, Claire L. Harris, Danielle Paixão Cavalcante, Andrew P. Herbert
Publikováno v:
Molecular Immunology. 52:200-206
Factor H autoantibodies are found in ~10% of aHUS patients. Most are associated with complete deficiency of factor H related proteins 1/3 and bind to the C terminal recognition domain. MPGN, like aHUS, is characterised by complement activation. In th
Autor:
H. Terence Cook, Danielle Paixão-Cavalcante, Marina Botto, Steven Hanson, Matthew C. Pickering
Publikováno v:
Molecular Immunology
Dense deposit disease (DDD) is strongly associated with the uncontrolled activation of the complement alternative pathway. Factor H (CFH)-deficient (Cfh(-/-)) mice spontaneously develop C3 deposition along the glomerular basement membrane (GBM) with
Publikováno v:
Clinical and Experimental Immunology. 155:339-347
Summary Haemolytic uraemic syndrome (HUS) is characterized by microangiopathic haemolytic anaemia, thrombocytopenia and renal failure because of thrombotic microangiopathy (TMA). It may be caused by infection with Shiga toxin-producing enteropathic b
Autor:
Dewton Moraes-Vasconcelos, Mariane Tami Amano, Alberto José da Silva Duarte, Anete Sevciovic Grumach, M. P. C. Florido, Danielle Paixão-Cavalcante, E. S. Reis, D. A. Falcão, Jose Antonio Tavares de Albuquerque, Maria Isabel Delcolli, Lourdes Isaac
Publikováno v:
Scandinavian Journal of Immunology. 68:445-455
We identified a 4-year-old Brazilian boy from a family of Japanese descent and history of consanguinity, who suffered from severe recurrent pneumonia. He carries factor H (FH) deficiency associated with reduced levels of component C9 and low serum le
Autor:
Carmen W. van den Berg, Cinthya Kimori Okamoto, Rute M. Gonçalves-de-Andrade, Matheus F. Fernandes-Pedrosa, Danielle Paixão-Cavalcante, Denise V. Tambourgi
Publikováno v:
Journal of Investigative Dermatology. 127(6):1410-1418
Envenomation by spiders belonging to the Loxosceles genus (brown spider) often results in local dermonecrotic lesions. We have previously shown that Loxosceles sphingomyelinase D (SMase D), the venom component responsible for all the pathological eff